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Author Details

Kolja Eppert
McGill University
1996
24
21
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
33147339CD200 expression marks leukemia stem cells in human AML.Blood Adv2020
31196146Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation.J Exp Clin Cancer Res2019
31540977Mechanisms and Antitumor Activity of a Binary EGFR/DNA-Targeting Strategy Overcomes Resistance of Glioblastoma Stem Cells to Temozolomide.Clin Cancer Res2019
31253791Mutant H3 histones drive human pre-leukemic hematopoietic stem cell expansion and promote leukemic aggressiveness.Nat Commun2019
29921955Leukemic stem cell signatures identify novel therapeutics targeting acute myeloid leukemia.Blood Cancer J2018
28481221Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells.J Clin Invest2017
26832662miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.Cancer Cell2016
27473565Complement cascade gene expression defines novel prognostic subgroups of acute myeloid leukemia.Exp Hematol2016
27437771Barriers to horizontal cell transformation by extracellular vesicles containing oncogenic H-ras.Oncotarget2016
26834243GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo.Blood2016
27070706miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.Cancer Cell2016
24388174Reduced lymphoid lineage priming promotes human hematopoietic stem cell expansion.Cell Stem Cell2014
24776803The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress.Nature2014
23202731Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors.J Clin Invest2013
22160482A small molecule screening strategy with validation on human leukemia stem cells uncovers the therapeutic efficacy of kinetin riboside.Blood2012
22237106The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.Nature2012
21873988Stem cell gene expression programs influence clinical outcome in human leukemia.Nat Med2011
20404133Comparison of human cord blood engraftment between immunocompromised mouse strains.Blood2010
20543838Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development.Nat Immunol2010
20619763A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal.Cell Stem Cell2010
15467717von Willebrand factor expression in osteosarcoma metastasis.Mod Pathol2005
15609301Altered expression and deletion of RMO1 in osteosarcoma.Int J Cancer2005
8893761SAS is amplified predominantly in surface osteosarcoma.J Orthop Res1996
8752209MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma.Cell1996
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Collaborators

John E Dick
Princess Margaret Cancer Centre, University Health Network
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Faiyaz Notta
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Co-authored papers 4
Meaghan Boileau
Ottawa Hospital Research Institute
Co-authored papers 4
Irene L Andrulis
University of Toronto
Co-authored papers 4
Jeffrey L Wrana
Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital
Co-authored papers 3
Benjamin L Ebert
Co-authored papers 3
Gary D Bader
University of Toronto
Co-authored papers 3
Todd R Golub
Broad Institute of MIT and Harvard
Co-authored papers 3
Björn Nilsson
Co-authored papers 3
Jun Lu
Yale University
Co-authored papers 2
Alessandro Datti
University of Perugia
Co-authored papers 2
Nada Jabado
McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
Co-authored papers 2
Sean P McDermott
Co-authored papers 2
Jay S Wunder
University of Toronto
Co-authored papers 2
Lap-Chee Tsui
The University of Hong Kong
Co-authored papers 2
Stephen W Scherer
The Hospital for Sick Children
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Sergei Doulatov
University of Washington
Co-authored papers 2
Peter W Zandstra
Co-authored papers 2
Luigi Naldini
Vita-Salute San Raffaele University
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Ruth Isserlin
University of Toronto
Co-authored papers 2
Charles G Mullighan
St Jude Children's Research Hospital
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Marie-Jos??e H??bert
Universite de Montreal
Co-authored papers 1
Daniel Sinnett
Sainte-Justine University Hospital Research Center
Co-authored papers 1
Hamid Nikbakht
Co-authored papers 1
Anna Y Lee
Ontario Institute for Cancer Research
Co-authored papers 1
Gregory Armaos
Departement de pharmacologie et physiologie, Universite de Montreal
Co-authored papers 1
Stanley Pounds
St. Jude Children's Research Hospital.
Co-authored papers 1
Levi Waldron
City University of New York School of Public Health
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William E Evans
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Release 1.2