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Author Details

Tobias C Walther
Harvard T. H. Chan School of Public Health
1999
119
62
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36096640Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum.Cold Spring Harb Perspect Biol2023
36096640Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum.Cold Spring Harb Perspect Biol2023
37150040Structure and function of lipid droplet assembly complexes.Curr Opin Struct Biol2023
37316513The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification.Nat Commun2023
36805337Fitm2 is required for ER homeostasis and normal function of murine liver.J Biol Chem2023
37248213Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.Nat Commun2023
37316513The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification.Nat Commun2023
37150040Structure and function of lipid droplet assembly complexes.Curr Opin Struct Biol2023
37248213Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.Nat Commun2023
36805337Fitm2 is required for ER homeostasis and normal function of murine liver.J Biol Chem2023
34583871The CYTOLD and ERTOLD pathways for lipid droplet-protein targeting.Trends Biochem Sci2022
35583926Seipin transmembrane segments critically function in triglyceride nucleation and lipid droplet budding from the membrane.Elife2022
36207292Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.Nat Commun2022
34990551Key Factors Governing Initial Stages of Lipid Droplet Formation.J Phys Chem B2022
35210614Seipin forms a flexible cage at lipid droplet formation sites.Nat Struct Mol Biol2022
35134345The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology.Dev Cell2022
34583871The CYTOLD and ERTOLD pathways for lipid droplet-protein targeting.Trends Biochem Sci2022
35583926Seipin transmembrane segments critically function in triglyceride nucleation and lipid droplet budding from the membrane.Elife2022
36207292Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.Nat Commun2022
35210614Seipin forms a flexible cage at lipid droplet formation sites.Nat Struct Mol Biol2022
34990551Key Factors Governing Initial Stages of Lipid Droplet Formation.J Phys Chem B2022
35134345The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology.Dev Cell2022
33463550The power of two: lessons from a scientific partnership.J Clin Invest2021
33593792Conditional targeting of phosphatidylserine decarboxylase to lipid droplets.Biol Open2021
33529166Combined immunodeficiency due to a mutation in the γ1 subunit of the coat protein I complex.J Clin Invest2021
33463550The power of two: lessons from a scientific partnership.J Clin Invest2021
34732896Publisher Correction: An open-access volume electron microscopy atlas of whole cells and tissues.Nature2021
33593792Conditional targeting of phosphatidylserine decarboxylase to lipid droplets.Biol Open2021
33529166Combined immunodeficiency due to a mutation in the γ1 subunit of the coat protein I complex.J Clin Invest2021
34732896Publisher Correction: An open-access volume electron microscopy atlas of whole cells and tissues.Nature2021
32345721Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant <i>wobbler</i> mice, a model of motor neuron degeneration.Proc Natl Acad Sci U S A2020
32433611Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme.Nature2020
32023484Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression.Mol Cell2020
32345721Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant <i>wobbler</i> mice, a model of motor neuron degeneration.Proc Natl Acad Sci U S A2020
33147469Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis.Cell Rep2020
32915949FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis.J Cell Biol2020
33176155A Systematic Protein Turnover Map for Decoding Protein Degradation.Cell Rep2020
32730754Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting.Dev Cell2020
32023484Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression.Mol Cell2020
33176155A Systematic Protein Turnover Map for Decoding Protein Degradation.Cell Rep2020
33147469Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis.Cell Rep2020
32915949FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis.J Cell Biol2020
32730754Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting.Dev Cell2020
32433611Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme.Nature2020
30527540Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment.Mol Cell2019
31708432LDAF1 and Seipin Form a Lipid Droplet Assembly Complex.Dev Cell2019
30527540Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment.Mol Cell2019
31505174Un-phased: Lipid Droplets Modulate the Bioavailability of Antibiotics.Dev Cell2019
31227602Genome wide analysis of 3' UTR sequence elements and proteins regulating mRNA stability during maternal-to-zygotic transition in zebrafish.Genome Res2019
31081165Hepatocyte Deletion of Triglyceride-Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice.Hepatology2019
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Collaborators

Robert V Farese
Harvard T.H. Chan School of Public Health
Co-authored papers 66
Florian Fr??hlich
Osnabruck University Department of Biology/Chemistry Bioanalytical Chemistry section
Co-authored papers 19
Chandramohan Chitraju
Co-authored papers 11
Zon Weng Lai
Co-authored papers 10
Matthias Mann
Max-Planck Institute of Biochemistry
Co-authored papers 10
Natalie Krahmer
Co-authored papers 9
Peter Walter
University of California san francisco
Co-authored papers 8
Niklas Mejhert
Karolinska Institutet
Co-authored papers 8
Pablo S Aguilar
Instituto de Fisiologia
Co-authored papers 6
Sebastian Boland
Co-authored papers 6
Gregory A Voth
Co-authored papers 5
Maofu Liao
Harvard Medical School
Co-authored papers 5
Christer S Ejsing
VILLUM Center for Bioanalytical Sciences, University of Southern Denmark
Co-authored papers 5
Michael Rehman
Institute of Biochemistry, Friedrich-Alexander-University of Erlangen-Nurnberg
Co-authored papers 4
J. Wade Harper
Harvard Medical School
Co-authored papers 3
Natasza E Zi????kowska
Tonix Pharmaceuticals Inc
Co-authored papers 3
Eric J Huang
University of California san francisco
Co-authored papers 3
Lena Karotki
Max Planck Institute of Biochemistry
Co-authored papers 3
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 3
Christopher G Burd
Yale School of Medicine
Co-authored papers 2
Michael Shales
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 2
J??rgen Cox
Max-Planck Institute of Biochemistry
Co-authored papers 2
Juha T Huiskonen
Institute of Biotechnology, University of Helsinki
Co-authored papers 2
Michal A Surma
Lukasiewicz Research Network-PORT Polish Center for Technology Development
Co-authored papers 2
Chunaram Choudhary
The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Co-authored papers 2
Benjamin F Cravatt
Scripps Research Institute
Co-authored papers 2
Frank DiMaio
University of Washington
Co-authored papers 2
Leena Kuruvilla
Co-authored papers 2
Dorothea Fiedler
Leibniz Forschungsinstitut fur Molekulare Pharmakologie (FMP)
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Release 1.2