Author details

Full Name

TÃµnu Esko

Affiliation

ORCID

Career Start Year

2009

Papers

307

H Index

108

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37034709	Untargeted metabolomics profiling in pediatric patients and adult populations indicates a connection between lipid imbalance and epilepsy.	medRxiv	2023
37679551	Author Correction: Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.	Nat Immunol	2023
38028628	Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.	Front Genet	2023
37923823	HLA allele-calling using multi-ancestry whole-exome sequencing from the UK Biobank identifies 129 novel associations in 11 autoimmune diseases.	Commun Biol	2023
37794016	European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.	Nat Commun	2023
37563310	Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.	Nat Immunol	2023
37873414	GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets.	medRxiv	2023
37872160	Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease.		2023
37688361	A pilot genome-wide association study meta-analysis of gastroparesis.	United European Gastroenterol J	2023
36717893	Impact of the gut microbiota and associated metabolites on cardiometabolic traits, chronic diseases and human longevity: a Mendelian randomization study.		2023
36653562	FinnGen provides genetic insights from a well-phenotyped isolated population.	Nature	2023
36829046	Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population.	Nature	2023
36653343	Genome-wide screen of otosclerosis in population biobanks: 27 loci and shared associations with skeletal structure.	Nat Commun	2023
37079300	Overlap of Genetic Loci for Central Serous Chorioretinopathy With Age-Related Macular Degeneration.	JAMA Ophthalmol	2023
36882394	OTTERS: a powerful TWAS framework leveraging summary-level reference data.	Nat Commun	2023
37503126	Understanding the genetic complexity of puberty timing across the allele frequency spectrum.	medRxiv	2023
35073279	A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk.	Aging	2022
35396580	Mapping genomic loci implicates genes and synaptic biology in schizophrenia.	Nature	2022
36249462	Mendelian randomization prioritizes abdominal adiposity as anÂ independent causal factor for liver fat accumulation and cardiometabolic diseases.		2022
35396579	Rare coding variants in ten genes confer substantial risk for schizophrenia.	Nature	2022
35653391	Using genetic variation to disentangle the complex relationship between food intake and health outcomes.	PLoS Genet	2022
35387486	Genetic Landscape of the ACE2 Coronavirus Receptor.	Circulation	2022
36093044	Genetic association and Mendelian randomization for hypothyroidism highlight immune molecular mechanisms.	iScience	2022
35697829	Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.	Commun Biol	2022
35629944	Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease.	Metabolites	2022
35938029	Precise, Genotype-First Breast Cancer Prevention: Experience With Transferring Monogenic Findings From a Population Biobank to the Clinical Setting.	Frontiers in Genetics	2022
35928446	Do Biobank Recall Studies Matter? Long-Term Follow-Up of Research Participants With Familial Hypercholesterolemia.	Frontiers in Genetics	2022
36477530	Genetic diversity fuels gene discovery for tobacco and alcohol use.	Nature	2022
34099189	Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.	Biol Psychiatry	2022
34378841	A survey of functional dyspepsia in 361,360 individuals: Phenotypic and genetic cross-disease analyses.	Neurogastroenterol Motil	2022
34414346	Developing the building blocks to elucidate the impact of the urban exposome on cardiometabolic-pulmonary disease: The EU EXPANSE project.	Environ Epidemiol	2021
32064741	Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.	Addict Biol	2021
33972266	Stratification of Type 2 Diabetes by Age of Diagnosis in the UK Biobank Reveals Subgroup-Specific Genetic Associations and Causal Risk Profiles.		2021
33859359	Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure.	Mol Psychiatry	2021
33691233	Genome-wide analyses of smoking behaviors in schizophrenia: Findings from the Psychiatric Genomics Consortium.	J Psychiatr Res	2021
33851187	Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19.	medRxiv	2021
34002096	Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.	Nat Genet	2021
33888516	Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease.	Gut	2021
33727701	Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.	Nat Genet	2021
33558525	Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.	Nat Commun	2021
33710309	Multivariate genome-wide analysis of immunoglobulin G N-glycosylation identifies new loci pleiotropic with immune function.	Human Molecular Genetics	2021
32989287	Genome-wide association study identifies 48 common genetic variants associated with handedness.	Nat Hum Behav	2021
33230308	Genotype-first approach to the detection of hereditary breast and ovarian cancer risk, and effects of risk disclosure to biobank participants.	European Journal of Human Genetics	2021
33402679	Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.	Nat Commun	2021
33268560	Association of Circulating Metabolites in Plasma or Serum and Risk of Stroke: Meta-analysis From 7 Prospective Cohorts.	Neurology	2021
34465810	Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study.	Scientific Reports	2021
34790224	Mendelian Randomization Identifies the Potential Causal Impact of Dietary Patterns on Circulating Blood Metabolites.	Frontiers in Genetics	2021
34611364	A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response.	Nat Genet	2021
34841290	Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease.	Cell Reports Medicine	2021
34493871	Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation.	Nat Genet	2021