Skip to Main Content

Author Details

Carol L Farr
Joint Center for Structural Genomics
1994
61
26
PMIDPaper TitleJournal TitlePublished Year
27050129UHM-ULM interactions in the RBM39-U2AF65 splicing-factor complex.Acta Crystallogr D Struct Biol2016
26650892Structure and functional characterization of a bile acid 7α dehydratase BaiE in secondary bile acid synthesis.Proteins2016
27062925A Distinct Type of Pilus from the Human Microbiome.Cell2016
25825768Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells.Proc Natl Acad Sci U S A2015
26374125Insights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 Domains.mBio2015
23836456Structural and functional characterization of BaiA, an enzyme involved in secondary bile acid synthesis in human gut microbe.Proteins2014
25286848Structural analysis of arabinose-5-phosphate isomerase from Bacteroides fragilis and functional implications.Acta Crystallogr D Biol Crystallogr2014
25044324Crystal structures of three representatives of a new Pfam family PF14869 (DUF4488) suggest they function in sugar binding/uptake.Protein Sci2014
24051416Structures of a bifunctional cell wall hydrolase CwlT containing a novel bacterial lysozyme and an NlpC/P60 DL-endopeptidase.J Mol Biol2014
24174223Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family.Proteins2014
23852666Crystal structure of a member of a novel family of dioxygenases (PF10014) reveals a conserved cupin fold and active site.Proteins2014
23572527Structure and function of the DUF2233 domain in bacteria and in the human mannose 6-phosphate uncovering enzyme.J Biol Chem2013
23729397Muscle-specific overexpression of the catalytic subunit of DNA polymerase γ induces pupal lethality in Drosophila melanogaster.Arch Insect Biochem Physiol2013
22984442Structure of a novel winged-helix like domain from human NFRKB protein.PLoS One2012
21445265Structure and function of the first full-length murein peptide ligase (Mpl) cell wall recycling protein.PLoS One2011
21799754Structural and sequence analysis of imelysin-like proteins implicated in bacterial iron uptake.PLoS One2011
21538547Crystal structure of a metal-dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activity.Proteins2011
20010955Ischemic preconditioning regulates expression of microRNAs and a predicted target, MeCP2, in mouse cortex.J Cereb Blood Flow Metab2010
20836087The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu.Protein Sci2010
20869368Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids.J Mol Biol2010
20944232Structure of the γ-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-γ-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944230Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved α+β core domain and an auxiliary C-terminal treble-clef zinc finger.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944225Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944224Structure of Bacteroides thetaiotaomicron BT2081 at 2.05⿿ÿ resolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolism.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944223A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2⿿ÿ resolution.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944222Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944221The structure of BVU2987 from Bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory function.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944219The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-fold.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944209Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944208The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20153822Functional analysis of H. sapiens DNA polymerase gamma spacer mutation W748S with and without common variant E1143G.Biochim Biophys Acta2010
20399190Structure of a virulence regulatory factor CvfB reveals a novel winged helix RNA binding module.Structure2010
19913036Bacterial pleckstrin homology domains: a prokaryotic origin for the PH domain.J Mol Biol2010
19173316Crystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 A resolution.Proteins2009
19567872Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes.J Biol Chem2009
17999718Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion.J Neurochem2008
18593709Physiological and biochemical defects in carboxyl-terminal mutants of mitochondrial DNA helicase.J Biol Chem2008
17324440Modular architecture of the hexameric human mitochondrial DNA helicase.J Mol Biol2007
18314716Drosophila melanogaster as a model system to study mitochondrial biology.Methods Mol Biol2007
16574152A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase.J Mol Biol2006
15917273Functional defects due to spacer-region mutations of human mitochondrial DNA polymerase in a family with an ataxia-myopathy syndrome.Hum Mol Genet2005
14754882Physiological and biochemical defects in functional interactions of mitochondrial DNA polymerase and DNA-binding mutants of single-stranded DNA-binding protein.J Biol Chem2004
15447677Proteomic analysis of native metabotropic glutamate receptor 5 protein complexes reveals novel molecular constituents.J Neurochem2004
14695827Three-dimensional quantitative structure-activity relationship modeling of cocaine binding by a novel human monoclonal antibody.J Med Chem2004
12763827Three-dimensional structure-activity relationship modeling of digoxin inhibition and docking to Na+,K+-ATPase.Ann N Y Acad Sci2003
11917141The accessory subunit of DNA polymerase gamma is essential for mitochondrial DNA maintenance and development in Drosophila melanogaster.Proc Natl Acad Sci U S A2002
12109909Three-dimensional quantitative structure-activity relationship analysis of ligand binding to human sequence antidigoxin monoclonal antibodies using comparative molecular field analysis.J Med Chem2002
12013803Purification strategies for Drosophila mtDNA replication proteins in native and recombinant form. Mitochondrial single-stranded DNA-binding protein.Methods Mol Biol2002
12013802Purification strategies for Drosophila mtDNA replication proteins in native and recombinant form. DNA polymerase gamma.Methods Mol Biol2002
11802712Three-dimensional quantitative structure-activity relationship study of the inhibition of Na(+),K(+)-ATPase by cardiotonic steroids using comparative molecular field analysis.Biochemistry2002
  • 1 - 50 of 61

Recommended Authors

Washington University
Career Start Year 2007
Number of shared co-authors 1
Karolinska Institutet
Career Start Year 2000
Number of shared co-authors 2
UT Southwestern Medical Center
Career Start Year 1997
Number of shared co-authors 0
Weizmann Institute of Science
Career Start Year 1996
Number of shared co-authors 2
Nankai University
Career Start Year 1995
Number of shared co-authors 3
Weizmann Institute of Science
Career Start Year 1995
Number of shared co-authors 2
Max-Planck-Institute of Biochemistry
Career Start Year 1995
Number of shared co-authors 0
College of Materials Science and Engineering, Hunan University
Career Start Year 1994
Number of shared co-authors 2
University of Texas Southwestern Medical Center
Career Start Year 1993
Number of shared co-authors 1
University of Toronto
Career Start Year 1989
Number of shared co-authors 4
Karolinska Institutet, BioClinicum J6
Career Start Year 1989
Number of shared co-authors 4
Columbia University
Career Start Year 1988
Number of shared co-authors 4
Albert Einstein College of Medicine
Career Start Year 1988
Number of shared co-authors 5
Columbia University
Career Start Year 1986
Number of shared co-authors 2
University of Miami Miller School of Medicine
Career Start Year 1986
Number of shared co-authors 2
University of Toronto
Career Start Year 1984
Number of shared co-authors 5
Structural Genomics Consortium Karolinska Institute Stockholm Sweden.
Career Start Year 1984
Number of shared co-authors 2
Weizmann Institute of Science
Career Start Year 1983
Number of shared co-authors 2
Yokohama City University
Career Start Year 1982
Number of shared co-authors 1
The State University of New Jersey
Career Start Year 1982
Number of shared co-authors 6
Yale-NUS College Singapore
Career Start Year 1981
Number of shared co-authors 1
Max-Delbruck-Center for Molecular Medicine in the Helmholtz Association (MDC)
Career Start Year 1980
Number of shared co-authors 2
Shinshu University School of Medicine
Career Start Year 1979
Number of shared co-authors 3
Center for Structural Biology of Infectious Diseases, University of Chicago
Career Start Year 1979
Number of shared co-authors 9
University College London
Career Start Year 1977
Number of shared co-authors 0
College of Agricultural and Life Sciences, University of Wisconsin-Madison
Career Start Year 1976
Number of shared co-authors 0
University of Rome 'Tor Vergata'
Career Start Year 1976
Number of shared co-authors 0
Rice University
Career Start Year 1974
Number of shared co-authors 2
University of California berkeley
Career Start Year 1967
Number of shared co-authors 3
University of California San Francisco
Career Start Year 1965
Number of shared co-authors 3

Collaborators

Merck & Co., Inc.
Co-authored papers 32
Joint Center for Structural Genomics
Co-authored papers 32
The Scripps Research Institute, USA The Skaggs Institute for Chemical Biology
Co-authored papers 31
Joint Center for Structural Genomics
Co-authored papers 31
Accelero Biostructures Inc., USA XPose Therapeutics Inc.
Co-authored papers 30
University of California Riverside
Co-authored papers 30
Rice University
Co-authored papers 27
Joint Center for Structural Genomics
Co-authored papers 25
University of California Riverside School of Medicine
Co-authored papers 24
Argonne National Laboratory
Co-authored papers 23
Merck & Co., Inc.
Co-authored papers 21
Joint Center for Structural Genomics
Co-authored papers 21
Accelero Biostructures Inc., USA XPose Therapeutics Inc.
Co-authored papers 20
Joint Center for Structural Genomics
Co-authored papers 19
Incyte Corporation
Co-authored papers 16
Co-authored papers 16
The Scripps Research Institute
Co-authored papers 16
University of Lucknow
Co-authored papers 16
Joint Center for Structural Genomics, Sanford-Burnham Medical Research Institute
Co-authored papers 16
Celgene/Bristol-Myers Squibb Corporation
Co-authored papers 15
Bridge Institute, University of Southern California
Co-authored papers 15
Co-authored papers 15
Regeneron Pharmaceuticals, Inc.
Co-authored papers 14
Cardiovascular Institute, Stanford University School of Medicine
Co-authored papers 14
Brown University
Co-authored papers 14
Joint Center for Structural Genomics ( http:/www.jcsg.org )
Co-authored papers 14
Genomics Institute of the Novartis Research Foundation
Co-authored papers 14
University of California San Francisco
Co-authored papers 14
Co-authored papers 14
Institute of Science, Banaras Hindu University
Co-authored papers 14