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Author Details

Kelly E Glajch
Neurodegenerative Diseases Research Unit
2006
19
15
Timothy Clark (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37567894Transient exposure to rotenone causes degeneration and progressive parkinsonian motor deficits, neuroinflammation, and synucleinopathy.NPJ Parkinsons Dis2023
35610264Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein.NPJ Parkinsons Dis2022
33443159The Parkinson's disease-associated gene ITPKB protects against α-synuclein aggregation by regulating ER-to-mitochondria calcium release.Proc Natl Acad Sci U S A2021
34326260Wild-type GBA1 increases the α-synuclein tetramer-monomer ratio, reduces lipid-rich aggregates, and attenuates motor and cognitive deficits in mice.Proc Natl Acad Sci U S A2021
32369618Lipocalin-2 is increased in amyotrophic lateral sclerosis.Muscle Nerve2020
33315879SVA insertion in X-linked Dystonia Parkinsonism alters histone H3 acetylation associated with TAF1 gene.PLoS One2020
30054496Hippo Signaling Pathway Dysregulation in Human Huntington's Disease Brain and Neuronal Stem Cells.Sci Rep2018
27194328Npas1+ Pallidal Neurons Target Striatal Projection Neurons.J Neurosci2016
27716798MicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis.PLoS One2016
25813218Epigenetic Mechanisms Involved in Huntington's Disease Pathogenesis.J Huntingtons Dis2015
26311767Parvalbumin+ Neurons and Npas1+ Neurons Are Distinct Neuron Classes in the Mouse External Globus Pallidus.J Neurosci2015
22178078Sensorimotor assessment of the unilateral 6-hydroxydopamine mouse model of Parkinson's disease.Behav Brain Res2012
22764222Strain-specific regulation of striatal phenotype in Drd2-eGFP BAC transgenic mice.J Neurosci2012
21076425HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease.Nat Neurosci2011
19805039Infection of neurons and encephalitis after intracranial inoculation of herpes simplex virus requires the entry receptor nectin-1.Proc Natl Acad Sci U S A2009
1860809150bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis.Amyotroph Lateral Scler2008
17409194Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models.Hum Mol Genet2007
17357802Phosphorylation and cleavage of tau in non-AD tauopathies.Acta Neuropathol2007
16442295Decreased association of the transcription factor Sp1 with genes downregulated in Huntington's disease.Neurobiol Dis2006
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Collaborators

Ghazaleh Sadri-Vakili
Sean M. Healey & AMG Center for ALS at Mass General
Co-authored papers 8
Pavel Osten
Co-authored papers 3
Jang-Ho J Cha
Novartis Institutes for Biomedical Research
Co-authored papers 3
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Pfizer Neuroscience and Pain Research Unit, Pfizer Ltd.
Co-authored papers 2
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CHDI Management/CHDI Foundation
Co-authored papers 2
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Sean M Healey & AMG Center for ALS, Massachusetts General Hospital
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B??reng??re Bouzou
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Kay Gr??newald
Leibniz Institute of Virology
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Guy A Rouleau
McGill University, Canada Montreal Neurological Institute and Hospital
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Inc. University Avenue
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
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Shaun Purcell
Brigham and Women's Hospital
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Sarah J Kopp
Northwestern University Feinberg School of Medicine
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Mee-Ohk Kim
University of California san francisco
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Derek P DiRocco
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 1
Nathaniel Heintz
Howard Hughes Medical Institute, The Rockefeller University
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Timothy Clark (CM4AI)
University of Virginia
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Pamela J Shaw
Sheffield Institute for Translational Neuroscience, University of Sheffield
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Ryan P Overland
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Prianka Chawla
Center for Regenerative Therapies Dresden, Technische Universitat Dresden
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Marcy E MacDonald
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Tim Clark
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Caroline Hayward
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Release 1.2