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Author Details

Maxwell R Mumbach
Broad Institute of MIT and Harvard
2013
32
26
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34826345IRF3 inhibits IFN-γ-mediated restriction of intracellular pathogens in macrophages independently of IFNAR.J Leukoc Biol2022
35999210KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress.Nat Commun2022
34285077Dynamic chromatin regulatory landscape of human CAR T cell exhaustion.Proc Natl Acad Sci U S A2021
32499651A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by T<sub>reg</sub> cells.Nature2020
33106633Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer's and Parkinson's diseases.Nat Genet2020
33052334Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection.bioRxiv2020
32763147Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates.Dev Cell2020
30315781Enhancer Connectome Nominates Target Genes of Inherited Risk Variants from Inflammatory Skin Disorders.J Invest Dermatol2019
31672989GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways.Nat Commun2019
31375813Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion.Nat Biotechnol2019
30709738A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells.Immunity2019
31133759HiChIRP reveals RNA-associated chromosome conformation.Nat Methods2019
30745086Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques.Mol Cell2019
29686426Transcript-indexed ATAC-seq for precision immune profiling.Nat Med2018
29899441Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation.Nature2018
30397335Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment.Nat Genet2018
30361341The chromatin accessibility landscape of primary human cancers.Science2018
29731168Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element.Cell2018
29743654Expression of the transcription factor ZBTB46 distinguishes human histiocytic disorders of classical dendritic cell origin.Mod Pathol2018
28846090An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues.Nat Methods2017
28945252Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.Nat Genet2017
28854172Discovery of stimulation-responsive immune enhancers with CRISPR activation.Nature2017
28805829Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation.Nat Genet2017
26766114Transcriptome-wide interrogation of RNA secondary structure in living cells with icSHAPE.Nat Protoc2016
27643841HiChIP: efficient and sensitive analysis of protein-directed genome architecture.Nat Methods2016
25745177Immunogenetics. Dynamic profiling of the protein life cycle in response to pathogens.Science2015
25874869Shade avoidance components and pathways in adult plants revealed by phenotypic profiling.PLoS Genet2015
24981863Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites.Cell Rep2014
25219674Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation of ncRNA and mRNA.Cell2014
23380664LeafJ: an ImageJ plugin for semi-automated leaf shape measurement.J Vis Exp2013
23825970Transcriptome-wide mapping of 5-methylcytidine RNA modifications in bacteria, archaea, and yeast reveals m5C within archaeal mRNAs.PLoS Genet2013
24269006High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis.Cell2013
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Collaborators

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Rowan University School of Osteopathic Medicine
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Vanderbilt-Ingram Cancer Center, Vanderbilt University
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University of California San Francisco
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Broad Institute of MIT and Harvard
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Massachusetts General Hospital
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Harvard University, USA Broad Institute, USA Harvard Stem Cell Institute
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