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Author Details

Patricia A Pioli
Dartmouth Geisel School of Medicine
1994
44
27
PMIDPaper TitleJournal TitlePublished Year
35946522Human dermal fibroblast-derived exosomes induce macrophage activation in systemic sclerosis.Rheumatology (Oxford)2023
37577680CDDO-Methyl Ester Inhibits BRAF Inhibitor Resistance and Remodels the Myeloid Compartment in BRAF-mutant Melanoma.bioRxiv2023
35265066T Cells and CDDO-Me Attenuate Immunosuppressive Activation of Human Melanoma-Conditioned Macrophages.Front Immunol2022
35212485Self-Assembled Human Skin Equivalents Model Macrophage Activation of Cutaneous Fibrogenesis in Systemic Sclerosis.Arthritis Rheumatol2022
32134204Profibrotic Activation of Human Macrophages in Systemic Sclerosis.Arthritis Rheumatol2020
31705627Systemic Sclerosis Dermal Fibroblasts Induce Cutaneous Fibrosis Through Lysyl Oxidase-like 4: New Evidence From Three-Dimensional Skin-like Tissues.Arthritis Rheumatol2020
32300202CDDO-Me Alters the Tumor Microenvironment in Estrogen Receptor Negative Breast Cancer.Sci Rep2020
30728065Microbiome dysbiosis is associated with disease duration and increased inflammatory gene expression in systemic sclerosis skin.Arthritis Res Ther2019
31123840Macrophages in Systemic Sclerosis: Novel Insights and Therapeutic Implications.Curr Rheumatol Rep2019
29391252Mycophenolate Mofetil Treatment of Systemic Sclerosis Reduces Myeloid Cell Numbers and Attenuates the Inflammatory Gene Signature in Skin.J Invest Dermatol2018
30028389The Stress Hormone Cortisol Enhances Interferon-Ï¿-Mediated Proinflammatory Responses of Human Immune Cells.Anesth Analg2018
28330499A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis.Genome Med2017
28254412Bromodomain inhibitors, JQ1 and I-BET 762, as potential therapies for pancreatic cancer.Cancer Lett2017
26918785CDDO-Me Redirects Activation of Breast Tumor Associated Macrophages.PLoS One2016
27659181The triterpenoid CDDO-imidazolide reduces immune cell infiltration and cytokine secretion in the KrasG12D;Pdx1-Cre (KC) mouse model of pancreatic cancer.Carcinogenesis2016
26790757Glucocorticoids enhance the in vivo migratory response of human monocytes.Brain Behav Immun2016
25569146Systems level analysis of systemic sclerosis shows a network of immune and profibrotic pathways connected with genetic polymorphisms.PLoS Comput Biol2015
26223504Gene expression profiling offers insights into the role of innate immune signaling in SSc.Semin Immunopathol2015
23042302The combination of the histone deacetylase inhibitor vorinostat and synthetic triterpenoids reduces tumorigenesis in mouse models of cancer.Carcinogenesis2013
22882270A subset of human uterine endometrial macrophages is alternatively activated.Am J Reprod Immunol2012
22013396Cortisol exerts bi-phasic regulation of inflammation in humans.Dose Response2011
20351193Estradiol suppresses NF-kappa B activation through coordinated regulation of let-7a and miR-125b in primary human macrophages.J Immunol2010
19086992Human uterine NK cells interact with uterine macrophages via NKG2D upon stimulation with PAMPs.Am J Reprod Immunol2009
19885996Pretreatment with stress cortisol enhances the human systemic inflammatory response to bacterial endotoxin.Crit Care Med2009
19440537Estradiol regulates expression of estrogen receptor ERalpha46 in human macrophages.PLoS One2009
19406482Functional expression of pattern recognition receptors in tissues of the human female reproductive tract.J Reprod Immunol2009
18550855PILAR is a novel modulator of human T-cell expansion.Blood2008
18728002Estradiol regulates MICA expression in human endometrial cells.Clin Immunol2008
18931239In vivo exposure to high or low cortisol has biphasic effects on inflammatory response pathways of human monocytes.Anesth Analg2008
17164428Up-regulation of human monocyte CD163 upon activation of cell-surface Toll-like receptors.J Leukoc Biol2007
17947704Estradiol attenuates lipopolysaccharide-induced CXC chemokine ligand 8 production by human peripheral blood monocytes.J Immunol2007
16709823Lipopolysaccharide-induced IL-1 beta production by human uterine macrophages up-regulates uterine epithelial cell expression of human beta-defensin 2.J Immunol2006
16799153Pivotal advance: activation of cell surface Toll-like receptors causes shedding of the hemoglobin scavenger receptor CD163.J Leukoc Biol2006
16048557Innate and adaptive immunity in female genital tract: cellular responses and interactions.Immunol Rev2005
16272305IL-1beta-mediated proinflammatory responses are inhibited by estradiol via down-regulation of IL-1 receptor type I in uterine epithelial cells.J Immunol2005
15136587TGF-beta regulation of human macrophage scavenger receptor CD163 is Smad3-dependent.J Leukoc Biol2004
15385480Differential expression of Toll-like receptors 2 and 4 in tissues of the human female reproductive tract.Infect Immun2004
15075364Cross-linking of FcgammaR triggers shedding of the hemoglobin-haptoglobin scavenger receptor CD163.J Leukoc Biol2004
12107167Lactate dehydrogenase is an AU-rich element-binding protein that directly interacts with AUF1.J Biol Chem2002
12377940Endotoxin induces rapid metalloproteinase-mediated shedding followed by up-regulation of the monocyte hemoglobin scavenger receptor CD163.J Leukoc Biol2002
11517223The von Hippel-Lindau protein interacts with heteronuclear ribonucleoprotein a2 and regulates its expression.J Biol Chem2001
9816243Retroviral transfer and expression of the human multiple drug resistance (MDR) gene in peripheral blood progenitor cells.Clin Cancer Res1996
22358644Transfer and expression of the human multiple drug resistance gene as potential human gene therapy.Cytotechnology1995
7520768Transfer and expression of the human multiple drug resistance gene in human CD34+ cells.Blood1994
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Collaborators

Geisel School of Medicine at Dartmouth
Co-authored papers 11
Yale School of Medicine
Co-authored papers 5
Geisel School of Medicine at Dartmouth
Co-authored papers 4
Geisel School of Medicine at Dartmouth
Co-authored papers 4
Alex's Lemonade Stand Foundation
Co-authored papers 3
Co-authored papers 3
Co-authored papers 2
Larner College of Medicine, University of Vermont
Co-authored papers 2
Dartmouth College Geisel School of Medicine, Princeton University, University of Colorado Anschutz Medical Campus, University of Pennsylvania Perelman School of Medicine
Co-authored papers 2
Columbia University
Co-authored papers 1