|
| 37098540 | MYC drives platinum resistant SCLC that is overcome by the dual PI3K-HDAC inhibitor fimepinostat. | J Exp Clin Cancer Res | 2023 |
| 37845394 | Ligand-dependent hedgehog signaling maintains an undifferentiated, malignant osteosarcoma phenotype. | Oncogene | 2023 |
| 34675406 | Lineage-restricted neoplasia driven by Myc defaults to small cell lung cancer when combined with loss of p53 and Rb in the airway epithelium. | Oncogene | 2022 |
| 35732702 | SILAC kinase screen identifies potential MASTL substrates. | Sci Rep | 2022 |
| 34973373 | Deletion of kif3a in CK19 positive cells leads to primary cilia loss, biliary cell proliferation and cystic liver lesions in TAA-treated mice. | Biochim Biophys Acta Mol Basis Dis | 2022 |
| 33983115 | A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma. | Elife | 2021 |
| 32568216 | Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog signaling. | J Clin Invest | 2020 |
| 33235907 | p53 and RB1 regulate Hedgehog responsiveness via autophagy-mediated ciliogenesis. | Mol Cell Oncol | 2020 |
| 30348992 | Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer. | Oncogene | 2019 |
| 31683879 | A Sexually Dimorphic Role for STAT3 in Sonic Hedgehog Medulloblastoma. | Cancers (Basel) | 2019 |
| 30898150 | Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer. | Breast Cancer Res | 2019 |
| 30833304 | ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer. | EMBO Mol Med | 2019 |
| 30936196 | Genomic stratification and liquid biopsy in a rare adrenocortical carcinoma (ACC) case, with dual lung metastases. | Cold Spring Harb Mol Case Stud | 2019 |
| 29277856 | A phase IIa study of HA-irinotecan, formulation of hyaluronic acid and irinotecan targeting CD44 in extensive-stage small cell lung cancer. | Invest New Drugs | 2018 |
| 30045976 | Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy. | Sci Transl Med | 2018 |
| 30042390 | Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer. | Nat Commun | 2018 |
| 30464171 | Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing. | Nat Commun | 2018 |
| 29743597 | MASTL overexpression promotes chromosome instability and metastasis in breast cancer. | Oncogene | 2018 |
| 29367758 | The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53. | Oncogene | 2018 |
| 28074012 | Reduced abundance of the E3 ubiquitin ligase E6AP contributes to decreased expression of the INK4/ARF locus in non-small cell lung cancer. | Sci Signal | 2017 |
| 28257959 | The Immune Microenvironment, Genome-wide Copy Number Aberrations, and Survival in Mesothelioma. | J Thorac Oncol | 2017 |
| 28187190 | Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease. | PLoS One | 2017 |
| 29176597 | In vivo evidence that RBM5 is a tumour suppressor in the lung. | Sci Rep | 2017 |
| 28650469 | A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma. | Oncogene | 2017 |
| 28646020 | MCAM Mediates Chemoresistance in Small-Cell Lung Cancer via the PI3K/AKT/SOX2 Signaling Pathway. | Cancer Res | 2017 |
| 28820907 | Positive regulatory interactions between YAP and Hedgehog signalling in skin homeostasis and BCC development in mouse skin in vivo. | PLoS One | 2017 |
| 28581526 | The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer. | Oncogene | 2017 |
| 27893707 | Blockade of the IL-6 trans-signalling/STAT3 axis suppresses cachexia in Kras-induced lung adenocarcinoma. | Oncogene | 2017 |
| 26920892 | Low-Dose Histone Deacetylase Inhibitor Treatment Leads to Tumor Growth Arrest and Multi-Lineage Differentiation of Malignant Rhabdoid Tumors. | Clin Cancer Res | 2016 |
| 27931239 | MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib. | Breast Cancer Res | 2016 |
| 27669108 | Immunotherapy for malignant mesothelioma: reality check. | Expert Rev Anticancer Ther | 2016 |
| 27780599 | Calretinin but not caveolin-1 correlates with tumour histology and survival in malignant mesothelioma. | Pathology | 2016 |
| 27417119 | Mechanisms regulating phosphatase specificity and the removal of individual phosphorylation sites during mitotic exit. | Bioessays | 2016 |
| 27551510 | Mitochondrial DNA plasticity is an essential inducer of tumorigenesis. | Cell Death Discov | 2016 |
| 26740067 | The mouse endometrium contains epithelial, endothelial and leucocyte populations expressing the stem cell marker telomerase reverse transcriptase. | Mol Hum Reprod | 2016 |
| 26872783 | PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells. | J Cell Sci | 2016 |
| 25125202 | Peptide receptor chemoradionuclide therapy in small cell carcinoma: from bench to bedside. | Eur J Nucl Med Mol Imaging | 2015 |
| 26270676 | Hedgehog Signaling in the Maintenance of Cancer Stem Cells. | Cancers (Basel) | 2015 |
| 26425664 | Dataset from the global phosphoproteomic mapping of early mitotic exit in human cells. | Data Brief | 2015 |
| 26371045 | The Evolution of Therapies in Non-Small Cell Lung Cancer. | Cancers (Basel) | 2015 |
| 26055452 | Global Phosphoproteomic Mapping of Early Mitotic Exit in Human Cells Identifies Novel Substrate Dephosphorylation Motifs. | Mol Cell Proteomics | 2015 |
| 25605927 | BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs. | Proc Natl Acad Sci U S A | 2015 |
| 25544756 | Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis. | Oncotarget | 2015 |
| 23978713 | The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury. | J Hepatol | 2014 |
| 25191746 | Genomic characterisation of small cell lung cancer patient-derived xenografts generated from endobronchial ultrasound-guided transbronchial needle aspiration specimens. | PLoS One | 2014 |
| 25152208 | Reply to: "The many faces of Hedgehog signalling in the liver: recent progress reveals striking cellular diversity and the importance of microenvironments". | J Hepatol | 2014 |
| 25083987 | Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia. | J Clin Invest | 2014 |
| 24762066 | Changes in aldehyde dehydrogenase-1 expression during neoadjuvant chemotherapy predict outcome in locally advanced breast cancer. | Breast Cancer Res | 2014 |
| 24887064 | Seminoma and embryonal carcinoma footprints identified by analysis of integrated genome-wide epigenetic and expression profiles of germ cell cancer cell lines. | PLoS One | 2014 |
| 24907066 | The Victorian Lung Cancer Registry pilot: improving the quality of lung cancer care through the use of a disease quality registry. | Lung | 2014 |