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Author Details

Sakshi Tomar
J. David Gladstone Institutes
2009
14
9
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36603024Nuclear accumulation of host transcripts during Zika Virus Infection.PLoS Pathog2023
35499461Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors.Mol Cancer Ther2022
34904202Engineering a Remedy to Modulate and Optimize Biopharmaceutical Properties of Rebamipide by Synthesizing New Cocrystal: In Silico and Experimental Studies.Pharm Res2021
31554802Low expression of RNA sensors impacts Zika virus infection in the lower female reproductive tract.Nat Commun2019
30576660A BAF'ling Approach to Curing HIV.Cell Chem Biol2018
30401782The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein.mBio2018
26190463Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4--The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS).Bioorg Med Chem2015
26055715Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS.J Biol Chem2015
24667706A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant.mBio2014
23231439Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease.J Med Chem2013
24080461Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding.Bioorg Med Chem Lett2013
24027335Chimeric exchange of coronavirus nsp5 proteases (3CLpro) identifies common and divergent regulatory determinants of protease activity.J Virol2013
22291906Structure-function studies of DNA binding domain of response regulator KdpE reveals equal affinity interactions at DNA half-sites.PLoS One2012
19923745Crystallization and preliminary X-ray diffraction analysis of the complex of Kunitz-type tamarind trypsin inhibitor and porcine pancreatic trypsin.Acta Crystallogr Sect F Struct Biol Cryst Commun2009
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Collaborators

Melanie Ott
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Co-authored papers 4
Krystal A Fontaine
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Co-authored papers 3
Mark R Denison
Vanderbilt University Medical Center
Co-authored papers 3
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University of California San Francisco
Co-authored papers 2
Mir M Khalid
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Steven Finkbeiner
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Co-authored papers 2
Kristoffer E Leon
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Camille R Simoneau
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Rachel L Graham
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Vineet D Menachery
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Eric F Donaldson
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Sudhakar Agnihothram
National Center for Toxicological Research
Co-authored papers 1
Ibraheem Ali
University of California los angeles
Co-authored papers 1
Ryan A Flynn
Boston Children's Hospital
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Lisa E Gralinski
University of North Carolina at Chapel Hill
Co-authored papers 1
Ralph S Baric
University of North Carolina
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Release 1.2