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Author Details

Eyal Akiva
University of California san francisco
2006
24
16
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
32956445Human SIRT1 Multispecificity Is Modulated by Active-Site Vicinity Substitutions during Natural Evolution.Mol Biol Evol2021
33674467Parallel molecular mechanisms for enzyme temperature adaptation.Science2021
34437092Revealing enzyme functional architecture via high-throughput microfluidic enzyme kinetics.Science2021
31072492Exploring the sequence, function, and evolutionary space of protein superfamilies using sequence similarity networks and phylogenetic reconstructions.Methods Enzymol2019
31074977Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer.Biochemistry2019
29184004A global view of structure-function relationships in the tautomerase superfamily.J Biol Chem2018
30052428Revealing Unexplored Sequence-Function Space Using Sequence Similarity Networks.Biochemistry2018
30097089Atlas of the Radical SAM Superfamily: Divergent Evolution of Function Using a "Plug and Play" Domain.Methods Enzymol2018
27812939Evaluating Functional Annotations of Enzymes Using the Gene Ontology.Methods Mol Biol2017
28365730Biocuration in the structure-function linkage database: the anatomy of a superfamily.Database (Oxford)2017
28342985Mast cells are directly activated by contact with cancer cells by a mechanism involving autocrine formation of adenosine and autocrine/paracrine signaling of the adenosine A3 receptor.Cancer Lett2017
29078300Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily.Proc Natl Acad Sci U S A2017
28605775Biocuration in the structure-function linkage database: the anatomy of a superfamily.Database (Oxford)2017
25654171[FeFe]-hydrogenase maturation: insights into the role HydE plays in dithiomethylamine biosynthesis.Biochemistry2015
26496596Evolutionary reprograming of protein-protein interaction specificity.Cell2015
24271399The Structure-Function Linkage Database.Nucleic Acids Res2014
24980702Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks.Elife2014
24756107Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere.PLoS Biol2014
22253583A dynamic view of domain-motif interactions.PLoS Comput Biol2012
22927804Prediction of mutational tolerance in HIV-1 protease and reverse transcriptase using flexible backbone protein design.PLoS Comput Biol2012
22190034Global landscape of HIV-human protein complexes.Nature2011
20802208Preferential use of protein domain pairs as interaction mediators: order and transitivity.Bioinformatics2010
18757736Built-in loops allow versatility in domain-domain interactions: lessons from self-interacting domains.Proc Natl Acad Sci U S A2008
17184549Evolutionary conservation of domain-domain interactions.Genome Biol2006
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Collaborators

University of California san francisco
Co-authored papers 15
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 7
University of California san francisco
Co-authored papers 6
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Co-authored papers 4
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 4
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Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 3
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 3
University of California San Francisco
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 2
University of California san francisco
Co-authored papers 2
Cue BioPharma Inc.
Co-authored papers 2
University of California san francisco
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 2
University of California san francisco
Co-authored papers 1
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California
Co-authored papers 1
University of Utah School of Medicine
Co-authored papers 1
Institute of Molecular Biosciences, Goethe University Frankfurt
Co-authored papers 1
Medical College of Wisconsin
Co-authored papers 1
Gladstone Institutes
Co-authored papers 1
University of Wisconsin
Co-authored papers 1
University of Texas Southwestern Medical Center
Co-authored papers 1
The University of Sydney
Co-authored papers 1
University of California San Francisco
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Complete Genomics Inc.
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University of California san francisco
Co-authored papers 1
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Roche Pharma
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Gwangju Institute of Science and Technology
Co-authored papers 1