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Author Details

Yan W Asmann
Mayo Clinic
2000
182
48
PMIDPaper TitleJournal TitlePublished Year
36672426AT-101 Enhances the Antitumor Activity of Lenalidomide in Patients with Multiple Myeloma.Cancers (Basel)2023
37803069Deconvolution reveals cell-type-specific transcriptomic changes in the aging mouse brain.Sci Rep2023
37662251Cell-specific crosstalk proteomics reveals cathepsin B signaling as a driver of glioblastoma malignancy near the subventricular zone.bioRxiv2023
37605285APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids.Stem Cell Res Ther2023
37036005LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4.JCI Insight2023
37333387Multiomic Analysis Identifies a High-Risk Metabolic and TME Depleted Signature that Predicts Early Clinical Failure in DLBCL.medRxiv2023
34724591Correction to: Apolipoprotein E regulates lipid metabolism and α⿿synuclein pathology in human iPSC⿿derived cerebral organoids.Acta Neuropathol2022
35801929Response to Mitr and Pollack.J Natl Cancer Inst2022
36419137Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to demyelination.Mol Neurodegener2022
36107206Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia.J Exp Med2022
35931322Assessment and Optimization of Explainable Machine Learning Models Applied to Transcriptomic Data.Genomics Proteomics Bioinformatics2022
36186441Network approaches for omics studies of neurodegenerative diseases.Front Genet2022
35915180Peripheral apoE4 enhances Alzheimer's pathology and impairs cognition by compromising cerebrovascular function.Nat Neurosci2022
34918030Shared brain transcriptomic signature in TDP-43 type A FTLD patients with or without GRN mutations.Brain2022
35299252Lower Exome Sequencing Coverage of Ancestrally African Patients in The Cancer Genome Atlas.J Natl Cancer Inst2022
34813500Alzheimer's disease and progressive supranuclear palsy share similar transcriptomic changes in distinct brain regions.J Clin Invest2022
32139889Targeting of inflammatory pathways with R2CHOP in high-risk DLBCL.Leukemia2021
33742076Inflation of tumor mutation burden by tumor-only sequencing in under-represented groups.NPJ Precis Oncol2021
33875655Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer's disease.Nat Commun2021
33709463Loss of Tmem106b leads to cerebellum Purkinje cell death and motor deficits.Brain Pathol2021
33897360ABCA7 Regulates Brain Fatty Acid Metabolism During LPS-Induced Acute Inflammation.Front Neurosci2021
33861770Impact of variant-level batch effects on identification of genetic risk factors in large sequencing studies.PLoS One2021
33747938Human Cerebrospinal Fluid Modulates Pathways Promoting Glioblastoma Malignancy.Front Oncol2021
34439202Role of PLEXIND1/TGFβ Signaling Axis in Pancreatic Ductal Adenocarcinoma Progression Correlates with the Mutational Status of <i>KRAS</i>.Cancers (Basel)2021
34586832<i>APOE3</i>-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia.Sci Transl Med2021
34453582Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids.Acta Neuropathol2021
34233962The Prognostic Role of MYC Structural Variants Identified by NGS and FISH in Multiple Myeloma.Clin Cancer Res2021
33953196Author Correction: APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids.Nat Commun2021
33249487Alpha 1-antichymotrypsin contributes to stem cell characteristics and enhances tumorigenicity of glioblastoma.Neuro Oncol2021
33321072Vascular ApoE4 Impairs Behavior by Modulating Gliovascular Function.Neuron2021
31600786Inherited variants at 3q13.33 and 3p24.1 are associated with risk of diffuse large B-cell lymphoma and implicate immune pathways.Hum Mol Genet2020
32024798APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid.Sci Transl Med2020
31665905ApoE (Apolipoprotein E) in Brain Pericytes Regulates Endothelial Function in an Isoform-Dependent Manner by Modulating Basement Membrane Components.Arterioscler Thromb Vasc Biol2020
33139712APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids.Nat Commun2020
32660529Deciphering cellular transcriptional alterations in Alzheimer's disease brains.Mol Neurodegener2020
32928256Correction to: Deciphering cellular transcriptional alterations in Alzheimer's disease brains.Mol Neurodegener2020
32753376Immune Responses and Risk of Triple-negative Breast Cancer: Implications for Higher Rates among African American Women.Cancer Prev Res (Phila)2020
32504082Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies.Brain2020
32179748The CCND1 c.870G risk allele is enriched in individuals of African ancestry with plasma cell dyscrasias.Blood Cancer J2020
32523802HLA class-I and class-II restricted neoantigen loads predict overall survival in breast cancer.Oncoimmunology2020
32176769Somatic selection distinguishes oncogenes and tumor suppressor genes.Bioinformatics2020
32199103Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways.Neuron2020
30335176NucMap: a database of genome-wide nucleosome positioning map across species.Nucleic Acids Res2019
31690660ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain.Proc Natl Acad Sci U S A2019
31471540Amplification of 9p24.1 in diffuse large B-cell lymphoma identifies a unique subset of cases that resemble primary mediastinal large B-cell lymphoma.Blood Cancer J2019
31287816Managing genomic variant calling workflows with Swift/T.PLoS One2019
31594549Extensive transcriptomic study emphasizes importance of vesicular transport in C9orf72 expansion carriers.Acta Neuropathol Commun2019
30739198Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.Acta Neuropathol2019
31104630Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight.Genome Biol2019
30815899Host genetic variation in tumor necrosis factor and nuclear factor-κB pathways and overall survival in mantle cell lymphoma: A discovery and replication study.Am J Hematol2019
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Collaborators

Xue Wang
Mayo Clinic
Co-authored papers 26
Nil??fer Ertekin-Taner
Mayo Clinic
Co-authored papers 24
Dennis W Dickson
Mayo Clinic Jacksonville
Co-authored papers 24
Neill R Graff-Radford
Mayo Clinic Florida
Co-authored papers 19
Steven G Younkin
Mayo Clinic
Co-authored papers 17
Minerva M Carrasquillo
Mayo Clinic
Co-authored papers 16
Daniel J Serie
Mayo Clinic
Co-authored papers 14
Jean-Pierre A Kocher
Mayo Clinic
Co-authored papers 14
Mariet Allen
Mayo Clinic
Co-authored papers 13
Rosa Rademakers
University of Antwerp
Co-authored papers 13
Krishna S Nair
Co-authored papers 12
Ronald C Petersen
Mayo Clinic Rochester
Co-authored papers 12
Thuy Nguyen
Mayo Clinic
Co-authored papers 11
Chen Wang
Center for Individualized Medicine, Mayo Clinic
Co-authored papers 10
Julia E Crook
Center for Clinical and Translational Science, Mayo Clinic
Co-authored papers 9
Kimberly G Malphrus
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Joseph S Reddy
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High Seng Chai
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Ann L Oberg
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Sarah J Lincoln
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Co-authored papers 8
Jeremy D Burgess
Mayo Clinic
Co-authored papers 7
Bradley F Boeve
Mayo Clinic Rochester
Co-authored papers 7
Curtis S Younkin
Mayo Clinic
Co-authored papers 7
Peter Leif Bergsagel
Co-authored papers 7
Rafael Fonseca
Co-authored papers 6
Alexander Keith Stewart
Co-authored papers 6
Todd E Golde
Emory Center for Neurodegenerative Disease
Co-authored papers 6
David S Knopman
Mayo Clinic Rochester
Co-authored papers 6
Nathan D Price
Institute for Systems Biology
Co-authored papers 6
Leonard Petrucelli
Co-authored papers 6
Release 1.2