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Author Details

David J Meyers
Johns Hopkins School of Medicine
2008
38
24
Prashant Mali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37514020Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations.Pharmaceutics2023
35215828The Synthesis and Anti-Cytomegalovirus Activity of Piperidine-4-Carboxamides.Viruses2022
32191456Validation and Characterization of Five Distinct Novel Inhibitors of Human Cytomegalovirus.J Med Chem2020
31939678Signature Fragment Ions of Biotinylated Peptides.J Am Soc Mass Spectrom2020
30910803MITF Expression Predicts Therapeutic Vulnerability to p300 Inhibition in Human Melanoma.Cancer Res2019
30926773Semi-solid prodrug nanoparticles for long-acting delivery of water-soluble antiretroviral drugs within combination HIV therapies.Nat Commun2019
30924641Combination Targeting of the Bromodomain and Acetyltransferase Active Site of p300/CBP.Biochemistry2019
31093674Optimal kinetic exposures for classic and candidate antitrypanosomals.J Antimicrob Chemother2019
29564402Novel Antifungal Compounds Discovered in Medicines for Malaria Venture's Malaria Box.mSphere2018
29056321CBP Regulates Recruitment and Release of Promoter-Proximal RNA Polymerase II.Mol Cell2017
28455448Molecular impact of covalent modifications on nonribosomal peptide synthetase carrier protein communication.J Biol Chem2017
27064363Histone deacetylase inhibitors decrease NHEJ both by acetylation of repair factors and trapping of PARP1 at DNA double-strand breaks in chromatin.Leuk Res2016
27625704Erratum to: CBP binding outside of promoters and enhancers in Drosophila melanogaster.Epigenetics Chromatin2016
25605895Pharmacological activation of myosin II paralogs to correct cell mechanics defects.Proc Natl Acad Sci U S A2015
26604986CBP binding outside of promoters and enhancers in Drosophila melanogaster.Epigenetics Chromatin2015
26124156Resistance to the antimicrobial agent fosmidomycin and an FR900098 prodrug through mutations in the deoxyxylulose phosphate reductoisomerase gene (dxr).Antimicrob Agents Chemother2015
24247136Antimalarial efficacy of hydroxyethylapoquinine (SN-119) and its derivatives.Antimicrob Agents Chemother2014
24379407Control of Foxo1 gene expression by co-activator P300.J Biol Chem2014
23698071Selective inhibition of p300 HAT blocks cell cycle progression, induces cellular senescence, and inhibits the DNA damage response in melanoma cells.J Invest Dermatol2013
23634668Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells.J Med Chem2013
22459148MicroRNA-224 is up-regulated in hepatocellular carcinoma through epigenetic mechanisms.FASEB J2012
25382872Regulation of <i>Myf5</i> Early Enhancer by Histone Acetyltransferase p300 during Stem Cell Differentiation.Mol Biol2012
22961914Live-cell studies of p300/CBP histone acetyltransferase activity and inhibition.Chembiochem2012
22933779p300/CBP-associated factor selectively regulates the extinction of conditioned fear.J Neurosci2012
22446836Rapid and orthogonal logic gating with a gibberellin-induced dimerization system.Nat Chem Biol2012
21358638The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.Nat Immunol2011
22015718PI3K/mTOR signaling regulates prostatic branching morphogenesis.Dev Biol2011
21596989Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas.Science2011
21593332Paradoxical enhancement of fear extinction memory and synaptic plasticity by inhibition of the histone acetyltransferase p300.J Neurosci2011
21709130Inhibition of the acetyltransferases p300 and CBP reveals a targetable function for p300 in the survival and invasion pathways of prostate cancer cell lines.Mol Cancer Ther2011
20201064Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes.Stem Cells2010
21036679A highly sensitive ultra performance liquid chromatography-tandem mass spectrometric (UPLC-MS/MS) technique for quantitation of protein free and bound efavirenz (EFV) in human seminal and blood plasma.J Chromatogr B Analyt Technol Biomed Life Sci2010
20869593Acetylation of tau inhibits its degradation and contributes to tauopathy.Neuron2010
20534345Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor.Chem Biol2010
20676058Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains.EMBO J2010
19589780Phosphatidylinositol 3-kinase/Akt pathway targets acetylation of Smad3 through Smad3/CREB-binding protein interaction: contribution to transforming growth factor beta1-induced Epstein-Barr virus reactivation.J Biol Chem2009
18849969A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange.Nature2008
18819080Thin-layer chromatography.Curr Protoc Nucleic Acid Chem2008
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Collaborators

Philip A Cole
Brigham and Women's Hospital, Blavatnik Institute, Harvard Medical School
Co-authored papers 19
Chandrani Mukherjee
Co-authored papers 8
Allison M Churcher
Umea University
Co-authored papers 2
Yungui Zhou
Gladstone Institutes
Co-authored papers 1
Jin Zhang
Co-authored papers 1
Marc Ferrer
National Institutes of Health, National Center for Advancing Translational Sciences
Co-authored papers 1
Li Gan
Helen and Robert Appel Alzheimer's Disease Research Institute
Co-authored papers 1
Wayne Yu
Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University
Co-authored papers 1
Vahram Haroutunian
Co-authored papers 1
David M Berman
Queen's University
Co-authored papers 1
Prashant Mali (CM4AI)
University of California San Diego
Co-authored papers 1
Robert A Brodsky
Sidney Kimmel Cancer Center, Johns Hopkins University
Co-authored papers 1
Linzhao Cheng
Johns Hopkins University School of Medicine
Co-authored papers 1
Eliezer Masliah
National Institute On Aging
Co-authored papers 1
William W Seeley
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 1
Noel Southall
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 1
Jef D Boeke
Institute for Systems Genetics, NYU School of Medicine
Co-authored papers 1
Feyruz V Rassool
University of Maryland Greenebaum Comprehensive Cancer Center
Co-authored papers 1
Eric J Huang
University of California san francisco
Co-authored papers 1
Mitzi I Kuroda
Co-authored papers 1
Allan Bradley
The Wellcome Trust Sanger Institute
Co-authored papers 1
Brian W Simons
Center for Comparative Medicine, Baylor College of Medicine
Co-authored papers 1
Michael S Kobor
University of British Columbia
Co-authored papers 1
Mingxuan Wu
Co-authored papers 1
John R Yates
TheScripps Research Institute
Co-authored papers 1
Akhilesh Pandey
Co-authored papers 1
Bin-Kuan Chou
The Institute for Cell Engineering, Johns Hopkins University
Co-authored papers 1
Ronen Marmorstein
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 1
Tamara L Lotan
Johns Hopkins University School of Medicine
Co-authored papers 1
Jizhong Zou
and Blood Institute, National Institutes of Health
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Release 1.2