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Author Details

Terrance G Johns
Telethon Kids Institute
1990
112
46
PMIDPaper TitleJournal TitlePublished Year
37333134Preventing recurrence in Sonic Hedgehog Subgroup Medulloblastoma using the OLIG2 inhibitor CT-179.Res Sq2023
36976462Clinical Trials in the Brain Tumour Population: Challenges and Strategies for the Future.Curr Oncol Rep2023
37467718A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence.Cell Rep Med2023
36119496ErbB4 in the brain: Focus on high grade glioma.Front Oncol2022
36497413Anoctamins and Calcium Signalling: An Obstacle to EGFR Targeted Therapy in Glioblastoma?Cancers (Basel)2022
36230692Potassium Ion Channels in Malignant Central Nervous System Cancers.Cancers (Basel)2022
33472956Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastoma.Sci Transl Med2021
37185327LUMOS - Low and Intermediate Grade Glioma Umbrella Study of Molecular Guided TherapieS at relapse: Protocol for a pilot study.BMJ Open2021
33863878Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells.Cell Death Discov2021
31504812Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophore.Neuro Oncol2020
31965010Publisher Correction: A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.Sci Rep2020
31973233Q-Cell Glioblastoma Resource: Proteomics Analysis Reveals Unique Cell-States are Maintained in 3D Culture.Cells2020
32804161A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies.J Vis Exp2020
32168910MK2 Inhibition Induces p53-Dependent Senescence in Glioblastoma Cells.Cancers (Basel)2020
31002307Most clinical anti-EGFR antibodies do not neutralize both wtEGFR and EGFRvIII activation in glioma.Neuro Oncol2019
32259073Lower Tubulin Expression in Glioblastoma Stem Cells Attenuates Efficacy of Microtubule-Targeting Agents.ACS Pharmacol Transl Sci2019
31582283Whole genome and biomarker analysis of patients with recurrent glioblastoma on bevacizumab: A subset analysis of the CABARET trial.J Clin Neurosci2019
31463571The dystroglycan receptor maintains glioma stem cells in the vascular niche.Acta Neuropathol2019
30894629A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.Sci Rep2019
29718345PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein.Neuro Oncol2018
29944980Changes in cell morphology guide identification of tubulin as the off-target for protein kinase inhibitors.Pharmacol Res2018
29941341Gefitinib and Methotrexate to Treat Ectopic Pregnancies with a Pre-Treatment Serum hCG 1000-10,000⿯IU/L: Phase II Open Label, Single Arm Multi-Centre Trial.EBioMedicine2018
30044378Activation of ERBB4 in Glioblastoma Can Contribute to Increased Tumorigenicity and Influence Therapeutic Response.Cancers (Basel)2018
29933129Differential Sensitivity of Human Hepatocellular Carcinoma Xenografts to an IGF-II Neutralizing Antibody May Involve Activated STAT3.Transl Oncol2018
29574250A Pre-Clinical Assessment of the Pan-ERBB Inhibitor Dacomitinib in Pediatric and Adult Brain Tumors.Neoplasia2018
28690875Combination of palbociclib and radiotherapy for glioblastoma.Cell Death Discov2017
28435525Development and Biological Evaluation of a Photoactivatable Small Molecule Microtubule-Targeting Agent.ACS Med Chem Lett2017
28501939Dianthin-30 or gelonin versus monomethyl auristatin E, each configured with an anti-calcitonin receptor antibody, are differentially potent in vitro in high-grade glioma cell lines derived from glioblastoma.Cancer Immunol Immunother2017
28206758Structural Optimization and Pharmacological Evaluation of Inhibitors Targeting Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases (DYRK) and CDC-like kinases (CLK) in Glioblastoma.J Med Chem2017
28504693Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma.Oncogenesis2017
26750997Incomplete target neutralization by the anti-cancer antibody rilotumumab.MAbs2016
27822137Axitinib Has Antiangiogenic and Antitumorigenic Activity in Myxoid Liposarcoma.Sarcoma2016
27551537EGFRvIII: the promiscuous mutation.Cell Death Discov2016
27551510Mitochondrial DNA plasticity is an essential inducer of tumorigenesis.Cell Death Discov2016
24747966Glioma-specific Domain IV EGFR cysteine mutations promote ligand-induced covalent receptor dimerization and display enhanced sensitivity to dacomitinib in vivo.Oncogene2015
26556723Targeted drug delivery using genetically engineered diatom biosilica.Nat Commun2015
26416849Placental-Specific sFLT-1 e15a Protein Is Increased in Preeclampsia, Antagonizes Vascular Endothelial Growth Factor Signaling, and Has Antiangiogenic Activity.Hypertension2015
26519552Pharmacology of novel small-molecule tubulin inhibitors in glioblastoma cells with enhanced EGFR signalling.Biochem Pharmacol2015
27551460Cytotoxic activity of the MK2 inhibitor CMPD1 in glioblastoma cells is independent of MK2.Cell Death Discov2015
25659577EGFRvIII-mediated transactivation of receptor tyrosine kinases in glioma: mechanism and therapeutic implications.Oncogene2015
25719248Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny.Cell Death Dis2015
25806119Neurosphere and adherent culture conditions are equivalent for malignant glioma stem cell lines.Anat Cell Biol2015
25795597DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications.Pharmacol Ther2015
24068568The tumor suppressor microRNA, miR-124a, is regulated by epigenetic silencing and by the transcriptional factor, REST in glioblastoma.Tumour Biol2014
24995151Quantitative intratumoural microdistribution and kinetics of (131)I-huA33 antibody in patients with colorectal carcinoma.EJNMMI Res2014
24812320Combination gefitinib and methotrexate treatment for non-tubal ectopic pregnancies: a case series.Hum Reprod2014
24383468The identification of mitochondrial DNA variants in glioblastoma multiforme.Acta Neuropathol Commun2014
23288908Targeted nanoparticle delivery of doxorubicin into placental tissues to treat ectopic pregnancies.Endocrinology2013
24084530Combination gefitinib and methotrexate compared with methotrexate alone to treat ectopic pregnancy.Obstet Gynecol2013
24084529Effects of gefitinib, an epidermal growth factor receptor inhibitor, on human placental cell growth.Obstet Gynecol2013
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Collaborators

Co-authored papers 21
Co-authored papers 16
University of Melbourne
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Ludwig Institute for Cancer Research
Co-authored papers 13
Monash University
Co-authored papers 10
Ludwig Institute for Cancer Research, University of California San Diego
Co-authored papers 10
Olivia Newton-John Cancer Research Institute
Co-authored papers 7
University of California San Diego
Co-authored papers 6
Perth Children's Hospital
Co-authored papers 4
National Institutes of Health
Co-authored papers 3
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Stanford University
Co-authored papers 3
Regeneron Pharmaceuticals Inc.
Co-authored papers 3
Genentech Inc.
Co-authored papers 2
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Olivia Newton-John Cancer Research Institute
Co-authored papers 2
St. Jude Children's Research Hospital
Co-authored papers 1
Co-authored papers 1
Division of Pharmaceutical Sciences, Duquesne University School of Pharmacy
Co-authored papers 1
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 1
Peter MacCallum Cancer Centre
Co-authored papers 1
QIMR Berghofer Medical Research Institute
Co-authored papers 1
Yale School of Medicine
Co-authored papers 1
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
VIB-Center for Cancer Biology
Co-authored papers 1
Northwestern University Feinberg School of Medicine
Co-authored papers 1
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 1
UPMC Hillman Cancer Center, University of Pittsburgh Medical Center
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University of California san francisco
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Harvard Medical School
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