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Author Details

David F Savage
University of California berkeley
2003
57
32
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38085650α-Carboxysome Size Is Controlled by the Disordered Scaffold Protein CsoS2.Biochemistry2024
37127263Rubisco Function, Evolution, and Engineering.Annu Rev Biochem2023
37155899Carbon isotope fractionation by an ancestral rubisco suggests that biological proxies for CO<sub>2</sub> through geologic time should be reevaluated.Proc Natl Acad Sci U S A2023
37403358Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs.Mol Ther2023
36282790Exploring Masses and Internal Mass Distributions of Single Carboxysomes in Free Solution Using Fluorescence and Interferometric Scattering in an Anti-Brownian Trap.J Phys Chem B2022
35549289Ratiometric Sensing of Redox Environments Inside Individual Carboxysomes Trapped in Solution.J Phys Chem Lett2022
35730550Workshop-based learning and networking: a scalable model for research capacity strengthening in low- and middle-income countries.Glob Health Action2022
36423580Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors.Cell2022
36454757Trajectories for the evolution of bacterial CO<sub>2</sub>-concentrating mechanisms.Proc Natl Acad Sci U S A2022
35982043Rubisco forms a lattice inside alpha-carboxysomes.Nat Commun2022
34751132A nanocompartment system contributes to defense against oxidative stress in <i>Mycobacterium tuberculosis</i>.Elife2021
33798818New discoveries expand possibilities for carboxysome engineering.Curr Opin Microbiol2021
34815415The encapsulin from Thermotoga maritima is a flavoprotein with a symmetry matched ferritin-like cargo protein.Sci Rep2021
34580310Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules.Nat Commun2021
32123388Multivalent interactions between CsoS2 and Rubisco mediate α-carboxysome formation.Nat Struct Mol Biol2020
33084575Functional reconstitution of a bacterial CO<sub>2</sub> concentrating mechanism in <i>Escherichia coli</i>.Elife2020
32645407Recent advances on the structure and function of NDH-1: The complex I of oxygenic photosynthesis.Biochim Biophys Acta Bioenerg2020
30633905CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification.Cell2019
31182863Author Correction: Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors.Nat Biotechnol2019
31406332DABs are inorganic carbon pumps found throughout prokaryotic phyla.Nat Microbiol2019
31259528Revisiting Trade-offs between Rubisco Kinetic Parameters.Biochemistry2019
31073154Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs.Nat Commun2019
30742075Structure of the complex I-like molecule NDH of oxygenic photosynthesis.Nature2019
30740978Cas14: Big Advances from Small CRISPR Proteins.Biochemistry2019
30968695Learning to Build a β-Carboxysome.Biochemistry2019
31110355Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors.Nat Biotechnol2019
31082222Multiplexed Charge Detection Mass Spectrometry for High-Throughput Single Ion Analysis of Large Molecules.Anal Chem2019
30527541A Hard Day's Night: Cyanobacteria in Diel Cycles.Trends Microbiol2019
28992412Protein Science by DNA Sequencing: How Advances in Molecular Biology Are Accelerating Biochemistry.Biochemistry2018
28635326Encapsulins: molecular biology of the shell.Crit Rev Biochem Mol Biol2017
28707884Rapid and Programmable Protein Mutagenesis Using Plasmid Recombineering.ACS Synth Biol2017
27486247The stringent response regulates adaptation to darkness in the cyanobacterium Synechococcus elongatus.Proc Natl Acad Sci U S A2016
26608811Programmed Ribosomal Frameshifting Mediates Expression of the α-Carboxysome.J Mol Biol2016
27768949Biofuel metabolic engineering with biosensors.Curr Opin Chem Biol2016
27978999Editorial Overview. Biofuels: At the crossroads.Curr Opin Chem Biol2016
27805047An open-hardware platform for optogenetics and photobiology.Sci Rep2016
27470466Rapid construction of metabolite biosensors using domain-insertion profiling.Nat Commun2016
27551079pH determines the energetic efficiency of the cyanobacterial CO2 concentrating mechanism.Proc Natl Acad Sci U S A2016
27224728Identification of a Minimal Peptide Tag for in Vivo and in Vitro Loading of Encapsulin.Biochemistry2016
27136077Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch.Nat Biotechnol2016
25366827Live-cell imaging of cyanobacteria.Photosynth Res2015
25398355Protein engineering of Cas9 for enhanced function.Methods Enzymol2014
24023971The bacterial carbon-fixing organelle is formed by shell envelopment of preassembled cargo.PLoS One2013
22184212Modularity of a carbon-fixing protein organelle.Proc Natl Acad Sci U S A2012
23112856Spatial and temporal organization of chromosome duplication and segregation in the cyanobacterium Synechococcus elongatus PCC 7942.PLoS One2012
20363793Engineering cyanobacteria to synthesize and export hydrophilic products.Appl Environ Microbiol2010
20855585Structural context shapes the aquaporin selectivity filter.Proc Natl Acad Sci U S A2010
20203050Spatially ordered dynamics of the bacterial carbon fixation machinery.Science2010
19360018A general protocol for the crystallization of membrane proteins for X-ray structural investigation.Nat Protoc2009
18205286Defossiling fuel: how synthetic biology can transform biofuel production.ACS Chem Biol2008
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Collaborators

Robert M Stroud
University of California San Francisco
Co-authored papers 9
Pamela A Silver
Harvard Medical School
Co-authored papers 6
Jennifer A Doudna
Innovative Genomics Institute, University of California berkeley
Co-authored papers 6
Robert J Nichols
Stanford University
Co-authored papers 5
Larry J W Miercke
University of California San Francisco
Co-authored papers 5
Joseph D O'Connell
Department of Pharmaceutical Chemistry, University of California-San Francisco
Co-authored papers 4
William Harries
University of California san francisco
Co-authored papers 3
David R Liu
Co-authored papers 2
Evan R Williams
University of California berkeley
Co-authored papers 2
Oren S Rosenberg
University of California san francisco
Co-authored papers 2
Katie A Lien
Pritzker School of Medicine, University of Chicago
Co-authored papers 2
Robert Nichols
University of California berkeley
Co-authored papers 1
Michael Rape
Howard Hughes Medical Institute, University of California at Berkeley
Co-authored papers 1
Joseph D Ho
University of California san francisco
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Lucy M Li
Co-authored papers 1
Adam P Arkin
Lawrence Berkeley National Laboratory
Co-authored papers 1
Jennifer K Sabo
Innovative Genomics Institute, University of California berkeley
Co-authored papers 1
Ivan Mwebaza
Case Western Reserve University School of Medicine
Co-authored papers 1
Stephen L Isaacs
Robert Wood Johnson Foundation in Princeton
Co-authored papers 1
Manu Vanaerschot
Columbia University Irving Medical Center
Co-authored papers 1
Janet Finer-Moore
University of California San Francisco
Co-authored papers 1
Patrick M Shih
Co-authored papers 1
Eric Lee
School of Public Health, University of California berkeley
Co-authored papers 1
Nadine Czudnochowski
University of California san francisco
Co-authored papers 1
Peter Walter
University of California san francisco
Co-authored papers 1
Matt Knight
University of California berkeley
Co-authored papers 1
Isabelle Charles
Co-authored papers 1
Arthur Reingold
University of California berkeley
Co-authored papers 1
David P Kateete
College of Health Sciences, Makerere University
Co-authored papers 1
Release 1.2