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Author Details

Brenda J Andrews
University of Toronto
1983
221
73
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36909656PIFiA: Self-supervised Approach for Protein Functional Annotation from Single-Cell Imaging Data.bioRxiv2023
37556359Highlighting rare disease research with a GENETICS and G3 series on genetic models of rare diseases.G3 (Bethesda)2023
37556311Highlighting rare disease research with a GENETICS and G3 series on genetic models of rare diseases.Genetics2023
37891180N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity.Nat Commun2023
38045359Single-cell imaging of protein dynamics of paralogs reveals mechanisms of gene retention.bioRxiv2023
37205480K29-linked unanchored polyubiquitin chains disrupt ribosome biogenesis and direct ribosomal proteins to the Intranuclear Quality control compartment (INQ).bioRxiv2023
37201508Reproducibility metrics for context-specific CRISPR screens.Cell Syst2023
35087094High-throughput platform for yeast morphological profiling predicts the targets of bioactive compounds.NPJ Syst Biol Appl2022
36037231Repression of essential cell cycle genes increases cellular fitness.PLoS Genet2022
35896733Imaging cell biology.Nat Cell Biol2022
35285506Phenomics approaches to understand genetic networks and gene function in yeast.Biochem Soc Trans2022
33462440Ï¿-SGA: synthetic genetic array analysis for systematically screening and quantifying trigenic interactions in yeast.Nat Protoc2021
33853860Setting molecular traps in yeast for identification of anticancer drug targets.Proc Natl Acad Sci U S A2021
33733368Trigenic Synthetic Genetic Array (Ï¿-SGA) Technique for Complex Interaction Analysis.Methods Mol Biol2021
34544148A decade of G3: Genes|Genomes|Genetics: a unified home for genetics and genomics research.G3 (Bethesda)2021
34018332A method for benchmarking genetic screens reveals a predominant mitochondrial bias.Mol Syst Biol2021
34096681A genome-scale yeast library with inducible expression of individual genes.Mol Syst Biol2021
33958448Environmental robustness of the global yeast genetic interaction network.Science2021
34028720High-Throughput Imaging of Arrays of Fluorescently Tagged Yeast Mutant Strains.Methods Mol Biol2021
33974913Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase.Mol Cell2021
34139168Single-cell image analysis to explore cell-to-cell heterogeneity in isogenic populations.Cell Syst2021
32694731Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.Nat Metab2020
32064787Systematic genetics and single-cell imaging reveal widespread morphological pleiotropy and cell-to-cell variability.Mol Syst Biol2020
33081638The structure and function of deubiquitinases: lessons from budding yeast.Open Biol2020
32939983Systematic analysis of bypass suppression of essential genes.Mol Syst Biol2020
32934016TheCellVision.org: A Database for Visualizing and Mining High-Content Cell Imaging Projects.G3 (Bethesda)2020
32586993Exploring whole-genome duplicate gene retention with complex genetic interaction analysis.Science2020
30573466Identifying <i>Pseudomonas syringae</i> Type III Secreted Effector Function via a Yeast Genomic Screen.G3 (Bethesda)2019
30804202Complex modifier landscape underlying genetic background effects.Proc Natl Acad Sci U S A2019
30974317Genetic interaction networks in cancer cells.Curr Opin Genet Dev2019
30901552Global Genetic Networks and the Genotype-to-Phenotype Relationship.Cell2019
29043651Reporter-Based Synthetic Genetic Array Analysis: A Functional Genomics Approach for Investigating Transcript or Protein Abundance Using Fluorescent Proteins in Saccharomyces cerevisiae.Methods Mol Biol2018
29903533Genetic Network Complexity Shapes Background-Dependent Phenotypic Expression.Trends Genet2018
30059827Integrating genetic and protein-protein interaction networks maps a functional wiring diagram of a cell.Curr Opin Microbiol2018
29674565Systematic analysis of complex genetic interactions.Science2018
29620521Integrating images from multiple microscopy screens reveals diverse patterns of change in the subcellular localization of proteins.Elife2018
27940887Machine learning and computer vision approaches for phenotypic profiling.J Cell Biol2017
30505984Mapping a diversity of genetic interactions in yeast.Curr Opin Syst Biol2017
28325812TheCellMap.org: A Web-Accessible Database for Visualizing and Mining the Global Yeast Genetic Interaction Network.G3 (Bethesda)2017
28122947Functional Analysis of Kinases and Transcription Factors in <i>Saccharomyces cerevisiae</i> Using an Integrated Overexpression Library.G3 (Bethesda)2017
28420678Automated analysis of high-content microscopy data with deep learning.Mol Syst Biol2017
29161247Errata: Functional annotation of chemical libraries across diverse biological processes.Nat Chem Biol2017
29161244Errata: Functional annotation of chemical libraries across diverse biological processes.Nat Chem Biol2017
28542158Identifying pathogenicity of human variants via paralog-based yeast complementation.PLoS Genet2017
28582599Mechanisms of suppression: The wiring of genetic resilience.Bioessays2017
28894103The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation.Nat Commun2017
28655737Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens.G3 (Bethesda)2017
28839119Taxonomically Restricted Genes with Essential Functions Frequently Play Roles in Chromosome Segregation in <i>Caenorhabditis elegans</i> and <i>Saccharomyces cerevisiae</i>.G3 (Bethesda)2017
28759014Functional annotation of chemical libraries across diverse biological processes.Nat Chem Biol2017
26871637Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.Cell2016
  • 1 - 50 of 221

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Collaborators

Charles Boone
University of Toronto
Co-authored papers 108
Michael Costanzo
Co-authored papers 55
Chad L Myers
University of Minnesota - Twin Cities
Co-authored papers 39
Helena Friesen
University of Toronto
Co-authored papers 27
Jason Moffat
University of Toronto
Co-authored papers 21
Zhijian Li
University of Toronto
Co-authored papers 13
Grant W Brown
University of Toronto, 1 King's College Circle
Co-authored papers 13
Amy Hin Yan Tong
University of Toronto
Co-authored papers 12
Frederick P Roth
University of Toronto
Co-authored papers 11
Franco J Vizeacoumar
College of Medicine, University of Saskatchewan
Co-authored papers 9
Gary D Bader
University of Toronto
Co-authored papers 9
Mike Tyers
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
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Carles Pons
Co-authored papers 8
Huiming Ding
Massachusetts Institute of Technology
Co-authored papers 8
Gordon Chua
University of Calgary
Co-authored papers 8
Anne-Claude Gingras
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 8
Timothy R Hughes
University of Toronto
Co-authored papers 7
Howard Bussey
McGill University
Co-authored papers 7
Philip Hieter
University of British Columbia
Co-authored papers 7
Jack F Greenblatt
College Street, University of Toronto
Co-authored papers 7
Jennifer Haynes
Joan C. Edwards School of Medicine, Marshall University
Co-authored papers 6
Yuen Ho
University of Toronto
Co-authored papers 6
Yiqun Chen
University of Toronto, College Street
Co-authored papers 6
Sondra Bahr
University of Toronto, College Street
Co-authored papers 6
Justin Nelson
Co-authored papers 5
Kristin Baetz
Ottawa Institute of Systems Biology, University of Ottawa, University of Calgary
Co-authored papers 5
Patrick Aloy
Institucio Catalana de Recerca i Estudis Avancats (ICREA)
Co-authored papers 5
Frederick S Vizeacoumar
College of Medicine, University of Saskatchewan
Co-authored papers 5
Hongwei Zhu
Peking Union Medical College Hospital
Co-authored papers 5
Quaid Morris
Sloan Kettering Institute
Co-authored papers 5
Release 1.2