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Author Details

Paul P Tak
1992
577
108
PMIDPaper TitleJournal TitlePublished Year
37228396Uncovering transcriptomic landscape alterations of CAN-2409 in <i>in vitro</i> and <i>in vivo</i> glioma models.Front Med (Lausanne)2023
36768186Mammalian Glycosylation Patterns Protect Citrullinated Chemokine MCP-1/CCL2 from Partial Degradation.2023
35017150Systemic high-dose dexamethasone treatment may modulate the efficacy of intratumoral viral oncolytic immunotherapy in glioblastoma models.J Immunother Cancer2022
36032633Perturbing DDR signaling enhances cytotoxic effects of local oncolytic virotherapy and modulates the immune environment in glioma.Mol Ther Oncolytics2022
35406668Increased Frequency of CD4 Follicular Helper T and CD8 Follicular T Cells in Human Lymph Node Biopsies during the Earliest Stages of Rheumatoid Arthritis.Cells2022
36477362A randomized, phase II study of sequential belimumab and rituximab in primary Sjögren's syndrome.2022
34902228Toward Individualized Prediction of Response to Methotrexate in Early Rheumatoid Arthritis: A Pharmacogenomics-Driven Machine Learning Approach.Arthritis Care Res (Hoboken)2022
35203534Impact of Adalimumab Treatment on Interleukin-17 and Interleukin-17 Receptor Expression in Skin and Synovium of Psoriatic Arthritis Patients with Mild Psoriasis.Biomedicines2022
34389633A randomised, placebo-controlled study of RIPK1 inhibitor GSK2982772 in patients with active ulcerative colitis.BMJ Open Gastroenterology2021
33968050Novel Insights Into Rheumatoid Arthritis Through Characterization of Concordant Changes in DNA Methylation and Gene Expression in Synovial Biopsies of Patients With Differing Numbers of Swollen Joints.Front Immunol2021
33726834A randomized, placebo-controlled experimental medicine study of RIPK1 inhibitor GSK2982772 in patients with moderate to severe rheumatoid arthritis.2021
34675389Immune-mediated inflammation across disease boundaries: breaking down research silos.Nature Immunology2021
31377797Promotion of macrophage activation by Tie2 in the context of the inflamed synovia of rheumatoid arthritis and psoriatic arthritis patients.Rheumatology2020
32094157Is treat-to-target really working in rheumatoid arthritis? a longitudinal analysis of a cohort of patients treated in daily practice (RA BIODAM).Annals of the Rheumatic Diseases2020
33015599cDC1 are required for the initiation of collagen-induced arthritis.Journal of Translational Autoimmunity2020
32784936Human Lymph Node Stromal Cells Have the Machinery to Regulate Peripheral Tolerance during Health and Rheumatoid Arthritis.International Journal of Molecular Sciences2020
31474600Outcomes and Findings of the International Rheumatoid Arthritis (RA) BIODAM Cohort for Validation of Soluble Biomarkers in RA.Journal of Rheumatology2020
31330824Myeloid Dendritic Cells Are Enriched in Lymph Node Tissue of Early Rheumatoid Arthritis Patients but not in At Risk Individuals.Cells2019
30504445Effects of B-cell directed therapy on the preclinical stage of rheumatoid arthritis: the PRAIRI study.Annals of the Rheumatic Diseases2019
30420245Incidence and risk factors for adalimumab and infliximab anti-drug antibodies in rheumatoid arthritis: A European retrospective multicohort analysis.Semin Arthritis Rheum2019
30649469Effect of rituximab treatment on T and B cell subsets in lymph node biopsies of patients with rheumatoid arthritis.Rheumatology2019
31481955Molecular Characterization of Human Lymph Node Stromal Cells During the Earliest Phases of Rheumatoid Arthritis.Frontiers in Immunology2019
31217169Non-response to rituximab therapy in rheumatoid arthritis is associated with incomplete disruption of the B cell receptor repertoire.Annals of the Rheumatic Diseases2019
31068673Therapeutic options for targeting inflammatory osteoarthritis pain.Nature reviews. Rheumatology2019
30898822Phase III, multicentre, randomised, double-blind, placebo-controlled, 104-week study of subcutaneous belimumab administered in combination with rituximab in adults with systemic lupus erythematosus (SLE): BLISS-BELIEVE study protocol.BMJ Open2019
29795407Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients.Pharmacogenomics J2018
28389989Single vagus nerve stimulation reduces early postprandial C-peptide levels but not other hormones or postprandial metabolism.Clinical Rheumatology2018
30155621Fibroblasts and Osteoblasts in Inflammation and Bone Damage.Advances in Experimental Medicine and Biology2018
30092827Induction of sustained remission in early inflammatory arthritis with the combination of infliximab plus methotrexate: the DINORA trial.2018
29907666Physician's Global Assessment in Psoriatic Arthritis: A Multicenter GRAPPA Study.J Rheumatol2018
29483080Efficacy and safety of monotherapy with sirukumab compared with adalimumab monotherapy in biologic-naïve patients with active rheumatoid arthritis (SIRROUND-H): a randomised, double-blind, parallel-group, multinational, 52-week, phase 3 study.Annals of the Rheumatic Diseases2018
29482663Impaired lymph node stromal cell function during the earliest phases of rheumatoid arthritis.Arthritis Res Ther2018
29379035Distinctive expression of T cell guiding molecules in human autoimmune lymph node stromal cells upon TLR3 triggering.Sci Rep2018
29471421Class 3 semaphorins modulate the invasive capacity of rheumatoid arthritis fibroblast-like synoviocytes.Rheumatology2018
29587639MiR-146a G/C rs2910164 variation in South African Indian and Caucasian patients with psoriatic arthritis.BMC Medical Genetics2018
28128853Protein arginine deiminase 4 inhibition is sufficient for the amelioration of collagen-induced arthritis.Clin Exp Immunol2017
28690611Insight into the Endocrine System and the Immune System: A Review of the Inflammatory Role of Prolactin in Rheumatoid Arthritis and Psoriatic Arthritis.Frontiers in Immunology2017
28688467Prediction of Response to Targeted Treatment in Rheumatoid Arthritis.Mayo Clinic Proceedings2017
28642278Rheumatoid arthritis and psoriatic arthritis synovial fluids stimulate prolactin production by macrophages.Journal of Leukocyte Biology2017
28855173Sirukumab for rheumatoid arthritis: the phase III SIRROUND-D study.Annals of the Rheumatic Diseases2017
28547815Balancing the autonomic nervous system to reduce inflammation in rheumatoid arthritis.Journal of Internal Medicine2017
28935945Synovial tissue research: a state-of-the-art review.Nature reviews. Rheumatology2017
28793332Stromal cell markers are differentially expressed in the synovial tissue of patients with early arthritis.PLoS ONE2017
28790026Dominant B cell receptor clones in peripheral blood predict onset of arthritis in individuals at risk for rheumatoid arthritis.Annals of the Rheumatic Diseases2017
28701760Synovial tissue research: a state-of-the-art review.Nature reviews. Rheumatology2017
28321219Computational Model Reveals Limited Correlation between Germinal Center B-Cell Subclone Abundancy and Affinity: Implications for Repertoire Sequencing.Frontiers in Immunology2017
29255214Corrigendum: Synovial tissue research: a state-of-the-art review.Nature reviews. Rheumatology2017
27428460Brief Report: Altered Innate Lymphoid Cell Subsets in Human Lymph Node Biopsy Specimens Obtained During the At-Risk and Earliest Phases of Rheumatoid Arthritis.Arthritis Rheumatol2017
27457515Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes.Annals of the Rheumatic Diseases2017
27807638Hormone, metabolic peptide, and nutrient levels in the earliest phases of rheumatoid arthritis-contribution of free fatty acids to an increased cardiovascular risk during very early disease.Clinical Rheumatology2017
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Brigham and Women's Hospital and Harvard Medical School
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Brigham and Women's Hospital
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Hospital for Special Surgery and Weill Cornell Medical College
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Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital
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