Author details

Full Name

Jae K Lee

Affiliation

ORCID

Career Start Year

1999

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
31418636	Treatment of Uveitis and Outcomes of Glaucoma Drainage Implant Surgery: A Meta-Analysis.	Ocular Immunology and Inflammation	2020
30240435	Biologically anchored knowledge expansion approach uncovers KLF4 as a novel insulin signaling regulator.	PLoS ONE	2018
30403750	Correction: Biologically anchored knowledge expansion approach uncovers KLF4 as a novel insulin signaling regulator.	PLoS ONE	2018
28197408	Module Anchored Network Inference: A Sequential Module-Based Approach to Novel Gene Network Construction from Genomic Expression Data on Human Disease Mechanism.	International Journal of Genomics	2017
23839122	Point success rate for patient therapeutic response prediction by continuous biomarker scores.	Statistical Methods in Medical Research	2016
26332118	Transcription profiling of CD4âº T cells in rhesus macaques that infected with simian-human immunodeficiency virus and re-challenged with SIVmac251.	Journal of Medical Primatology	2015
25180633	A thirteen-gene expression signature predicts survival of patients with pancreatic cancer and identifies new genes of interest.	PLoS One	2014
25347450	Circulating fibrocytes as biomarker of prognosis in Hermansky-Pudlak syndrome.	Am J Respir Crit Care Med	2014
24302644	Effects of stretch and shortening on gene expression in intact myocardium.	Physiological Genomics	2014
24505259	Retrospective analysis of survival improvement by molecular biomarker-based personalized chemotherapy for recurrent ovarian cancer.	PLoS ONE	2014
23495241	Circulating microRNA as a biomarker of human growth hormone administration to patients.	Drug Testing and Analysis	2014
24942736	A cleavage-potentiated fragment of tear lacritin is bactericidal.	Journal of Biological Chemistry	2014
23386689	Hepatocyte growth factor sensitizes brain tumors to c-MET kinase inhibition.	Clin Cancer Res	2013
24204737	Clinical, molecular and genetic validation of a murine orthotopic xenograft model of pancreatic adenocarcinoma using fresh human specimens.	PLoS One	2013
23836031	Circulating levels of IL-1B+IL-6 cause ER stress and dysfunction in islets from prediabetic male mice.	Endocrinology	2013
24369834	Calpain 2 activation of P-TEFb drives megakaryocyte morphogenesis and is disrupted by leukemogenic GATA1 mutation.	Dev Cell	2013
23640897	Lacritin rescues stressed epithelia via rapid forkhead box O3 (FOXO3)-associated autophagy that restores metabolism.	Journal of Biological Chemistry	2013
23558954	Diacylglycerol kinase Î± is a critical signaling node and novel therapeutic target in glioblastoma and other cancers.	Cancer Discovery	2013
22201681	Genetic inactivation of IL-1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice.	Journal of Clinical Investigation	2012
22348014	Multi-gene expression predictors of single drug responses to adjuvant chemotherapy in ovarian carcinoma: predicting platinum resistance.	PLoS One	2012
23185353	A systematic evaluation of multi-gene predictors for the pathological response of breast cancer patients to chemotherapy.	PLoS ONE	2012
22244445	Molecular prediction for atherogenic risks across different cell types of leukocytes.	BMC Med Genomics	2012
22034872	Enhanced peptide quantification using spectral count clustering and cluster abundance.	BMC Bioinformatics	2011
21169543	IL-2-controlled expression of multiple T cell trafficking genes and Th2 cytokines in the regulatory T cell-deficient scurfy mice: implication to multiorgan inflammation and control of skin and lung inflammation.	Journal of Immunology	2011
21256081	A 20-gene model for molecular nodal staging of bladder cancer: development and prospective assessment.	Lancet Oncol	2011
21253455	Use of yeast chemigenomics and COXEN informatics in preclinical evaluation of anticancer agents.	Neoplasia	2011
22241958	Cyclophilin B expression is associated with in vitro radioresistance and clinical outcome after radiotherapy.	Neoplasia	2011
21925153	Pilot analysis of the plasma metabolite profiles associated with emphysematous Chronic Obstructive Pulmonary Disease phenotype.	Biochemical and Biophysical Research Communications	2011
21884709	In vitro transcriptomic prediction of hepatotoxicity for early drug discovery.	Journal of Theoretical Biology	2011
20652516	Multi-gene expression-based statistical approaches to predicting patients' clinical outcomes and responses.	Methods in Molecular Biology	2010
20713531	Multigene expression-based predictors for sensitivity to Vorinostat and Velcade in non-small cell lung cancer.	Molecular Cancer Therapeutics	2010
20160033	The COXEN principle: translating signatures of in vitro chemosensitivity into tools for clinical outcome prediction and drug discovery in cancer.	Cancer Research	2010
20068086	Prospective comparison of clinical and genomic multivariate predictors of response to neoadjuvant chemotherapy in breast cancer.	Clin Cancer Res	2010
20058246	ReSASC: a resampling-based algorithm to determine differential protein expression from spectral count data.	Proteomics	2010
18850577	Mitochondrial DNA mutation stimulates prostate cancer growth in bone stromal environment.	Prostate	2009
19634200	Inference of large-scale gene regulatory networks using regression-based network approach.	Journal of Bioinformatics and Computational Biology	2009
19246616	Utilizing the molecular gateway: the path to personalized cancer management.	Clinical Chemistry	2009
19667080	Double error shrinkage method for identifying protein binding sites observed by tiling arrays with limited replication.	Bioinformatics	2009
19229372	Genomancy: predicting tumour response to cancer therapy based on the oracle of genetics.		2009
19843853	Concordant gene expression signatures predict clinical outcomes of cancer patients undergoing systemic therapy.	Cancer Research	2009
19881954	Comparison of global versus epidermal growth factor receptor pathway profiling for prediction of lapatinib sensitivity in bladder cancer.	Neoplasia	2009
18237428	Response projected clustering for direct association with physiological and clinical response data.	BMC Bioinformatics	2008
19047182	Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis.	Cancer Res	2008
19115930	Cellular gene expression profiles in rhesus macaques challenged mucosally with a pathogenic R5 tropic simian human immunodeficiency virus isolate.	Viral Immunology	2008
18670642	Molecular credentialing of rodent bladder carcinogenesis models.	Neoplasia	2008
18194724	Data mining in genomics.	Clinics in Laboratory Medicine	2008
17430969	Error-pooling-based statistical methods for identifying novel temporal replication profiles of human chromosomes observed by DNA tiling arrays.	Nucleic Acids Res	2007
17270045	Boolean networks using the chi-square test for inferring large-scale gene regulatory networks.	BMC Bioinformatics	2007
17308055	Prediction of drug combination chemosensitivity in human bladder cancer.	Molecular Cancer Therapeutics	2007
17244792	Induction of dendritic cell-like phenotype in macrophages during foam cell formation.	Physiological Genomics	2007