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Author Details

Naganari Ohkura
Graduate School of Medicine, Osaka University
1989
93
39
PMIDPaper TitleJournal TitlePublished Year
36529525Mature dendritic cells enriched in regulatory molecules may control regulatory T cells and the prognosis of head and neck cancer.Cancer Sci2023
37559728Identification of the novel FOXP3-dependent T<sub>reg</sub> cell transcription factor MEOX1 by high-dimensional analysis of human CD4<sup>+</sup> T cells.Front Immunol2023
37420296S-531011, a Novel Anti-Human CCR8 Antibody, Induces Potent Antitumor Responses through Depletion of Tumor-Infiltrating CCR8-Expressing Regulatory T Cells.Mol Cancer Ther2023
37230937Increased anti-oxidative action compensates for collagen tissue degeneration in vitiligo dermis.Pigment Cell Melanoma Res2023
35140181CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory.Proc Natl Acad Sci U S A2022
35354899The impact of CCR8+ regulatory T cells on cytotoxic T cell function in human lung cancer.Sci Rep2022
35869073Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymoma.Nat Commun2022
33017003VIRTUS: a pipeline for comprehensive virus analysis from conventional RNA-seq data.Bioinformatics2021
33930308Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells.Immunity2021
33414270Reply to Slominski et al.: UVB irradiation induces proenkephalin<sup>+</sup> regulatory T cells with a wound-healing function.Proc Natl Acad Sci U S A2021
32367041Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases.Cell Res2020
32017635Regulatory T Cells and Human Disease.Annu Rev Immunol2020
31950169Clinical importance of the expression of CD4+CD8+ T cells in renal cell carcinoma.Int Immunol2020
32769209Proenkephalin<sup>+</sup> regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function.Proc Natl Acad Sci U S A2020
32362325Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases.Immunity2020
32277125Tumour grade significantly correlates with total dysfunction of tumour tissue-infiltrating lymphocytes in renal cell carcinoma.Sci Rep2020
32414925Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation.Proc Natl Acad Sci U S A2020
30343293Innate Myeloid Cell Subset-Specific Gene Expression Patterns in the Human Colon are Altered in Crohn's Disease Patients.Digestion2019
31681278Dynamic Imprinting of the Treg Cell-Specific Epigenetic Signature in Developing Thymic Regulatory T Cells.Front Immunol2019
31653719Conversion of antigen-specific effector/memory T cells into Foxp3-expressing T<sub>reg</sub> cells by inhibition of CDK8/19.Sci Immunol2019
31209070Regulatory roles of IL-10-producing human follicular T cells.J Exp Med2019
31130948Functional Roles of the IgM Fc Receptor in the Immune System.Front Immunol2019
30726915Loss of TET proteins in regulatory T cells promotes abnormal proliferation, Foxp3 destabilization and IL-17 expression.Int Immunol2019
31027998Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction.Immunity2019
30485427Regulatory T cells expressing abundant CTLA-4 on the cell surface with a proliferative gene profile are key features of human head and neck cancer.Int J Cancer2019
29158419Ultraviolet B-Induced Maturation of CD11b-Type Langerin<sup>-</sup> Dendritic Cells Controls the Expansion of Foxp3<sup>+</sup> Regulatory T Cells in the Skin.J Immunol2018
27992401Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment.Nat Immunol2017
28415767Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells.Oncotarget2017
28323270Erratum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment.Nat Immunol2017
29044238Addendum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment.Nat Immunol2017
28698369A distinct subpopulation of CD25<sup>-</sup> T-follicular regulatory cells localizes in the germinal centers.Proc Natl Acad Sci U S A2017
28850106FANTOM5 CAGE profiles of human and mouse samples.Sci Data2017
28768723Lamtor1 Is Critically Required for CD4<sup>+</sup> T Cell Proliferation and Regulatory T Cell Suppressive Function.J Immunol2017
27078110Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system.Proc Natl Acad Sci U S A2016
27111280Two FOXP3(+)CD4(+) T cell subpopulations distinctly control the prognosis of colorectal cancers.Nat Med2016
25348287Epigenetic control of thymic Treg-cell development.Eur J Immunol2015
25848068Comment on "cutting edge: epigenetic regulation of Foxp3 defines a stable population of CD4+ regulatory T cells in tumors from mice and humans".J Immunol2015
24706905Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation.Proc Natl Acad Sci U S A2014
25464853Continuous T cell receptor signals maintain a functional regulatory T cell pool.Immunity2014
25549298Treating type-1 diabetes with an epigenetic drug.Elife2014
25324392Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease.Science2014
25348622Homeostasis of thymus-derived Foxp3+ regulatory T cells is controlled by ultraviolet B exposure in the skin.J Immunol2014
24670764A promoter-level mammalian expression atlas.Nature2014
23521883Development and maintenance of regulatory T cells.Immunity2013
23675373Molecular determinants of regulatory T cell development: the essential roles of epigenetic changes.Front Immunol2013
23123060T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development.Immunity2012
22999950Treg cells acquire new directions, cytokines navigate.Immunity2012
21237521FOXP3+ regulatory T cells: control of FOXP3 expression by pharmacological agents.Trends Pharmacol Sci2011
21819486Correlation of mutant menin stability with clinical expression of multiple endocrine neoplasia type 1 and its incomplete forms.Cancer Sci2011
21347344HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.PLoS Pathog2011
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Collaborators

Shimon Sakaguchi
Institute for Frontier Medical Sciences, Kyoto University
Co-authored papers 51
Hiromasa Morikawa
WPI Immunology Frontier Research Center, Osaka University
Co-authored papers 6
Masahide Hamaguchi
Kyoto Prefectural University of Medicine
Co-authored papers 5
Sayaka Nagao-Sato
Ochanomizu University
Co-authored papers 3
Yoshihide Hayashizaki
Center for Integrative Medical Sciences
Co-authored papers 3
Masayoshi Itoh
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Timo Lassmann
Telethon Kids Institute, University of Western Australia
Co-authored papers 3
Piero Carninci
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Alistair R R Forrest
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Hideya Kawaji
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Tony J Kenna
Queensland University of Technology
Co-authored papers 2
Takaaki Sugiyama
Co-authored papers 2
Jun Furusawa
Aichi Cancer Center Hospital
Co-authored papers 2
Guojun Sheng
International Research Center for Medical Sciences (IRCMS), Kumamoto University
Co-authored papers 2
Yosuke Mizuno
Yokohama National University
Co-authored papers 2
Haruhiko Koseki
RIKEN Research Center for Allergy and Immunology
Co-authored papers 2
Stefano Gustincich
Istituto Italiano di Tecnologia
Co-authored papers 2
Yuki I Kawamura
Research Institute, National Center for Global Health and Medicine
Co-authored papers 2
Reto Guler
International Centre for Genetic Engineering and Biotechnology
Co-authored papers 2
Albert S B Edge
Harvard Medical School
Co-authored papers 2
Christophe Simon
RIKEN Yokohama Institute
Co-authored papers 2
Peter Heutink
German Center for Neurodegenerative Diseases (DZNE).
Co-authored papers 2
Ernst J Wolvetang
Australian Institute for Bioengineering and Nanotechnology, University of Queensland
Co-authored papers 2
Suzana Savvi
South African Medical Research Council (SAMRC), University of Cape Town
Co-authored papers 2
Soichi Ogishima
Tohoku University Graduate School of Medicine
Co-authored papers 2
Christine L Mummery
Leiden University Medical Center
Co-authored papers 2
Weonju Lee
Kyungpook National University, Kyungpook National University Hospital
Co-authored papers 2
Yohei Yonekura
RIKEN Center for Developmental Biology
Co-authored papers 2
Carsten O Daub
International Institute of Molecular and Cell Biology in Warsaw
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Release 1.2