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Author Details
Full Name
Hans-Heinrich Hoffmann
Affiliation
The Rockefeller University
ORCID
Career Start Year
2008
Papers
59
H Index
32
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36049612
IL-6/STAT3 axis dictates the PNPLA3-mediated susceptibility to non-alcoholic fatty liver disease.
J Hepatol
2023
38076887
Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection.
bioRxiv
2023
38096415
Heteromultimeric sarbecovirus receptor binding domain immunogens primarily generate variant-specific neutralizing antibodies.
Proc Natl Acad Sci U S A
2023
37563206
Author Correction: Cell-impermeable staurosporine analog targets extracellular kinases to inhibit HSV and SARS-CoV-2.
Commun Biol
2023
36992196
Characterization of Live-Attenuated Powassan Virus Vaccine Candidates Identifies an Efficacious Prime-Boost Strategy for Mitigating Powassan Virus Disease in a Murine Model.
Vaccines (Basel)
2023
36538032
Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.
Science
2023
36565697
Clonal replacement sustains long-lived germinal centers primed by respiratory viruses.
Cell
2023
34896863
Flavivirus-host interactions: an expanding network of proviral and antiviral factors.
Curr Opin Virol
2022
35576468
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.
Proc Natl Acad Sci U S A
2022
35447092
Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins.
Immunity
2022
36451809
A minimally-edited mouse model for infection with multiple SARS-CoV-2 strains.
Front Immunol
2022
36245045
Cell-impermeable staurosporine analog targets extracellular kinases to inhibit HSV and SARS-CoV-2.
Commun Biol
2022
36130725
Common human genetic variants of APOE impact murine COVID-19 mortality.
Nature
2022
35132412
Conserved Neutralizing Epitopes on the N-Terminal Domain of Variant SARS-CoV-2 Spike Proteins.
bioRxiv
2022
35043109
The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies.
Res Sq
2022
33382968
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks.
Cell
2021
33544838
Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine.
J Exp Med
2021
34851166
Metabolites with SARS-CoV-2 Inhibitory Activity Identified from Human Microbiome Commensals.
mSphere
2021
34648371
Replication and single-cycle delivery of SARS-CoV-2 replicons.
Science
2021
34547765
Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy.
Nature
2021
34834920
A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry.
Viruses
2021
34075373
Fc-engineered antibody therapeutics with improved efficacy against COVID-19.
Res Sq
2021
34126625
Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection.
Nature
2021
34100013
Naturally enhanced neutralizing breadth to SARS-CoV-2 after one year.
bioRxiv
2021
33338421
TMEM41B Is a Pan-flavivirus Host Factor.
Cell
2021
33443154
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes.
Proc Natl Acad Sci U S A
2021
33442697
Self-organized stem cell-derived human lung buds with proximo-distal patterning and novel targets of SARS-CoV-2.
bioRxiv
2021
32511384
Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals.
bioRxiv
2020
33112236
Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants.
Elife
2020
33052348
TMEM41B is a pan-flavivirus host factor.
bioRxiv
2020
33052332
Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks.
bioRxiv
2020
32692348
Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses.
J Exp Med
2020
32577658
Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses.
bioRxiv
2020
32972996
Autoantibodies against type I IFNs in patients with life-threatening COVID-19.
Science
2020
32743579
Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants.
bioRxiv
2020
32709745
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology.
Proc Natl Acad Sci U S A
2020
32704094
LY6E impairs coronavirus fusion and confers immune control of viral disease.
Nat Microbiol
2020
32694732
Metabolic coessentiality mapping identifies C12orf49 as a regulator of SREBP processing and cholesterol metabolism.
Nat Metab
2020
32555388
Convergent antibody responses to SARS-CoV-2 in convalescent individuals.
Nature
2020
30643282
IFITM3 directly engages and shuttles incoming virus particles to lysosomes.
Nat Chem Biol
2019
31652305
Investigating the functional link between TMEM165 and SPCA1.
Biochem J
2019
31270247
Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines.
J Exp Med
2019
29249360
Intrinsic Immunity Shapes Viral Resistance of Stem Cells.
Cell
2018
30355490
NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus.
Cell Rep
2018
29395325
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown.
Cell
2018
29192196
A robust cell culture system supporting the complete life cycle of hepatitis B virus.
Sci Rep
2017
28329704
The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity.
Immunity
2017
29024641
Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread.
Cell Host Microbe
2017
27128351
Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies.
Virology
2016
27899441
Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion.
J Exp Med
2016
1 - 50 of 59
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Collaborators
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Rockefeller University
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Co-authored papers
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7
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Co-authored papers
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6
Kaya Bilguvar
Acibadem Mehmet Ali Aydinlar University
Co-authored papers
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The Rockefeller University
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Icahn School of Medicine at Mount Sinai
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3
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University of North Carolina
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3
Shrikant Mane
Yale School of Medicine
Co-authored papers
3
Charles M Rudin
Memorial Sloan Kettering Cancer Center
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Megan L Shaw
Icahn School of Medicine at Mount Sinai
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Brad R Rosenberg
Icahn School of Medicine at Mount Sinai
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Boston University Chobanian and Avedisian School of Medicine
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2
Steven C Almo
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