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Author Details

Raymond J Owens
University of Oxford
1986
170
49
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35867861SARS-CoV-2 triggers pericyte-mediated cerebral capillary constriction.Brain2023
37828292Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.Commun Chem2023
37087502Marine picocyanobacterial PhnD1 shows specificity for various phosphorus sources but likely represents a constitutive inorganic phosphate transporter.ISME J2023
37238687Screening of Membrane Protein Production by Comparison of Transient Expression in Insect and Mammalian Cells.Biomolecules2023
37093471High-Throughput Production and Optimization of Membrane Proteins After Expression in Mammalian Cells.Methods Mol Biol2023
36619367Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.iScience2023
35051665Structural mass spectrometry decodes domain interaction and dynamics of the full-length Human Histone Deacetylase 2.Biochim Biophys Acta Proteins Proteom2022
35858383Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes.Proc Natl Acad Sci U S A2022
36499140Chemistry towards Biology-Instruct: Snapshot.Int J Mol Sci2022
36240740GPC3-Unc5 receptor complex structure and role in cell migration.Cell2022
36385939Identification of Inhibitors of the <i>Schistosoma mansoni</i> VKR2 Kinase Domain.ACS Med Chem Lett2022
34135888Schistosomiasis Drug Discovery in the Era of Automation and Artificial Intelligence.Front Immunol2021
33483491A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses.Nat Commun2021
33536566Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.Nat Struct Mol Biol2021
34529035Crystallographic approach to fragment-based hit discovery against Schistosoma mansoni purine nucleoside phosphorylase.Biochem J2021
34552091A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19.Nat Commun2021
34433568Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals.Sci Adv2021
34631127The use of nanobodies in a sensitive ELISA test for SARS-CoV-2 Spike 1 protein.R Soc Open Sci2021
34543623Optimized expression and purification of adipose triglyceride lipase improved hydrolytic and transacylation activities in vitro.J Biol Chem2021
34653190The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif.PLoS One2021
34835020Structural Biology of Nanobodies against the Spike Protein of SARS-CoV-2.Viruses2021
34019939Temperature-dependent secretion of Zika virus envelope and non-structural protein 1 in mammalian cells for clinical applications.J Virol Methods2021
34040256Structural basis of antifolate recognition and transport by PCFT.Nature2021
34321357Architecture of cell-cell junctions in situ reveals a mechanism for bacterial biofilm inhibition.Proc Natl Acad Sci U S A2021
33950386Transient Transfection and Expression of Eukaryotic Membrane Proteins in Expi293F Cells and Their Screening on a Small Scale: Application for Structural Studies.Methods Mol Biol2021
32367362Optimization of Small-Scale Production of Zika Virus Envelope Glycoprotein by Transient Expression in HEK293 Cells for ELISA.Methods Mol Biol2020
31808997Molecular basis for GTP recognition by light-activated guanylate cyclase RhGC.FEBS J2020
33374561Human DDX17 Unwinds Rift Valley Fever Virus Non-Coding RNAs.Int J Mol Sci2020
32719005Structure of a collagen VI α3 chain VWA domain array: adaptability and functional implications of myopathy causing mutations.J Biol Chem2020
32661423Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.Nat Struct Mol Biol2020
32737466Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.Nat Struct Mol Biol2020
32793398Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19.NPJ Vaccines2020
30430727Crystal structures of VIM-1 complexes explain active site heterogeneity in VIM-class metallo-β-lactamases.FEBS J2019
31267447Overview of a High-Throughput Pipeline for Streamlining the Production of Recombinant Proteins.Methods Mol Biol2019
31250316Streamlining the production of proteins for structural biology.Biophys Rev2019
31100550The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.Mol Immunol2019
30833605Direct imaging of the recruitment and phosphorylation of S6K1 in the mTORC1 pathway in living cells.Sci Rep2019
30772423In vitro and in vivo characterization of the multiple isoforms of Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferases.Mol Biochem Parasitol2019
31048732Immunogenicity profiling of protein antigens from capsular group B Neisseria meningitidis.Sci Rep2019
31103556Characterization of a Schistosoma mansoni NDPK expressed in sexual and digestive organs.Mol Biochem Parasitol2019
30653278Insights from the crystal structure of the chicken CREB3 bZIP suggest that members of the CREB3 subfamily transcription factors may be activated in response to oxidative stress.Protein Sci2019
29247053Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action.Proc Natl Acad Sci U S A2018
30192840The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs.PLoS One2018
30114227Generation and characterisation of recombinant FMDV antibodies: Applications for advancing diagnostic and laboratory assays.PLoS One2018
30587198Optimization of Zika virus envelope protein production for ELISA and correlation of antibody titers with virus neutralization in Mexican patients from an arbovirus endemic region.Virol J2018
29580999Highly stable single-strand-specific 3'-nuclease/nucleotidase from Legionella pneumophila.Int J Biol Macromol2018
28654419Affimer proteins are versatile and renewable affinity reagents.Elife2017
28347672Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).Mol Biochem Parasitol2017
28368383Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease.Nat Med2017
29273672CD1a presentation of endogenous antigens by group 2 innate lymphoid cells.Sci Immunol2017
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Collaborators

David I Stuart
University of Oxford
Co-authored papers 49
Lester G Carter
Stanford University
Co-authored papers 6
Carol V Robinson
University of Oxford
Co-authored papers 4
Konrad B??ssow
Helmholtz Centre for Infection Research
Co-authored papers 4
P??r Nordlund
Karolinska Institutet, BioClinicum J6
Co-authored papers 4
Joel L Sussman
Weizmann Institute of Science
Co-authored papers 3
Ann W Morgan
Co-authored papers 3
Guillaume B E Stewart-Jones
Co-authored papers 3
Udo Heinemann
Max-Delbruck-Center for Molecular Medicine in the Helmholtz Association (MDC)
Co-authored papers 3
Christian Cambillau
Aix Marseille University and CNRS
Co-authored papers 3
Yoav Peleg
Weizmann Institute of Science
Co-authored papers 3
Alexander E Gorbalenya
Leiden University Medical Center
Co-authored papers 2
Renaud Vincentelli
CNRS, Aix-Marseille Universite
Co-authored papers 2
Martino Bolognesi
University of Milano
Co-authored papers 2
Dmitri I Svergun
King's College London BHF Centre for Research Excellence
Co-authored papers 2
Tamar Unger
Weizmann Institute of Science
Co-authored papers 2
Robert Kaptein
Utrecht University
Co-authored papers 2
Lucy R Wedderburn
at UCL UCLH and GOSH.
Co-authored papers 2
Opher Gileadi
Structural Genomics Consortium Karolinska Institute Stockholm Sweden.
Co-authored papers 2
Rong Xiao
School of Public Health, Capital Medical University
Co-authored papers 1
Masayori Inouye
Robert Wood Johnson Medical School, Rutgers University
Co-authored papers 1
Gaetano T Montelione
Rensselaer Polytechnic Institute
Co-authored papers 1
Ritu Shastry
Co-authored papers 1
Ann Marie Egloff
Harvard Medical School, Brigham and Women's Hospital
Co-authored papers 1
Zihe Rao
Nankai University
Co-authored papers 1
Ian A Wilson
The Scripps Research Institute, USA The Skaggs Institute for Chemical Biology
Co-authored papers 1
Kellie Cunningham
Co-authored papers 1
F W Studier
Brookhaven National Laboratory
Co-authored papers 1
Geoffrey S Waldo
Los Alamos National Laboratory
Co-authored papers 1
Yunyu Shi
University of Science & Technology of China
Co-authored papers 1
Release 1.2