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Author Details

Christian G Huber
University of Salzburg
1992
198
43
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36831382The Class IIA Histone Deacetylase (HDAC) Inhibitor TMP269 Downregulates Ribosomal Proteins and Has Anti-Proliferative and Pro-Apoptotic Effects on AML Cells.Cancers (Basel)2023
37478974Glycoproteomics of a Single Protein: Revealing Tens of Thousands of Myozyme Glycoforms by Hybrid HPLC-MS Approaches.Mol Cell Proteomics2023
37567507Quantitative and functional characterisation of extracellular vesicles after passive loading with hydrophobic or cholesterol-tagged small molecules.J Control Release2023
37455084A semi-automated hybrid HPLC-MS approach for in-depth characterization of intact non-covalent heterodimer glycoforms of gonadotropin biopharmaceuticals.Anal Chim Acta2023
36982466Legumain Functions as a Transient TrkB Sheddase.Int J Mol Sci2023
36510116Unambiguous Identification of Glucose-Induced Glycation in mAbs and other Proteins by NMR Spectroscopy.Pharm Res2023
35168327Glycosphingolipid-Glycan Signatures of Acute Myeloid Leukemia Cell Lines Reflect Hematopoietic Differentiation.J Proteome Res2022
35398993A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation.J Extracell Vesicles2022
35491043At-line quantitative profiling of monoclonal antibody products during bioprocessing using HPLC-MS.Anal Chim Acta2022
36437554EVAnalyzer: High content imaging for rigorous characterisation of single extracellular vesicles using standard laboratory equipment and a new open-source ImageJ/Fiji plugin.J Extracell Vesicles2022
36239533Unambiguous identification of α-Gal epitopes in intact monoclonal antibodies by NMR spectroscopy.MAbs2022
35920326The Fluorescent Enzyme Cascade Detects Low Abundance Protein Modifications Suitable for the Assembly of Functionally Annotated Modificatome Databases.Chembiochem2022
36154055Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases.J Med Chem2022
34913539Overexpression of UDP-sugar pyrophosphorylase leads to higher sensitivity towards galactose, providing new insights into the mechanisms of galactose toxicity in plants.Plant J2022
35203448Synergy of Human Platelet-Derived Extracellular Vesicles with Secretome Proteins Promotes Regenerative Functions.Biomedicines2022
33475951Detecting aspartate isomerization and backbone cleavage after aspartate in intact proteins by NMR spectroscopy.J Biomol NMR2021
35008838Proteolytic Profiling of Streptococcal Pyrogenic Exotoxin B (SpeB) by Complementary HPLC-MS Approaches.Int J Mol Sci2021
34943829Scalable Enrichment of Immunomodulatory Human Acute Myeloid Leukemia Cell Line-Derived Extracellular Vesicles.Cells2021
34854455The nanotopography of SiO<sub>2</sub> particles impacts the selectivity and 3D fold of bound allergens.Nanoscale2021
34438494Multiomics assessment in Enchytraeus crypticus exposed to Ag nanomaterials (Ag NM300K) and ions (AgNO<sub>3</sub>) - Metabolomics, proteomics (&amp; transcriptomics).Environ Pollut2021
34831278Integrated <i>N</i>- and <i>O</i>-Glycomics of Acute Myeloid Leukemia (AML) Cell Lines.Cells2021
34445776Simultaneous Monitoring of Monoclonal Antibody Variants by Strong Cation-Exchange Chromatography Hyphenated to Mass Spectrometry to Assess Quality Attributes of Rituximab-Based Biotherapeutics.Int J Mol Sci2021
34288669Exploring the Chemical Space of Protein Glycosylation in Noncovalent Protein Complexes: An Expedition along Different Structural Levels of Human Chorionic Gonadotropin by Employing Mass Spectrometry.Anal Chem2021
32398793Platform independent protein-based cell-of-origin subtyping of diffuse large B-cell lymphoma in formalin-fixed paraffin-embedded tissue.Sci Rep2020
33453986Hydrogen/deuterium exchange memory NMR reveals structural epitopes involved in IgE cross-reactivity of allergenic lipid transfer proteins.J Biol Chem2020
33151990Rituximab-specific DNA aptamers are able to selectively recognize heat-treated antibodies.PLoS One2020
33149258Identification and characterization of the proteolytic flagellin from the common freshwater bacterium Hylemonella gracilis.Sci Rep2020
33093535Towards middle-up analysis of polyclonal antibodies: subclass-specific N-glycosylation profiling of murine immunoglobulin G (IgG) by means of HPLC-MS.Sci Rep2020
32691086Exploring sample preparation and data evaluation strategies for enhanced identification of host cell proteins in drug products of therapeutic antibodies and Fc-fusion proteins.Anal Bioanal Chem2020
32774209Development, characterization, and application of a 2-Compartment system to investigate the impact of pH inhomogeneities in large-scale CHO-based processes.Eng Life Sci2020
32576205Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells.Cell Commun Signal2020
33013833<i>In silico</i> Design of Phl p 6 Variants With Altered Fold-Stability Significantly Impacts Antigen Processing, Immunogenicity and Immune Polarization.Front Immunol2020
32866262Dissecting the Helicobacter pylori-regulated transcriptome of B cells.Pathog Dis2020
32530275Identification and Quantification of Oxidation Products in Full-Length Biotherapeutic Antibodies by NMR Spectroscopy.Anal Chem2020
32503348Proteins and Molecular Pathways Relevant for the Malignant Properties of Tumor-Initiating Pancreatic Cancer Cells.Cells2020
32180781Phosphoglucomutase Is Not the Target for Galactose Toxicity in Plants.Front Plant Sci2020
32496655A Simple Strategy to Eliminate Hexosylation Bias in the Relative Quantification of N-Glycosylation in Biopharmaceuticals.Angew Chem Int Ed Engl2020
30668249Dilute-and-shoot analysis of therapeutic monoclonal antibody variants in fermentation broth: a method capability study.MAbs2019
31654938Boiling down the cysteine-stabilized LTP fold - loss of structural and immunological integrity of allergenic Art v 3 and Pru p 3 as a consequence of irreversible lanthionine formation.Mol Immunol2019
31398922Untargeted Metabolomics Reveals Molecular Effects of Ketogenic Diet on Healthy and Tumor Xenograft Mouse Models.Int J Mol Sci2019
30710098Aptamers as quality control tool for production, storage and biosimilarity of the anti-CD20 biopharmaceutical rituximab.Sci Rep2019
30737614The NMR signature of gluconoylation: a frequent N-terminal modification of isotope-labeled proteins.J Biomol NMR2019
29453229Crystal Structure of Plant Legumain Reveals a Unique Two-Chain State with pH-Dependent Activity Regulation.Plant Cell2018
29933707The Enchytraeus crypticus stress metabolome - CuO NM case study.Nanotoxicology2018
30179456Monitoring of Deamidation and Lanthionine Formation in Recombinant Mugwort Allergen by Capillary Zone Electrophoresis (CZE)-UV and Transient Capillary Isotachophoresis-CZE-Electrospray Ionization-TOF-MS.Anal Chem2018
30095222The Proteome of Enchytraeus crypticus-Exposure to CuO Nanomaterial and CuCl<sub>2</sub> -in Pursue of a Mechanistic Interpretation.Proteomics2018
29582994Analytical Cascades of Enzymes for Sensitive Detection of Structural Variations in Protein Samples.Anal Chem2018
29642431The Recombinant Inhibitor of DNA Binding Id2 Forms Multimeric Structures via the Helix-Loop-Helix Domain and the Nuclear Export Signal.Int J Mol Sci2018
29443976How many human proteoforms are there?Nat Chem Biol2018
29712889Native mass spectrometry combined with enzymatic dissection unravels glycoform heterogeneity of biopharmaceuticals.Nat Commun2018
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Collaborators

Peter J Oefner
Institute of Functional Genomics, University of Regensburg
Co-authored papers 23
Oliver Kohlbacher
Max Planck Institute for Developmental Biology
Co-authored papers 13
Therese Wohlschlager
University of Salzburg
Co-authored papers 10
Knut Reinert
Institut fur Informatik, Freie Universitat Berlin
Co-authored papers 9
Dirk Strunk
Cell Therapy Institute, Paracelsus Medical University (PMU)
Co-authored papers 3
Erdmann Rapp
Co-authored papers 3
Wenzhong Xiao
Stanford University
Co-authored papers 3
Katharina Schallmoser
Paracelsus Medical University
Co-authored papers 3
Rainer Spang
University of Regensburg
Co-authored papers 2
Karl Mechtler
IMP-Institute of Molecular Pathology
Co-authored papers 1
Ruedi Aebersold
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Mathias Uhl??n
KTH Royal Institute of Technology
Co-authored papers 1
Vamsi K Mootha
Broad Institute of MIT and Harvard
Co-authored papers 1
James J Pesavento
Saint Mary's College of California
Co-authored papers 1
Steven M Patrie
Northwestern University
Co-authored papers 1
Michael C Jewett
Northwestern University
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Carolyn R Bertozzi
Stanford University
Co-authored papers 1
Ole N Jensen
VILLUM Center for Bioanalytical Sciences, University of Southern Denmark
Co-authored papers 1
Nicolas L Young
Baylor College of Medicine, USA Center for Precision Environmental Health
Co-authored papers 1
Mark S Baker
Macquarie University
Co-authored papers 1
Michael Altenbuchinger
University Medical Center Gottingen
Co-authored papers 1
Sharon J Pitteri
Stanford University
Co-authored papers 1
Jeremy Gunawardena
Harvard Medical School
Co-authored papers 1
David R Walt
Brigham and Women's Hospital
Co-authored papers 1
Donatella Carpi
Joint Research Centre (JRC)
Co-authored papers 1
Alexander R Ivanov
Barnett Institute of Chemical and Biological Analysis, Northeastern University
Co-authored papers 1
Michael J MacCoss
University of Washington
Co-authored papers 1
Lennart Martens
Co-authored papers 1
Laura L Kiessling
Massachusetts Institute of Technology
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Release 1.2