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Author Details
Full Name
Pedro E Cruz
Affiliation
College of Medicine, University of Florida
ORCID
Career Start Year
1994
Papers
102
H Index
36
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36535953
Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance.
NPJ Parkinsons Dis
2022
33128896
Anti-tau scFvs Targeted to the Cytoplasm or Secretory Pathway Variably Modify Pathology and Neurodegenerative Phenotypes.
Mol Ther
2021
33741985
Il-10 signaling reduces survival in mouse models of synucleinopathy.
NPJ Parkinsons Dis
2021
33614654
Consistent Long-Term Therapeutic Efficacy of Human Umbilical Cord Matrix-Derived Mesenchymal Stromal Cells After Myocardial Infarction Despite Individual Differences and Transient Engraftment.
Front Cell Dev Biol
2021
33496840
Photodynamic studies reveal rapid formation and appreciable turnover of tau inclusions.
Acta Neuropathol
2021
33957936
Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy.
Mol Neurodegener
2021
32122372
Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS.
Mol Neurodegener
2020
31903524
Intracerebral Expression of AAV-APOE4 Is Not Sufficient to Alter Tau Burden in Two Distinct Models of Tauopathy.
Mol Neurobiol
2020
33069251
Aÿ40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aÿ42 toxicity in Drosophila.
Alzheimers Res Ther
2020
30770411
rAAV-based brain slice culture models of Alzheimer's and Parkinson's disease inclusion pathologies.
J Exp Med
2019
31685865
Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus.
Sci Rep
2019
31455873
Downregulation of the human peripheral myelin protein 22 gene by miR-29a in cellular models of Charcot-Marie-Tooth disease.
Gene Ther
2019
30711010
Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph.
Alzheimers Res Ther
2019
31042463
APP-Mediated Signaling Prevents Memory Decline in Alzheimer's Disease Mouse Model.
Cell Rep
2019
30804924
The Secretome Derived From 3D-Cultured Umbilical Cord Tissue MSCs Counteracts Manifestations Typifying Rheumatoid Arthritis.
Front Immunol
2019
27864463
Increased brain hemopexin levels improve outcomes after intracerebral hemorrhage.
J Cereb Blood Flow Metab
2018
30158114
TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease.
J Exp Med
2018
30341064
High-affinity interactions and signal transduction between Aβ oligomers and TREM2.
EMBO Mol Med
2018
29208777
Short Aβ peptides attenuate Aβ42 toxicity in vivo.
J Exp Med
2018
28040463
Umbilical cord tissue-derived mesenchymal stromal cells maintain immunomodulatory and angiogenic potencies after cryopreservation and subsequent thawing.
Cytotherapy
2017
27909741
The role of epigenetic modifiers in extended cultures of functional hepatocyte-like cells derived from human neonatal mesenchymal stem cells.
Arch Toxicol
2017
27590069
Self-assembled 3D spheroids and hollow-fibre bioreactors improve MSC-derived hepatocyte-like cell maturation in vitro.
Arch Toxicol
2017
27308302
Microglia-specific targeting by novel capsid-modified AAV6 vectors.
Mol Ther Methods Clin Dev
2016
27680210
Therapeutic angiogenesis induced by human umbilical cord tissue-derived mesenchymal stromal cells in a murine model of hindlimb ischemia.
Stem Cell Res Ther
2016
24480602
The Human Umbilical Cord Tissue-Derived MSC Population UCX(®) Promotes Early Motogenic Effects on Keratinocytes and Fibroblasts and G-CSF-Mediated Mobilization of BM-MSCs When Transplanted In Vivo.
Cell Transplant
2015
26658861
Re-Opening the Critical Window for Estrogen Therapy.
J Neurosci
2015
26156074
IFN-γ promotes Ͽ phosphorylation without affecting mature tangles.
FASEB J
2015
26152284
Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice.
Mol Neurodegener
2015
26064137
What Makes Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells Superior Immunomodulators When Compared to Bone Marrow Derived Mesenchymal Stromal Cells?
Stem Cells Int
2015
25904780
A human monoclonal IgG that binds aβ assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo.
J Neurosci
2015
25943527
Human amniocyte-derived cells are a promising cell host for adenoviral vector production under serum-free conditions.
Biotechnol J
2015
25956381
Three-dimensional spheroid cell culture of umbilical cord tissue-derived mesenchymal stromal cells leads to enhanced paracrine induction of wound healing.
Stem Cell Res Ther
2015
25619653
IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior.
Neuron
2015
25228069
Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice.
Mol Ther
2015
24411922
Human umbilical cord tissue-derived mesenchymal stromal cells attenuate remodeling after myocardial infarction by proangiogenic, antiapoptotic, and endogenous cell-activation mechanisms.
Stem Cell Res Ther
2014
25350374
Independent relationship between amyloid precursor protein (APP) dimerization and γ-secretase processivity.
PLoS One
2014
25075157
Effects of umbilical cord tissue mesenchymal stem cells (UCX®) on rat sciatic nerve regeneration after neurotmesis injuries.
J Stem Cells Regen Med
2014
24620716
Complex relationships between substrate sequence and sensitivity to alterations in γ-secretase processivity induced by γ-secretase modulators.
Biochemistry
2014
24352661
γ-Secretase processing and effects of γ-secretase inhibitors and modulators on long Aβ peptides in cells.
J Biol Chem
2014
24438697
Towards an advanced therapy medicinal product based on mesenchymal stromal cells isolated from the umbilical cord tissue: quality and safety data.
Stem Cell Res Ther
2014
23324136
The role of human umbilical cord tissue-derived mesenchymal stromal cells (UCX®) in the treatment of inflammatory arthritis.
J Transl Med
2013
23825679
Capsid serotype and timing of injection determines AAV transduction in the neonatal mice brain.
PLoS One
2013
23774650
Unbiased screen reveals ubiquilin-1 and -2 highly associated with huntingtin inclusions.
Brain Res
2013
23714769
Conformational templating of α-synuclein aggregates in neuronal-glial cultures.
Mol Neurodegener
2013
22526458
Regulation of ENaC biogenesis by the stress response protein SERP1.
Pflugers Arch
2012
23285814
Thymus mastichina: chemical constituents and their anti-cancer activity.
Nat Prod Commun
2012
22934827
Downstream processing of lentiviral vectors: releasing bottlenecks.
Hum Gene Ther Methods
2012
20693405
N-glycosylation augmentation of the cystic fibrosis epithelium improves Pseudomonas aeruginosa clearance.
Am J Respir Cell Mol Biol
2011
21590397
Manufacturing of retroviruses.
Methods Mol Biol
2011
21420496
Cellular fusion for gene delivery to SCA1 affected Purkinje neurons.
Mol Cell Neurosci
2011
1 - 50 of 102
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Center for Translational Research in Neurodegenerative Disease, University of Florida
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Yona Levites
Emory University School of Medicine
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Andrew Li
Center for Translational Research in Neurodegenerative Disease, University of Florida
Co-authored papers
5
Christopher Janus
College of Medicine, University of Florida
Co-authored papers
4
Brenda D Moore
College of Medicine, University of Florida
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4
Christian Mueller
Co-authored papers
4
Cory C Funk
Institute for Systems Biology
Co-authored papers
3
Nadia DiNunno
College of Medicine, Penn State College of Medicine
Co-authored papers
3
Dennis W Dickson
Mayo Clinic Jacksonville
Co-authored papers
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Amanda N Sacino
Johns Hopkins University School of Medicine
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3
Qiushi Tang
Co-authored papers
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Anupam Agarwal
Co-authored papers
3
Nathan D Price
Institute for Systems Biology
Co-authored papers
3
Nil??fer Ertekin-Taner
Mayo Clinic
Co-authored papers
2
Diego E Rincon-Limas
University of Florida
Co-authored papers
2
Jonas S Almeida
National Cancer Institute (NCI)
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2
Hongdong Li
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Xue Wang
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Mariet Allen
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