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Author Details

Kieran Wynne
University College Dublin
2002
81
29
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36894174Analysis of context-specific KRAS-effector (sub)complexes in Caco-2 cells.Life Sci Alliance2023
37627169Proteomic Mapping of the Interactome of KRAS Mutants Identifies New Features of RAS Signalling Networks and the Mechanism of Action of Sotorasib.Cancers (Basel)2023
37511580Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells.Int J Mol Sci2023
37981907Ergolide mediates anti-cancer effects on metastatic uveal melanoma cells and modulates their cellular and extracellular vesicle proteomes.Open Res Eur2023
37536521Preomic profile of BxPC-3 cells after treatment with BRC4.J Proteomics2023
37045861Interactome dynamics of RAF1-BRAF kinase monomers and dimers.Sci Data2023
37280313The protein and miRNA profile of plasma extracellular vesicles (EVs) can distinguish feline mammary adenocarcinoma patients from healthy feline controls.Sci Rep2023
36858853Investigating serum extracellular vesicles in Cystic Fibrosis.J Cyst Fibros2023
36711246Whole-cell energy modeling reveals quantitative changes of predicted energy flows in RAS mutant cancer cell lines.iScience2023
35246154Reconstruction and analysis of a large-scale binary Ras-effector signaling network.Cell Commun Signal2022
35341915Machine learning based prediction and the influence of complement - Coagulation pathway proteins on clinical outcome: Results from the NEURAPRO trial.Brain Behav Immun2022
35761023A comparative analysis of extracellular vesicles (EVs) from human and feline plasma.Sci Rep2022
36671585Disease-Gene Networks of Skin Pigmentation Disorders and Reconstruction of Protein-Protein Interaction Networks.Bioengineering (Basel)2022
36104561Control of cell state transitions.Nature2022
36307392Evidence that complement and coagulation proteins are mediating the clinical response to omega-3 fatty acids: A mass spectrometry-based investigation in subjects at clinical high-risk for psychosis.Transl Psychiatry2022
30635638Complement pathway changes at age 12 are associated with psychotic experiences at age 18 in a longitudinal population-based study: evidence for a role of stress.Mol Psychiatry2021
33684717Enriching antimicrobial peptides from milk hydrolysates using pectin/alginate food-gels.Food Chem2021
33523897Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer.Sci Adv2021
34884982The Extracellular Matrix Environment of Clear Cell Renal Cell Carcinoma Determines Cancer Associated Fibroblast Growth.Cancers (Basel)2021
34161660Nonvalvular atrial fibrillation patients anticoagulated with rivaroxaban compared with warfarin exhibit reduced circulating extracellular vesicles with attenuated pro-inflammatory protein signatures.J Thromb Haemost2021
32161586Impaired Airway Epithelial Barrier Integrity in Response to <i>Stenotrophomonas maltophilia</i> Proteases, Novel Insights Using Cystic Fibrosis Bronchial Epithelial Cell Secretomics.Front Immunol2020
32683515Triphenyl phosphate is a selective PPARγ modulator that does not induce brite adipogenesis in vitro and in vivo.Arch Toxicol2020
32672416Human bone marrow stem/stromal cell osteogenesis is regulated via mechanically activated osteocyte-derived extracellular vesicles.Stem Cells Transl Med2020
32671099Comparative Platelet Releasate Proteomic Profiling of Acute Coronary Syndrome versus Stable Coronary Artery Disease.Front Cardiovasc Med2020
30318839The Platelet Releasate is Altered in Human Pregnancy.Proteomics Clin Appl2019
30779601Unravelling the transcriptional responses of TGF-β: Smad3 and EZH2 constitute a regulatory switch that controls neuroretinal epithelial cell fate specification.FASEB J2019
31080155ApoE elevation is associated with the persistence of psychotic experiences from age 12 to age 18: Evidence from the ALSPAC birth cohort.Schizophr Res2019
31076518SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.Mol Cell Proteomics2019
29036721Blood-Based Protein Changes in Childhood Are Associated With Increased Risk for Later Psychotic Disorder: Evidence From a Nested Case-Control Study of the ALSPAC Longitudinal Birth Cohort.Schizophr Bull2018
29932309Platelet Releasate Proteome Profiling Reveals a Core Set of Proteins with Low Variance between Healthy Adults.Proteomics2018
30067985PHD3 Regulates p53 Protein Stability by Hydroxylating Proline 359.Cell Rep2018
30431433Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma.Elife2018
29606589The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells.Mol Cell2018
29628311A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.Mol Cell2018
29510447Proteomic Analysis Reveals a Strong Association of β-Catenin With Cadherin Adherens Junctions in Resting Human Platelets.Proteomics2018
29428747Peptidomic screening of bitter and nonbitter casein hydrolysate fractions for insulinogenic peptides.J Dairy Sci2018
27989643SerpinI2 (pancpin) is an inhibitory serpin targeting pancreatic elastase and chymotrypsin.Biochim Biophys Acta Proteins Proteom2017
28362488Serotonin Transporter Associated Protein Complexes Are Enriched in Synaptic Vesicle Proteins and Proteins Involved in Energy Metabolism and Ion Homeostasis.ACS Chem Neurosci2017
28384443Effect of platelet-derived β-thromboglobulins on coagulation.Thromb Res2017
28317260Comparative proteomic analysis of trophoblast cell models reveals their differential phenotypes, potential uses, and limitations.Proteomics2017
28554894Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.EMBO J2017
28794469Targeting the PI3K/Akt/mTOR signalling pathway in Cystic Fibrosis.Sci Rep2017
28762254The Effects of Prenatal Iron Deficiency and Risperidone Treatment on the Rat Frontal Cortex:â¿¿ A Proteomic Analysis.Proteomics2017
26948626In silico and in vitro analyses of the angiotensin-I converting enzyme inhibitory activity of hydrolysates generated from crude barley (Hordeum vulgare) protein concentrates.Food Chem2016
26607048Proteome and pathway effects of chronic haloperidol treatment in mouse hippocampus.Proteomics2016
27634302Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.Mol Cell Proteomics2016
27898073Proteomic analysis of the postsynaptic density implicates synaptic function and energy pathways in bipolar disorder.Transl Psychiatry2016
27480532Understanding the physiological roles of polyhydroxybutyrate (PHB) in Rhodospirillum rubrum S1 under aerobic chemoheterotrophic conditions.Appl Microbiol Biotechnol2016
27329341Analysis of the proteins associated with platelet detergent resistant membranes.Proteomics2016
26977433Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation.Data Brief2016
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Collaborators

Gerard Cagney
Conway Institute of Biomedical and Biomolecular Sciences, University College Dublin
Co-authored papers 31
Patricia B Maguire
Co-authored papers 15
Giorgio Oliviero
University College Dublin
Co-authored papers 11
Eugene T Dillon
Conway Institute of Biomolecular and Biomedical Research
Co-authored papers 8
Adrian P Bracken
Smurfit Institute of Genetics, Trinity College Dublin
Co-authored papers 6
Gundula Streubel
Smurfit Institute of Genetics, Trinity College Dublin
Co-authored papers 5
Pauline M Rudd
Co-authored papers 4
Ariane Watson
University College Dublin
Co-authored papers 4
Michael J Dunn
Co-authored papers 3
Darren J Fitzpatrick
Smurfit Institute of Genetics, Trinity College Dublin
Co-authored papers 3
Desmond J Fitzgerald
Co-authored papers 3
Karsten Hokamp
Smurfit Institute of Genetics, Trinity College of Dublin
Co-authored papers 2
Sriganesh Jammula
Early Cancer Institute, Hutchison Research Centre, University of Cambridge
Co-authored papers 2
Ian B Hickie
Co-authored papers 2
Merete Nordentoft
Co-authored papers 2
Diego Pasini
European Institute of Oncology IRCCS
Co-authored papers 2
Eleanor Glancy
Smurfit Institute of Genetics, Trinity College Dublin
Co-authored papers 2
Gian Luca Negri
British Columbia Cancer Research Institute
Co-authored papers 2
Darran P O'Connor
UCD Conway Institute, University College Dublin
Co-authored papers 2
William M Gallagher
All-Island Cancer Research Institute, UCD Conway Institute, University College Dublin
Co-authored papers 2
Eric Conway
Conway Institute, University College Dublin
Co-authored papers 2
Andrea Scelfo
Institut Curie, PSL Research University, CNRS
Co-authored papers 2
Aoife McLysaght
Smurfit Institute of Genetics, Trinity College Dublin
Co-authored papers 1
Jun Qi
Dana-Farber Cancer Institute
Co-authored papers 1
Alan Mackay-Sim
Northern Clinical School, Sydney Medical School, University of Sydney
Co-authored papers 1
Philip Doran
Co-authored papers 1
Andrew Emili
Boston University School of Medicine, Boston University
Co-authored papers 1
James E Bradner
Co-authored papers 1
Rachel McCole
Smurfit Institute of Genetics, Trinity College Dublin
Co-authored papers 1
Catherine Egan
Moorfields Eye Hospital NHS Foundation Trust
Co-authored papers 1
Release 1.2