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Author Details

John Guatelli
University of California San Diego, USA VA San Diego Healthcare System
1978
103
46
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36577173Nef enhances HIV-1 replication and infectivity independently of SERINC5 in CEM T cells.Virology2023
36992361A Conserved Acidic Residue in the C-Terminal Flexible Loop of HIV-1 Nef Contributes to the Activity of SERINC5 and CD4 Downregulation.Viruses2023
35017099Comparative Analysis of T-Cell Spatial Proteomics and the Influence of HIV Expression.Mol Cell Proteomics2022
34003853Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity.PLoS Pathog2021
33930332Functional landscape of SARS-CoV-2 cellular restriction.Mol Cell2021
33581863Corrigendum to "Sensitivity to monoclonal antibody 447-52D and an open env trimer conformation correlate poorly with inhibition of HIV-1 infectivity by SERINC5" [Virology 2020 548, 73-81].Virology2021
34843601A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor.PLoS Pathog2021
32719457Structural basis of CD4 downregulation by HIV-1 Nef.Nat Struct Mol Biol2020
31941773A Conserved Acidic-Cluster Motif in SERINC5 Confers Partial Resistance to Antagonism by HIV-1 Nef.J Virol2020
33228686Inconsistent reversal of HIV-1 latency ex vivo by antigens of HIV-1, CMV, and other infectious agents.Retrovirology2020
33024967Functional Landscape of SARS-CoV-2 Cellular Restriction.bioRxiv2020
32838948Sensitivity to monoclonal antibody 447-52D and an open env trimer conformation correlate poorly with inhibition of HIV-1 infectivity by SERINC5.Virology2020
30867310The C-Terminal End of HIV-1 Vpu Has a Clade-Specific Determinant That Antagonizes BST-2 and Facilitates Virion Release.J Virol2019
31480747Plasma Membrane-Associated Restriction Factors and Their Counteraction by HIV-1 Accessory Proteins.Cells2019
30158294An N-Glycosylated Form of SERINC5 Is Specifically Incorporated into HIV-1 Virions.J Virol2018
30135209Phosphoserine acidic cluster motifs bind distinct basic regions on the μ subunits of clathrin adaptor protein complexes.J Biol Chem2018
28606917Quantitative Temporal Viromics of an Inducible HIV-1 Model Yields Insight to Global Host Targets and Phospho-Dynamics Associated with Protein Vpr.Mol Cell Proteomics2017
28878074Cooperation of the Ebola Virus Proteins VP40 and GP<sub>1,2</sub> with BST2 To Activate NF-κB Independently of Virus-Like Particle Trapping.J Virol2017
28504462Endocytic activity of HIV-1 Vpu: Phosphoserine-dependent interactions with clathrin adaptors.Traffic2017
27253329Non-degradative Ubiquitination of Protein Kinases.PLoS Comput Biol2016
27356902The Evolutionary Histories of Antiretroviral Proteins SERINC3 and SERINC5 Do Not Support an Evolutionary Arms Race in Primates.J Virol2016
25416754Long-term persistence of zoster vaccine efficacy.Clin Infect Dis2015
26676780Pharmacologic Inhibition of Nedd8 Activation Enzyme Exposes CD4-Induced Epitopes within Env on Cells Expressing HIV-1.J Virol2015
25759385Membrane Anchoring by a C-terminal Tryptophan Enables HIV-1 Vpu to Displace Bone Marrow Stromal Antigen 2 (BST2) from Sites of Viral Assembly.J Biol Chem2015
24155399Effects of alpha interferon treatment on intrinsic anti-HIV-1 immunity in vivo.J Virol2014
24843023Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1.Elife2014
24574397Activities of transmitted/founder and chronic clade B HIV-1 Vpu and a C-terminal polymorphism specifically affecting virion release.J Virol2014
23221546Stimulation of NF-κB activity by the HIV restriction factor BST2.J Virol2013
23953889HIV latency and integration site placement in five cell-based models.Retrovirology2013
23633406Safety of zoster vaccine in elderly adults following documented herpes zoster.J Infect Dis2013
22072710HIV-1 Vpu protein antagonizes innate restriction factor BST-2 via lipid-embedded helix-helix interactions.J Biol Chem2012
23047923Interferon-induced SCYL2 limits release of HIV-1 by triggering PP2A-mediated dephosphorylation of the viral protein Vpu.Sci Signal2012
22705789Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef.Nat Struct Mol Biol2012
22828595Persistence of the efficacy of zoster vaccine in the shingles prevention study and the short-term persistence substudy.Clin Infect Dis2012
22315404Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo.Proc Natl Acad Sci U S A2012
20980512Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu.J Virol2011
21849457Upregulation of BST-2/Tetherin by HIV infection in vivo.J Virol2011
21813615Role of the endocytic pathway in the counteraction of BST-2 by human lentiviral pathogens.J Virol2011
21922073Misdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence.Cell Logist2011
21237475BST-2 is rapidly down-regulated from the cell surface by the HIV-1 protein Vpu: evidence for a post-ER mechanism of Vpu-action.Virology2011
20201792The Vpu protein: new concepts in virus release and CD4 down-modulation.Curr HIV Res2010
20688520BST-2/tetherin: a new component of the innate immune response to enveloped viruses.Trends Microbiol2010
20708210BST-2 mediated restriction of simian-human immunodeficiency virus.Virology2010
20529266HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment.Retrovirology2010
20585562Tetherin restricts productive HIV-1 cell-to-cell transmission.PLoS Pathog2010
20221443Direct restriction of virus release and incorporation of the interferon-induced protein BST-2 into HIV-1 particles.PLoS Pathog2010
20147723How innate immunity can inhibit the release of HIV-1 from infected cells.N Engl J Med2010
19478868Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking.PLoS Pathog2009
19929170Antiviral activity of the interferon-induced cellular protein BST-2/tetherin.AIDS Res Hum Retroviruses2009
20012522Interactions of viral protein U (Vpu) with cellular factors.Curr Top Microbiol Immunol2009
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Collaborators

Douglas D Richman
Center for AIDS Research, University of California San Diego
Co-authored papers 25
Charlotte A Stoneham
University of California
Co-authored papers 14
Mary K Lewinski
University of California
Co-authored papers 13
Rajendra Kumar-Singh
University of California San Diego
Co-authored papers 10
Thomas R Gingeras
Stanley Institute for Cognitive Genomics
Co-authored papers 7
Peter W Ramirez
California State University Long Beach
Co-authored papers 6
Xiaofei Jia
University of Massachusetts Dartmouth
Co-authored papers 6
Satish K Pillai
Vitalant Research Institute, USA University of California san francisco
Co-authored papers 6
Marissa Suarez
VA San Diego Healthcare System
Co-authored papers 5
Susan J Little
Co-authored papers 5
Myron J Levin
Co-authored papers 4
Carol A Kauffman
Co-authored papers 4
Marie R Griffin
Vanderbilt University Medical Center
Co-authored papers 4
Aaron L Oom
New York University Grossman School of Medicine
Co-authored papers 4
Paul D De Jesus
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 3
Sumit K Chanda
The Scripps Research Institute
Co-authored papers 3
Lars Pache
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 3
David J Gonzalez
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California
Co-authored papers 3
Jacob M Wozniak
The Scripps Research Institute
Co-authored papers 3
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 3
Laura Martin-Sancho
The Scripps Research Institute
Co-authored papers 2
Matthew Urbanowski
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Mark H Ellisman
National Center for Microscopy and Imaging Research, University of California
Co-authored papers 2
Megan L Shaw
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Ariel Rodriguez-Frandsen
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Davey M Smith
University of California San Diego
Co-authored papers 2
Joel O Wertheim
University of California
Co-authored papers 2
Dexter Pratt (CM4AI)
UC San Diego
Co-authored papers 2
Judd F Hultquist
Northwestern University Feinberg School of Medicine
Co-authored papers 2
Otto O Yang
Co-authored papers 2
Release 1.2