Author details

Full Name

Douglas R Lowy

Affiliation

ORCID

Career Start Year

1967

Papers

350

H Index

119

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37040086	Estimating human papillomavirus vaccine efficacy from a single-arm trial: proof-of-principle in the Costa Rica Vaccine Trial.	J Natl Cancer Inst	2023
36423642	Prospects for preventing cancer with anti-microbial prophylactic vaccines.	Cell Host Microbe	2023
37267580	The Childhood Cancer Data Initiative: Using the Power of Data to Learn From and Improve Outcomes for Every Child and Young Adult With Pediatric Cancer.	J Clin Oncol	2023
37264688	SARS-CoV-2 IgG Spike antibody levels and avidity in natural infection or following vaccination with mRNA-1273 or BNT162b2 vaccines.	Hum Vaccin Immunother	2023
36943829	Risk of and duration of protection from SARS-CoV-2 reinfection assessed with real-world data.	PLoS One	2023
37191544	Assay Harmonization Study To Measure Immune Response to SARS-CoV-2 Infection and Vaccines: a Serology Methods Study.	Microbiol Spectr	2023
36620882	HPV42, a "Low-Risk" Type, and Digital Papillary Adenocarcinoma.	Cancer Discov	2023
36730407	The NIH-led research response to COVID-19.	Science	2023
35285688	Chondroitin Sulfate Proteoglycans Are De Facto Cellular Receptors for Human Papillomavirus 16 under High Serum Conditions.	J Virol	2022
35709811	Precancerous cervical lesions caused by non-vaccine-preventable HPV types after vaccination with the bivalent AS04-adjuvanted HPV vaccine: an analysis of the long-term follow-up study from the randomised Costa Rica HPV Vaccine Trial.	Lancet Oncol	2022
35700704	Cancer vaccines.	Cancer Cell	2022
36222529	Selection, Characterization, Calibration, and Distribution of the U.S. Serology Standard for Anti-SARS-CoV-2 Antibody Detection.	J Clin Microbiol	2022
35640980	Performance of Cervical Screening a Decade Following HPV Vaccination: The Costa Rica Vaccine Trial.	J Natl Cancer Inst	2022
36343305	Treating Smoking in Cancer Patients: An Essential Component of Cancer Care-The New National Cancer Institute Tobacco Control Monograph.	JCO Oncology Practice	2022
35749366	Harnessing anti-cytomegalovirus immunity for local immunotherapy against solid tumors.	Proc Natl Acad Sci U S A	2022
35351898	HPV16 infection decreases vaccine-induced HPV16 antibody avidity: the CVT trial.	NPJ Vaccines	2022
35333502	Clinical Evidence Generation During a Pandemic: Lessons Learned for Sustaining Progress.	Cancer J	2022
34857420	Rationale and design of a double-blind randomized non-inferiority clinical trial to evaluate one or two doses of vaccine against human papillomavirus including an epidemiologic survey to estimate vaccine efficacy: The Costa Rica ESCUDDO trial.	Vaccine	2022
35233580	Duration of Protection Against SARS-CoV-2 Reinfection and Associated Risk of Reinfection Assessed with Real-World Data.	medRxiv	2022
35019677	A Trans-Governmental Collaboration to Independently Evaluate SARS-CoV-2 Serology Assays.	Microbiol Spectr	2022
34648947	Impact of Joint Lung Cancer Screening and Cessation Interventions Under the New Recommendations of the U.S. Preventive Services Task Force.	Journal of Thoracic Oncology	2022
34727930	The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1.	Molecular Cancer	2021
33798439	The next horizon in precision oncology: Proteogenomics to inform cancer diagnosis and treatment.	Cell	2021
33625463	Association of SARS-CoV-2 Seropositive Antibody Test With Risk of Future Infection.	JAMA Intern Med	2021
33200359	An Introduction to Virus Infections and Human Cancer.	Recent Results Cancer Res	2021
34862367	Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein.	Nat Commun	2021
32606003	Cancer-Associated Point Mutations in the Tumor Suppressor and Other Rho-GAPs Occur Frequently and Are Associated with Decreased Function.	Cancer Research	2020
32091594	Evaluation of Durability of a Single Dose of the Bivalent HPV Vaccine: The CVT Trial.	J Natl Cancer Inst	2020
33354682	Real-world data suggest antibody positivity to SARS-CoV-2 is associated with a decreased risk of future infection.	medRxiv	2020
32786189	The Effect of Advances in Lung-Cancer Treatment on Population Mortality.	New England Journal of Medicine	2020
32610080	The COVID-19 Serology Studies Workshop: Recommendations and Challenges.	Immunity	2020
31409902	DLC1 deficiency and YAP signaling drive endothelial cell contact inhibition of growth and tumorigenesis.	Oncogene	2019
30635393	A Prime-Pull-Amplify Vaccination Strategy To Maximize Induction of Circulating and Genital-Resident Intraepithelial CD8<sup>+</sup> Memory T Cells.	J Immunol	2019
31092566	Human Papillomavirus 16 Capsids Mediate Nuclear Entry during Infection.	J Virol	2019
31308216	SRC and ERK cooperatively phosphorylate DLC1 and attenuate its Rho-GAP and tumor suppressor functions.	Journal of Cell Biology	2019
29773874	Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment.	Nat Commun	2018
28954299	Durability of Protection Afforded by Fewer Doses of the HPV16/18 Vaccine: The CVT Trial.	J Natl Cancer Inst	2018
30273184	The Partnership for Accelerating Cancer Therapies.	Cancer J	2018
29159802	Adenovirus vector-based prime-boost vaccination via heterologous routes induces cervicovaginal CD8<sup>+</sup> T cell responses against HPV16 oncoproteins.	Int J Cancer	2018
29366703	Evidence for single-dose protection by the bivalent HPV vaccine-Review of the Costa Rica HPV vaccine trial and future research studies.	Vaccine	2018
29325819	Explanations for the high potency of HPV prophylactic vaccines.	Vaccine	2018
29202196	Effects of DLC1 Deficiency on Endothelial Cell Contact Growth Inhibition and Angiosarcoma Progression.	Journal of the National Cancer Institute	2018
28250129	Interferon Gamma Prevents Infectious Entry of Human Papillomavirus 16 via an L2-Dependent Mechanism.	J Virol	2017
28497074	Efficient Production of Papillomavirus Gene Delivery Vectors in Defined InÂ Vitro Reactions.	Mol Ther Methods Clin Dev	2017
28402946	DLC1: a tumor suppressor that regulates Rho signaling.	Oncotarget	2017
28876435	Preventing Cancer and Other Diseases Caused by Human Papillomavirus Infection: 2017 Lasker-DeBakey Clinical Research Award.	JAMA	2017
29208378	Implementing the Cancer Moonshot and beyond.	Lancet Oncology, The	2017
29114068	Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1.	J Cell Biol	2017
27653561	Toward a Shared Vision for Cancer Genomic Data.	N Engl J Med	2016
26892991	Impact of human papillomavirus (HPV) 16 and 18 vaccination on prevalent infections and rates of cervical lesions after excisional treatment.	Am J Obstet Gynecol	2016