Author details

Full Name

Marinella Gebbia

Affiliation

University of Toronto

ORCID

Career Start Year

1989

Papers

H Index

Expertise

CM4AI Collaborator

Nevan J Krogan (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36798224	Systematically testing human HMBS missense variants to reveal mechanism and pathogenic variation.	bioRxiv	2023
37729906	Systematically testing human HMBS missense variants to reveal mechanism and pathogenic variation.	Am J Hum Genet	2023
34214447	Shifting landscapes of human MTHFR missense-variant effects.	Am J Hum Genet	2021
32296183	A reference map of the human binary protein interactome.	Nature	2020
31668799	Highly Combinatorial Genetic Interaction Analysis Reveals a Multi-Drug Transporter Influence Network.	Cell Syst	2020
32939983	Systematic analysis of bypass suppression of essential genes.	Mol Syst Biol	2020
29807908	Mapping DNA damage-dependent genetic interactions in yeast via party mating and barcode fusion genetics.	Mol Syst Biol	2018
29163459	CRISPR/Cas9 System as a Valuable Genome Editing Tool for Wine Yeasts with Application to Decrease Urea Production.	Front Microbiol	2017
27107012	Pooled-matrix protein interaction screens using Barcode Fusion Genetics.	Mol Syst Biol	2016
27811238	Exploring genetic suppression interactions on a global scale.	Science	2016
27800551	Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles.	ACS Cent Sci	2016
25667933	Genes required for survival in microgravity revealed by genome-wide yeast deletion collections cultured during spaceflight.	Biomed Res Int	2015
26353928	Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death.	Oncotarget	2015
25832785	Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells.	Apoptosis	2015
24723613	Mapping the cellular response to small molecules using chemogenomic fitness signatures.	Science	2014
23109428	Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation.	Mol Cell Biol	2013
23658529	A compendium of nucleosome and transcript profiles reveals determinants of chromatin architecture and transcription.	PLoS Genet	2013
23202731	Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors.	J Clin Invest	2013
22183606	Genomic approaches for determining nucleosome occupancy in yeast.	Methods Mol Biol	2012
23240084	Chromatin is an ancient innovation conserved between Archaea and Eukarya.	Elife	2012
23123093	Timing of transcriptional quiescence during gametogenesis is controlled by global histone H3K4 demethylation.	Dev Cell	2012
22727066	Identification of yeast genes that confer resistance to chitosan oligosaccharide (COS) using chemogenomics.	BMC Genomics	2012
22253786	Mitochondrial electron transport is the cellular target of the oncology drug elesclomol.	PLoS One	2012
21698101	Design, synthesis and characterization of a highly effective inhibitor for analog-sensitive (as) kinases.	PLoS One	2011
22384333	A global perspective of the genetic basis for carbonyl stress resistance.	G3 (Bethesda)	2011
22094260	Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.	Cancer Cell	2011
22102822	Multiple means to the same end: the genetic basis of acquired stress resistance in yeast.	PLoS Genet	2011
21942931	Nucleosome-coupled expression differences in closely-related species.	BMC Genomics	2011
21896781	Evolution of nucleosome occupancy: conservation of global properties and divergence of gene-specific patterns.	Mol Cell Biol	2011
21655328	Design, synthesis, and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signaling in yeast.	PLoS One	2011
18688276	Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast.	PLoS Genet	2008
19111667	A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters.	Mol Cell	2008
17314980	Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map.	Nature	2007
16872538	PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs.	BMC Bioinformatics	2006
15610744	Proteasome involvement in the repair of DNA double-strand breaks.	Mol Cell	2004
11959836	A complex syndrome of left-right axis, central nervous system and axial skeleton defects in Zic3 mutant mice.	Development	2002
9916847	Left-right axis malformations associated with mutations in ACVR2B, the gene for human activin receptor type IIB.	Am J Med Genet	1999
9354794	X-linked situs abnormalities result from mutations in ZIC3.	Nat Genet	1997
9311745	A submicroscopic deletion in Xq26 associated with familial situs ambiguus.	Am J Hum Genet	1997
8784260	Major histocompatibility complex class II molecule expression on muscle cells is regulated by differentiation: implications for the immunopathogenesis of muscle autoimmune diseases.	J Neuroimmunol	1996
8873667	Failure to detect connexin43 mutations in 38 cases of sporadic and familial heterotaxy.	Circulation	1996
7580241	Lack of mRNA and dystrophin expression in DMD patients three months after myoblast transfer.	Neuromuscul Disord	1995
7720070	A cluster of sulfatase genes on Xp22.3: mutations in chondrodysplasia punctata (CDPX) and implications for warfarin embryopathy.	Cell	1995
7647783	Cloning of the gene for ocular albinism type 1 from the distal short arm of the X chromosome.	Nat Genet	1995
7935525	Fetus-like dystrophin expression and other cytoskeletal protein abnormalities in centronuclear myopathies.	Muscle Nerve	1994
8263549	Dystrophin abnormalities in Duchenne and Becker dystrophy carriers: correlation with cytoskeletal proteins and myosins.	J Neurol	1993
8329891	Very small dystrophin molecule in a family with a mild form of Becker dystrophy.	Neuromuscul Disord	1993
2787543	Interactions of manganese with human brain glutathione-S-transferase.	Toxicology	1989

1 - 48 of 48

Jiewei Xu

Quantitative Biosciences Institute (QBI), University of California san francisco

Career Start Year 2012

Number of shared co-authors 9

Tomasz Zemojtel

Berlin Institute of Health (BIH)

Career Start Year 2001

Number of shared co-authors 0

J??rg Grigull

York University

Career Start Year 2000

Number of shared co-authors 12

Peter White

The Ohio State University

Career Start Year 2000

Number of shared co-authors 2

Braden Boone

HudsonAlpha Institute for Biotechnology

Career Start Year 1999

Number of shared co-authors 0

Shawn Levy

HudsonAlpha Institute for Biotechnology

Career Start Year 1999

Number of shared co-authors 1

Amy Hin Yan Tong

University of Toronto

Career Start Year 1999

Number of shared co-authors 32

Lars M Steinmetz

Stanford University

Career Start Year 1998

Number of shared co-authors 16

Edwin Cuppen

Hartwig Medical Foundation

Career Start Year 1997

Number of shared co-authors 1

Bernhard Suter

Baylor College of Medicine

Career Start Year 1997

Number of shared co-authors 17

Patrice Menard

Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark

Career Start Year 1996

Number of shared co-authors 14

Ping Liang

College of Chemistry and Chemical Engineering, Hunan University

Career Start Year 1995

Number of shared co-authors 0

Manuel L Gonzalez-Garay

College of Medicine, University of Arizona

Career Start Year 1992

Number of shared co-authors 1

Patrick S Tarpey

Wellcome Trust Sanger Institute

Career Start Year 1992

Number of shared co-authors 2

Zugen Chen

David Geffen School of Medicine, University of California los angeles

Career Start Year 1992

Number of shared co-authors 0

Janos Demeter

Stanford University School of Medicine, Center for Clinical Sciences Research

Career Start Year 1991

Number of shared co-authors 3

Yasushi Okazaki

Intractable Disease Research Center, Graduate School of Medicine, Juntendo University

Career Start Year 1989

Number of shared co-authors 3

Donna M Muzny

Baylor College of Medicine

Career Start Year 1988

Number of shared co-authors 7

Sarah B Pierce

University of Washington

Career Start Year 1987

Number of shared co-authors 0

Richard A Gibbs

Baylor College of Medicine

Career Start Year 1987

Number of shared co-authors 7

Kwang-Lae Hoe

Chungnam National University

Career Start Year 1987

Number of shared co-authors 9

Eric S Lander

Vanderbilt-Ingram Cancer Center, Vanderbilt University

Career Start Year 1986

Number of shared co-authors 11

Andreas Gnirke

The Center for Genome Architecture, Baylor College of Medicine

Career Start Year 1986

Number of shared co-authors 0

Jiannis Ragoussis

McGill University

Career Start Year 1986

Number of shared co-authors 2

Hediye Erdjument-Bromage

Neuroscience Institute, NYU Grossman School of Medicine

Career Start Year 1984

Number of shared co-authors 3

Marian J A Groot Koerkamp

Princess Maxima Center for Pediatric Oncology Research

Career Start Year 1983

Number of shared co-authors 3

Michael Snyder

Stanford University

Career Start Year 1981

Number of shared co-authors 17

Richard M Myers

HudsonAlpha Institute for Biotechnology

Career Start Year 1980

Number of shared co-authors 4

Norma Neff

Stanford University

Career Start Year 1974

Number of shared co-authors 2

Arthur L Beaudet

Baylor College of Medicine

Career Start Year 1968

Number of shared co-authors 2

row(s) 1 - 30 of 30

Frederick P Roth

University of Toronto

Co-authored papers 10

Lawrence E Heisler

Ontario Institute for Cancer Research

Co-authored papers 5

Marcela Gronda

Princess Margaret Cancer Centre

Co-authored papers 4

Aaron D Schimmer

Princess Margaret Cancer Centre

Co-authored papers 4

Patrick Aloy

Institucio Catalana de Recerca i Estudis Avancats (ICREA)

Co-authored papers 4

Anna Y Lee

Ontario Institute for Cancer Research

Co-authored papers 4

Jeffrey L Wrana

Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital

Co-authored papers 3

Gary D Bader

University of Toronto

Co-authored papers 3

Iain M Wallace

Novartis Institutes for BioMedical Research

Co-authored papers 3

Alessandro Datti

University of Perugia

Co-authored papers 3

Grant W Brown

University of Toronto, 1 King's College Circle

Co-authored papers 3

Rose Hurren

Princess Margaret Cancer Centre

Co-authored papers 3

Harm van Bakel

Icahn School of Medicine at Mount Sinai

Co-authored papers 3

Jack F Greenblatt

College Street, University of Toronto

Co-authored papers 3

Brenda J Andrews

University of Toronto

Co-authored papers 3

Andrew Emili

Boston University School of Medicine, Boston University

Co-authored papers 3

Charles Boone

University of Toronto

Co-authored papers 3

Nevan J Krogan (CM4AI)

University of California San Francisco

Co-authored papers 3

Carles Pons

Co-authored papers 3

Jeffrey A Towbin

University of Tennessee Health Science Center

Co-authored papers 2

Sanie Mnaimneh

University of Toronto

Co-authored papers 2

Nozomu Yachie

The University of British Columbia

Co-authored papers 2

Michael Costanzo

Co-authored papers 2

Igor Stagljar

University of Toronto, Canada Mediterranean Institute for Life Sciences

Co-authored papers 2

David Schlessinger

NIH/National Institute of Ageing

Co-authored papers 2

Giovanni Battista Ferrero

Co-authored papers 2

John E Dick

Princess Margaret Cancer Centre, University Health Network

Co-authored papers 2

Jason Moffat

University of Toronto

Co-authored papers 2

Timothy R Hughes

University of Toronto

Co-authored papers 2

Laure Fr??sard

Invitae Corporation

Co-authored papers 2

1 - 30

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