Author details

Full Name

Leonid Kruglyak

Affiliation

ORCID

Career Start Year

1987

Papers

176

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36879982	Heritable Cas9-induced nonhomologous recombination in .		2023
37642275	Genetics and biology of coloration in reptiles: the curious case of the Lemon Frost geckos.		2023
36711988	Cas9-induced nonhomologous recombination in .		2023
37076734	Insufficient evidence for non-neutrality of synonymous mutations.	Nature	2023
33939799	Retrospective Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Symptomatic Patients Prior to Widespread Diagnostic Testing in Southern California.	Clin Infect Dis	2022
35650439	Island-specific evolution of a sex-primed autosome in a sexual planarian.	Nature	2022
35379194	Genomic epidemiology of the Los Angeles COVID-19 outbreak and the early history of the B.1.43 strain in the USA.	BMC Genomics	2022
36326816	Genome-wide base editor screen identifies regulators of protein abundance in yeast.	eLife	2022
35717313	Towards synthetic PETtrophy: Engineering Pseudomonas putida for concurrent polyethylene terephthalate (PET) monomer metabolism and PET hydrolase expression.	Microbial Cell Factories	2022
36459978	A minimal role for synonymous variation in human disease.	Am J Hum Genet	2022
36525401	Exploring the genetic architecture of protein secretion in Komagataella phaffii (Pichia pastoris) for biotechnology applications.		2022
35005055	Lower Severe Acute Respiratory Syndrome Coronavirus 2 Viral Shedding Following Coronavirus Disease 2019 Vaccination Among Healthcare Workers in Los Angeles, California.	Open Forum Infect Dis	2021
33479156	Ancient balancing selection maintains incompatible versions of the galactose pathway in yeast.	Science	2021
34166378	Genetics of white color and iridophoroma in "Lemon Frost" leopard geckos.	PLoS Genet	2021
33734084	Whole-organism eQTL mapping at cellular resolution with single-cell sequencing.	eLife	2021
34211145	Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples.	Nat Biomed Eng	2021
33417886	Ubiquitous Selfish Toxin-Antidote Elements in Caenorhabditis Species.	Current Biology	2021
34570108	Planarian Ovary Dissection for Ultrastructural Analysis and Antibody Staining.	J Vis Exp	2021
33179598	Systematic identification of cis-regulatory variants that cause gene expression differences in a yeast cross.	Elife	2020
32886546	Toxin-Antidote Elements Across the Tree of Life.	Annual Review of Genetics	2020
31213597	Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk.	Nature Communications	2019
31647408	Rare variants contribute disproportionately to quantitative trait variation in yeast.	eLife	2019
31761530	Screening Human Embryos for Polygenic Traits Has Limited Utility.	Cell	2019
30504363	The Genetic Basis of Mutation Rate Variation in Yeast.	Genetics	2019
31283753	Analysis of the genetic basis of height in large Jewish nuclear families.	PLoS Genetics	2019
31021269	How Low Can You Go?	CRISPR Journal	2018
30014850	Genetics of -regulatory variation in gene expression.	eLife	2018
29632376	Highly parallel genome variant engineering with CRISPR-Cas9.	Nat Genet	2018
28250458	Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast.	Nature Genetics	2017
28826486	Genetic variation in adaptability and pleiotropy in budding yeast.	eLife	2017
28819099	The genetic basis of natural variation in a phoretic behavior.	Nat Commun	2017
28495877	A maternal-effect selfish genetic element in .	Science	2017
28572335	A genetic signature of the evolution of loss of flight in the Galapagos cormorant.	Science	2017
27449056	The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length.	Genetics	2016
27384025	Complex Traits and Simple Systems: An Interview with Leonid Kruglyak.	Genetics	2016
27230379	CRISPR-directed mitotic recombination enables genetic mapping without crosses.	Science	2016
26942280	2015 Curt Stern Award.	American Journal of Human Genetics	2016
26537231	Genetic interactions contribute less than additive effects to quantitative trait variation in yeast.	Nature Communications	2015
25707927	The role of regulatory variation in complex traits and disease.	Nature Reviews Genetics	2015
25783854	Full-genome evolutionary histories of selfing, splitting, and selection in Caenorhabditis.	Genome Res	2015
25569670	Genetic mapping of MAPK-mediated complex traits Across S. cerevisiae.	PLoS Genetics	2015
25770127	A Powerful New Quantitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains.	G3: Genes, Genomes, Genetics	2015
25680197	A wild C. elegans strain has enhanced epithelial immunity to a natural microsporidian parasite.	PLoS Pathogens	2015
26092720	Genetics of Intraspecies Variation in Avoidance Behavior Induced by a Thermal Stimulus in Caenorhabditis elegans.	Genetics	2015
25995208	Remarkably Divergent Regions Punctuate the Genome Assembly of the Caenorhabditis elegans Hawaiian Strain CB4856.	Genetics	2015
24603560	Genetic basis of metabolome variation in yeast.	PLoS Genet	2014
25340754	Genetic influences on translation in yeast.	PLoS Genet	2014
25521586	Genetic basis of haloperidol resistance in Saccharomyces cerevisiae is complex and dose dependent.	PLoS Genetics	2014
24402228	Genetics of single-cell protein abundance variation in large yeast populations.	Nature	2014
24586193	A variant in the neuropeptide receptor npr-1 is a major determinant of Caenorhabditis elegans growth and physiology.	PLoS Genetics	2014