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Author Details

Nadia Dahmane
Weill Cornell Medical College
1994
50
31
PMIDPaper TitleJournal TitlePublished Year
37011459Leptomeningeal dissemination in pediatric brain tumors.Neoplasia2023
37054779Preclinical validation of a novel therapeutic strategy for choroid plexus carcinoma.J Control Release2023
35574596Developments in high-throughput functional epigenomics: CRISPR-single-cell assay for transposase-accessible chromatin using sequencing screens.Epigenomics2022
33903225RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons.Mol Cell Biol2021
32642711Missing diversity in brain tumor trials.Neurooncol Adv2020
31887631B7-H3 as a Prognostic Biomarker and Therapeutic Target in Pediatric central nervous system Tumors.Transl Oncol2020
32832670PET, image-guided HDAC inhibition of pediatric diffuse midline glioma improves survival in murine models.Sci Adv2020
31920606Multivariate Analysis of Preoperative Magnetic Resonance Imaging Reveals Transcriptomic Classification of <i>de novo</i> Glioblastoma Patients.Front Comput Neurosci2019
31815646Immune landscapes associated with different glioblastoma molecular subtypes.Acta Neuropathol Commun2019
29572492Radiomic MRI signature reveals three distinct subtypes of glioblastoma with different clinical and molecular characteristics, offering prognostic value beyond IDH1.Sci Rep2018
30306125Checkpoint Blockade Reverses Anergy in IL-13Rα2 Humanized scFv-Based CAR T Cells to Treat Murine and Canine Gliomas.Mol Ther Oncolytics2018
29617843In vivo evaluation of EGFRvIII mutation in primary glioblastoma patients via complex multiparametric MRI signature.Neuro Oncol2018
29422647Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α.Nat Commun2018
28852935SHP2 regulates proliferation and tumorigenicity of glioma stem cells.J Neurooncol2017
28428190<i>In Vivo</i> Detection of EGFRvIII in Glioblastoma via Perfusion Magnetic Resonance Imaging Signature Consistent with Deep Peritumoral Infiltration: The <i>Ï¿</i>-Index.Clin Cancer Res2017
28954238Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons.Cell Rep2017
26188015Imaging patterns predict patient survival and molecular subtype in glioblastoma via machine learning techniques.Neuro Oncol2016
27043280c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma.J Clin Invest2016
26578789Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes.Proc Natl Acad Sci U S A2015
24994715Pyrvinium attenuates Hedgehog signaling downstream of smoothened.Cancer Res2014
25038227NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis.Cancer Res2014
23034578Autotransplantation for renovascular hypertension in children with solitary functioning kidney.J Hum Hypertens2013
22095278RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion.Cell Death Differ2012
22513377Rp58 is essential for the growth and patterning of the cerebellum and for glutamatergic and GABAergic neuron development.Development2012
22641694Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma.J Cell Sci2012
21217079Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia.Blood2011
22199406Design, synthesis, and biological evaluation of estrone-derived hedgehog signaling inhibitors.Tetrahedron2011
21842835Stereoselective synthesis of F-ring saturated estrone-derived inhibitors of Hedgehog signaling based on cyclopamine.Org Lett2011
21905689Studies directed toward the elucidation of the pharmacophore of steroid-based Sonic Hedgehog signaling inhibitors.Org Lett2011
21712398Alternative transcription exceeds alternative splicing in generating the transcriptome diversity of cerebellar development.Genome Res2011
20103640ZNF238 is expressed in postmitotic brain cells and inhibits brain tumor growth.Cancer Res2010
20389077Differential modulation of Sonic-hedgehog-induced cerebellar granule cell precursor proliferation by the IGF signaling network.Dev Neurosci2010
19920144The full-length unprocessed hedgehog protein is an active signaling molecule.J Biol Chem2010
19057928Sonic hedgehog mutations identified in holoprosencephaly patients can act in a dominant negative manner.Hum Genet2009
19552464Design and synthesis of inhibitors of Hedgehog signaling based on the alkaloid cyclopamine.Org Lett2009
17961552Neuronal distribution of spatial in the developing cerebellum and hippocampus and its somatodendritic association with the kinesin motor KIF17.Exp Cell Res2007
17030124Sonic hedgehog signaling in forebrain development and its interactions with pathways that modify its effects.Trends Cell Biol2006
15604099Sonic hedgehog controls stem cell behavior in the postnatal and adult brain.Development2005
11823802Hedgehog-Gli signalling and the growth of the brain.Nat Rev Neurosci2002
12466855A gene expression map of human chromosome 21 orthologues in the mouse.Nature2002
12044012Gli and hedgehog in cancer: tumours, embryos and stem cells.Nat Rev Cancer2002
11520659Embryonic regionalization of the neocortex.Mech Dev2001
11378387Wnt signals are targets and mediators of Gli function.Curr Biol2001
11748155The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis.Development2001
10375501Sonic hedgehog regulates the growth and patterning of the cerebellum.Development1999
10440859Getting a-head of the organizer: anterior-posterior patterning of the forebrain.Bioessays1999
9503011Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome.Genomics1998
9349822Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours.Nature1997
7568099Down syndrome-critical region contains a gene homologous to Drosophila sim expressed during rat and human central nervous system development.Proc Natl Acad Sci U S A1995
81882883.6-Mb genomic and YAC physical map of the Down syndrome chromosome region on chromosome 21.Genomics1994
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Collaborators

Co-authored papers 12
Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania
Co-authored papers 10
The Wistar Institute
Co-authored papers 7
University of Pennsylvania
Co-authored papers 5
Massachusetts General Hospital
Co-authored papers 4
New York Presbyterian and Memorial Sloan Kettering Cancer Center
Co-authored papers 4
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Foundational Immunology, AbbVie Cambridge Research Center
Co-authored papers 3
Richards Medical Research Laboratories (S.B.)
Co-authored papers 3
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Weill Cornell Medical Center, NewYork Presbyterian Hospital
Co-authored papers 3
Max Planck Institute for Molecular Genetics
Co-authored papers 3
The Wistar Institute
Co-authored papers 2
Feil Family Brain and Mind Research Institute.
Co-authored papers 2
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 2
Weill Cornell Medical College
Co-authored papers 2
NewYork-Presbyterian Hospital - Weill Cornell Medicine
Co-authored papers 2
Broad Institute of MIT and Harvard
Co-authored papers 1
The Wistar Institute
Co-authored papers 1
University of Pennsylvania Department of Pathology & Laboratory Medicine
Co-authored papers 1
University of Pennsylvania School of Medicine
Co-authored papers 1
Hospital of the University of Pennsylvania
Co-authored papers 1
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Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 1
Center for Intelligent Imaging (ci2), University of California san francisco
Co-authored papers 1
Center for Personal Dynamic Regulomes, Stanford University
Co-authored papers 1
Gladstone Institute of Neurological Disease
Co-authored papers 1
Max Planck Institute for Molecular Genetics
Co-authored papers 1
Dartmouth College Geisel School of Medicine, Princeton University, University of Colorado Anschutz Medical Campus, University of Pennsylvania Perelman School of Medicine
Co-authored papers 1