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Author Details

Mohsan Saeed
Boston University Chobanian and Avedisian School of Medicine
2007
59
24
PMIDPaper TitleJournal TitlePublished Year
36263066Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron.bioRxiv2023
37664626Plant flavonoid inhibition of SARS-CoV-2 main protease and viral replication.iScience2023
37499664High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.Cell Chem Biol2023
37534130Isogenic human trophectoderm cells demonstrate the role of <i>NDUFA4</i> and associated variants in ZIKV infection.iScience2023
37477426SARS-CoV-2 nonstructural protein 6 from Alpha to Omicron: evolution of a transmembrane protein.mBio2023
37398281The HLA-II immunopeptidome of SARS-CoV-2.bioRxiv2023
37095858Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus.iScience2023
36630998Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation.Nature2023
34668773Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection.J Virol2022
35367208Proteomic elucidation of the targets and primary functions of the picornavirus 2A protease.J Biol Chem2022
35631043Surgical Strikes on Host Defenses: Role of the Viral Protease Activity in Innate Immune Antagonism.Pathogens2022
35421379Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection.Cell Rep2022
36475798Optimized ACE2 decoys neutralize antibody-resistant SARS-CoV-2 variants through functional receptor mimicry and treat infection in vivo.Sci Adv2022
36595954HLA-I immunopeptidome profiling of human cells infected with high-containment enveloped viruses.STAR Protoc2022
36206731A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.Cell Stem Cell2022
35336942Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression.Viruses2022
33469581Fatal neuroinvasion and SARS-CoV-2 tropism in K18-hACE2 mice is partially independent on hACE2 expression.bioRxiv2021
33686143The in-vitro effect of famotidine on sars-cov-2 proteases and virus replication.Sci Rep2021
33548599Detecting SARS-CoV-2 3CLpro expression and activity using a polyclonal antiserum and a luciferase-based biosensor.Virology2021
33851170Drug repositioning candidates identified using in-silico quasi-quantum molecular simulation demonstrate reduced COVID-19 mortality in 1.5M patient records.medRxiv2021
33890572SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation.Elife2021
34379400Developing a SARS-CoV-2 Antigen Test Using Engineered Affinity Proteins.ACS Appl Mater Interfaces2021
34405680Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants.J Med Chem2021
33989385DNA templates with blocked long 3' end single-stranded overhangs (BL3SSO) promote bona fide Cas9-stimulated homology-directed repair of long transgenes into endogenous gene loci.G3 (Bethesda)2021
34013166Developing a SARS-CoV-2 Antigen Test Using Engineered Affinity Proteins.ChemRxiv2021
34260266SARS-CoV-2 Disrupts Proximal Elements in the JAK-STAT Pathway.J Virol2021
33417854Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.Mol Cell2021
32321830Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody.Proc Natl Acad Sci U S A2020
33140044SARS-CoV-2 desensitizes host cells to interferon through inhibition of the JAK-STAT pathway.bioRxiv2020
33024965SARS-CoV-2 infected cells present HLA-I peptides from canonical and out-of-frame ORFs.bioRxiv2020
33148654Liver-expressed <i>Cd302</i> and <i>Cr1l</i> limit hepatitis C virus cross-species transmission to mice.Sci Adv2020
33259812Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.Mol Cell2020
32637964SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response.bioRxiv2020
32997711Defining the proteolytic landscape during enterovirus infection.PLoS Pathog2020
32826914A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction.Nat Commun2020
32704094LY6E impairs coronavirus fusion and confers immune control of viral disease.Nat Microbiol2020
32979316SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response.Cell Stem Cell2020
32245952Stem cell-derived polarized hepatocytes.Nat Commun2020
30875640Taming a beast: lessons from the domestication of hepatitis C virus.Curr Opin Virol2019
31717338Visualization of Positive and Negative Sense Viral RNA for Probing the Mechanism of Direct-Acting Antivirals against Hepatitis C Virus.Viruses2019
30355490NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus.Cell Rep2018
29844387Male germ cells support long-term propagation of Zika virus.Nat Commun2018
30403995A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates.Cell Rep2018
30478404Identification of a Small Interface between the Methyltransferase and RNA Polymerase of NS5 that is Essential for Zika Virus Replication.Sci Rep2018
28475892Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.Cell2017
28112725Erratum: Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture.Nat Microbiol2017
27991882Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture.Nat Microbiol2016
25714714Identification, molecular cloning, and analysis of full-length hepatitis C virus transmitted/founder genotypes 1, 3, and 4.mBio2015
26266980SEC14L2 enables pan-genotype HCV replication in cell culture.Nature2015
24362933Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection.Nat Med2014
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Collaborators

Charles M Rice
Rockefeller University
Co-authored papers 25
Andrew Emili
Boston University School of Medicine, Boston University
Co-authored papers 6
Elke Mühlberger
Co-authored papers 4
Ellen L Suder
Co-authored papers 4
Pamela J Bjorkman
Co-authored papers 3
Pardis C Sabeti
Harvard University
Co-authored papers 3
Steven A Carr
Broad Institute of MIT and Harvard
Co-authored papers 3
Karl R Clauser
Co-authored papers 2
Celia A Schiffer
University of Massachusetts Chan Medical School
Co-authored papers 2
Ulrich Braunschweig
University of Toronto
Co-authored papers 2
Dima Kozakov
Stony Brook University
Co-authored papers 2
Sadhna Phanse
University of Regina
Co-authored papers 2
Dzmitry Padhorny
Co-authored papers 2
Hans-Heinrich Hoffmann
The Rockefeller University
Co-authored papers 2
Zhengming Chen
Weill Cornell Medicine and New York Presbyterian Hospital
Co-authored papers 2
Stefan Wuchty
University of Miami
Co-authored papers 2
Benjamin J Blencowe
University of Toronto
Co-authored papers 2
Qibin Qi
Co-authored papers 2
Thiago Y Oliveira
The Rockefeller University
Co-authored papers 2
Nir Hacohen
Broad Institute of MIT and Harvard
Co-authored papers 2
Henrik Molina
Co-authored papers 2
Michael Ott
Co-authored papers 1
Erica Y Jacobs
The Rockefeller University, St John's University
Co-authored papers 1
George M Shaw
Co-authored papers 1
Kenneth Gersing
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 1
Peter C Fridy
The Rockefeller University
Co-authored papers 1
Albert I Ko
Instituto Goncalo Moniz, Yale School of Public Health
Co-authored papers 1
Christopher G Chute
Brown University, Brown University Warren Alpert Medical School, Dartmouth-Hitchcock Medical Center, Harvard School of Public Health, Johns Hopkins Medicine, Mayo Clinic Minnesota
Co-authored papers 1
Maxwell L Neal
Co-authored papers 1
M Ruhul Abid
Brown University.
Co-authored papers 1
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