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Author Details

Carlos L??pez-Ot??n
Instituto Universitario de Oncologia, Universidad de Oviedo
1982
478
116
PMIDPaper TitleJournal TitlePublished Year
36374766Exercise sustains the hallmarks of health.J Sport Health Sci2023
37858983Ghrelin delays premature aging in Hutchinson-Gilford progeria syndrome.Aging Cell2023
37546695Mammary carcinoma: toward a realistic mouse model of incurable cancers.Oncoimmunology2023
37565451The secretome atlas of two mouse models of progeria.Aging Cell2023
37459465Analysis of ATG4C function <i>in vivo</i>.Autophagy2023
37182718Mechanisms of mitochondrial microRNA regulation in cardiovascular diseases.Mech Ageing Dev2023
37344100New hormone receptor-positive breast cancer mouse cell line mimicking the immune microenvironment of anti-PD-1 resistant mammary carcinoma.J Immunother Cancer2023
37100955Apoptotic cell death in disease-Current understanding of the NCCD 2023.Cell Death Differ2023
37357988Acyl coenzyme A binding protein (ACBP): An aging- and disease-relevant "autophagy checkpoint".Aging Cell2023
36749626Personalized Precision Medicine for Health Care Professionals: Development of a Competency Framework.JMIR Med Educ2023
36802457Correction: Personalized Precision Medicine for Health Care Professionals: Development of a Competency Framework.JMIR Med Educ2023
36599298Meta-hallmarks of aging and cancer.Cell Metab2023
36702832USP49 deubiquitinase regulates the mitotic spindle checkpoint and prevents aneuploidy.Cell Death Dis2023
36124427Autophagy-linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS-CoV-2 entry into human cells.EMBO J2022
36037356Comparative genomics of mortal and immortal cnidarians unveils novel keys behind rejuvenation.Proc Natl Acad Sci U S A2022
35962045Author Correction: Comparative and demographic analysis of orang-utan genomes.Nature2022
33340459Hallmarks of Health.Cell2021
33795848ATG4D is the main ATG8 delipidating enzyme in mammalian cells and protects against cerebellar neurodegeneration.Cell Death Differ2021
33707095Old Paradoxes and New Opportunities for Appetite Control in Obesity.Trends Endocrinol Metab2021
33893394Correction to: ATG4D is the main ATG8 delipidating enzyme in mammalian cells and protects against cerebellar neurodegeneration.Cell Death Differ2021
33798440Hallmarks of health.Cell2021
34459017Autophagy in major human diseases.EMBO J2021
34561231Correction: Control of Allergen-Induced Inflammation and Hyperresponsiveness by the Metalloproteinase ADAMTS-12.J Immunol2021
32342250Loss of mitochondrial ClpP, Lonp1, and Tfam triggers transcriptional induction of Rnf213, a susceptibility factor for moyamoya disease.Neurogenetics2020
34079956The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome.Nat Cancer2020
31785928Immunosuppression by Mutated Calreticulin Released from Malignant Cells.Mol Cell2020
33200421Mitochondrial Safeguard: a stress response that offsets extreme fusion and protects respiratory function via flickering-induced Oma1 activation.EMBO J2020
32820119Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage.Science2020
32729659Identification of common cardiometabolic alterations and deregulated pathways in mouse and pig models of aging.Aging Cell2020
32392217Correction: Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection.PLoS Genet2020
32475991Circulating tumor cells for comprehensive and multiregional non-invasive genetic characterization of multiple myeloma.Leukemia2020
30559458Retraction Note: NF-κB activation impairs somatic cell reprogramming in ageing.Nat Cell Biol2019
31801056Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity.Cell Metab2019
31624306Differential mechanisms of tolerance to extreme environmental conditions in tardigrades.Sci Rep2019
31547314Global Proteome of <i>LonP1</i><sup>+/-</sup> Mouse Embryonal Fibroblasts Reveals Impact on Respiratory Chain, but No Interdependence between Eral1 and Mitoribosomes.Int J Mol Sci2019
31399598Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics.Nat Commun2019
31597163The U1 spliceosomal RNA is recurrently mutated in multiple cancers.Nature2019
31422903Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity.Cell Metab2019
31444470Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction.Cell Res2019
31332389Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice.Nat Med2019
31303548Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging.Cell Stem Cell2019
31045254Moving Frailty Toward Clinical Practice: NIA Intramural Frailty Science Symposium Summary.J Am Geriatr Soc2019
30778239Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome.Nat Med2019
30808006Withdrawal: Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3.J Biol Chem2019
30808005Withdrawal: Identification and characterization of human archaemetzincin-1 and -2, two novel members of a family of metalloproteases widely distributed in Archaea.J Biol Chem2019
30808004Withdrawal: Identification of human aminopeptidase O, a novel metalloprotease with structural similarity to aminopeptidase B and leukotriene A<sub>4</sub> hydrolase.J Biol Chem2019
30808003Withdrawal: Identification and characterization of human and mouse ovastacin: A novel metalloproteinase similar to hatching enzymes from arthropods, birds, amphibians, and fish.J Biol Chem2019
30808002Withdrawal: Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy.J Biol Chem2019
30808001Withdrawal: Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteins.J Biol Chem2019
30808000Withdrawal: Identification, characterization, and intracellular processing of ADAM-TS12, a novel human disintegrin with a complex structural organization involving multiple thrombospondin-1 repeats.J Biol Chem2019
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Collaborators

University of Oviedo
Co-authored papers 68
Instituto Universitario de Oncologia, Universidad de Oviedo
Co-authored papers 64
Institute for Biomedical Research August Pi I Sunyer
Co-authored papers 41
Instituto Universitario de Oncologia (IUOPA), Universidad de Oviedo
Co-authored papers 24
Universitat Autonoma de Barcelona
Co-authored papers 11
Weizmann Institute of Science
Co-authored papers 10
Universitat de Barcelona (UB)
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University of British Columbia
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Institucio Catalana de Recerca i Estudis Avancats (ICREA)
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Institute of Informatics and Data Sciences, University of Missouri
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Lunenfeld-Tanenbaum Research Institute
Co-authored papers 7
Sidra Medical Center
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Universite de Paris, Sorbonne Universite, Inserm U8, Institut Universitaire de France
Co-authored papers 7
Josep Carreras Leukaemia Research Institute (IJC)
Co-authored papers 6
University of Washington
Co-authored papers 6
Spain Universitat de Barcelona (UB)
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Barcelona Institute of Science and Technology (BIST)
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European Bioinformatics Institute
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University of California san francisco
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Naomi Berrie Diabetes Center, Columbia University Irving Medical Center
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Albert Einstein College of Medicine
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The University of Edinburgh
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Skane University Hospital, Lund University
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University of Washington
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Wellcome Trust Sanger Institute
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University of Washington School of Medicine
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Oncode Institute
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