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Full Name
Bin Wu
Affiliation
University of Pennsylvania
ORCID
Career Start Year
2005
Papers
48
H Index
26
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36797475
Stiff matrix induces exosome secretion to promote tumour growth.
Nat Cell Biol
2023
37805922
Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity.
Cell Rep
2023
37898620
A phosphoinositide switch mediates exocyst recruitment to multivesicular endosomes for exosome secretion.
Nat Commun
2023
37696852
Single-molecule imaging reveals distinct elongation and frameshifting dynamics between frames of expanded RNA repeats in C9ORF72-ALS/FTD.
Nat Commun
2023
37162943
A Rapid Inducible RNA Decay system reveals fast mRNA decay in P-bodies.
bioRxiv
2023
35835783
HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8<sup>+</sup> T-cell infiltration into tumors.
Nat Commun
2022
32132202
Visualizing the translation and packaging of HIV-1 full-length RNA.
Proc Natl Acad Sci U S A
2020
31913283
ULK1 phosphorylates Exo70 to suppress breast cancer metastasis.
Nat Commun
2020
28489961
The role of Exo70 in exocytosis and beyond.
Small GTPases
2019
30082468
Fluorescence Imaging Methods to Investigate Translation in Single Cells.
Cold Spring Harb Perspect Biol
2019
31072814
Endosidin2-14 Targets the Exocyst Complex in Plants and Fungal Pathogens to Inhibit Exocytosis.
Plant Physiol
2019
31110057
Retargeting of macroH2A following mitosis to cytogenetic-scale heterochromatic domains.
J Cell Biol
2019
30532003
Author Correction: PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas.
Nature
2019
29345990
Imaging mRNA In Vivo, from Birth to Death.
Annu Rev Biophys
2018
30089911
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response.
Nature
2018
29061650
Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation.
J Cell Biol
2017
28246185
Polarized Exocytosis.
Cold Spring Harb Perspect Biol
2017
26951800
Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells.
J Immunol
2016
26607451
Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis.
Proc Natl Acad Sci U S A
2016
27791158
Glutamate-induced RNA localization and translation in neurons.
Proc Natl Acad Sci U S A
2016
27313041
Translation dynamics of single mRNAs in live cells and neurons.
Science
2016
25535387
Activation of Rab8 guanine nucleotide exchange factor Rabin8 by ERK1/2 in response to EGF signaling.
Proc Natl Acad Sci U S A
2015
26360028
Biochemical analysis of Rabin8, the guanine nucleotide exchange factor for Rab8.
Methods Cell Biol
2015
26475863
Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer.
J Biol Chem
2015
26140598
Quantifying Protein-mRNA Interactions in Single Live Cells.
Cell
2015
26240175
The Exocyst at a Glance.
J Cell Sci
2015
25877922
Synonymous modification results in high-fidelity gene expression of repetitive protein and nucleotide sequences.
Genes Dev
2015
25800835
Kinetic activation of Rab8 guanine nucleotide exchange factor Rabin8 by Rab11.
Methods Mol Biol
2015
24458642
Single β-actin mRNA detection in neurons reveals a mechanism for regulating its translatability.
Science
2014
24284074
RalA promotes a direct exocyst-Par6 interaction to regulate polarity in neuronal development.
J Cell Sci
2014
24402470
Background free imaging of single mRNAs in live cells using split fluorescent proteins.
Sci Rep
2014
23276537
Time-integrated fluorescence cumulant analysis and its application in living cells.
Methods Enzymol
2013
22266909
Regulation of local expression of cell adhesion and motility-related mRNAs in breast cancer cells by IMP1/ZBP1.
J Cell Sci
2012
22948660
β-Actin mRNA compartmentalization enhances focal adhesion stability and directs cell migration.
Genes Dev
2012
22735544
Fluorescence fluctuation spectroscopy enables quantitative imaging of single mRNAs in living cells.
Biophys J
2012
21192730
Determining antibody stoichiometry using time-integrated fluorescence cumulant analysis.
J Phys Chem B
2011
21512033
Real-time observation of transcription initiation and elongation on an endogenous yeast gene.
Science
2011
21242078
Modern fluorescent proteins and imaging technologies to study gene expression, nuclear localization, and dynamics.
Curr Opin Cell Biol
2011
20142515
Heterospecies partition analysis reveals binding curve and stoichiometry of protein interactions in living cells.
Proc Natl Acad Sci U S A
2010
21502409
Nuclear physics: quantitative single-cell approaches to nuclear organization and gene expression.
Cold Spring Harb Symp Quant Biol
2010
20580971
Observing protein interactions and their stoichiometry in living cells by brightness analysis of fluorescence fluctuation experiments.
Methods Enzymol
2010
20212155
Monomeric red fluorescent proteins with a large Stokes shift.
Proc Natl Acad Sci U S A
2010
19254556
Fluorescence fluctuation spectroscopy on viral-like particles reveals variable gag stoichiometry.
Biophys J
2009
19289064
Fluorescence fluctuation spectroscopy of mCherry in living cells.
Biophys J
2009
18065475
Fluorescence correlation spectroscopy of finite-sized particles.
Biophys J
2008
16815900
Dual-color time-integrated fluorescence cumulant analysis.
Biophys J
2006
15596506
Dual-color photon-counting histogram.
Biophys J
2005
16055549
Time-integrated fluorescence cumulant analysis in fluorescence fluctuation spectroscopy.
Biophys J
2005
1 - 48 of 48
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