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Author Details

Carlo Condello
UCSF Weill Institute for Neurosciences, University of California san francisco
2007
33
18
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36927157EMBER multidimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains.Proc Natl Acad Sci U S A2023
38014268<i>De novo</i> Design of Peptides that Bind Specific Conformers of α-Synuclein.bioRxiv2023
37847596Amyloid β Proteoforms Elucidated by Quantitative LC/MS in the 5xFAD Mouse Model of Alzheimer's Disease.J Proteome Res2023
37235776Total Chemical Synthesis of Glycosylated TREM2 Ectodomain.ACS Chem Neurosci2023
37398204CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.bioRxiv2023
36624100CSF1R inhibitors induce a sex-specific resilient microglial phenotype and functional rescue in a tauopathy mouse model.Nat Commun2023
36399277Aβ and Tau Prions Causing Alzheimer's Disease.Methods Mol Biol2023
36778268EMBER multi-dimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains.bioRxiv2023
35082148Soluble TREM2 inhibits secondary nucleation of Aβ fibrillization and enhances cellular uptake of fibrillar Aβ.Proc Natl Acad Sci U S A2022
35413950Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.Nat Commun2022
36343257Aβ and tau prions feature in the neuropathogenesis of Down syndrome.Proc Natl Acad Sci U S A2022
35115402Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy.Proc Natl Acad Sci U S A2022
34961556Emergence of distinct and heterogeneous strains of amyloid beta with advanced Alzheimer's disease pathology in Down syndrome.Acta Neuropathol Commun2021
32949533Prion biology: implications for Alzheimer's disease therapeutics.Lancet Neurol2020
31010726Sex-specific Tau methylation patterns and synaptic transcriptional alterations are associated with neural vulnerability during chronic neuroinflammation.J Autoimmun2019
29169609Microglia-Mediated Neuroprotection, TREM2, and Alzheimer's Disease: Evidence From Optical Imaging.Biol Psychiatry2018
28359847Aβ propagation and strains: Implications for the phenotypic diversity in Alzheimer's disease.Neurobiol Dis2018
29728653Mapping interactions with the chaperone network reveals factors that protect against tau aggregation.Nat Struct Mol Biol2018
29311311Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease.Proc Natl Acad Sci U S A2018
28837163A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells.Nat Chem2017
29157304A novel vector for transgenesis in the rat CNS.Acta Neuropathol Commun2017
29203673Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice.Proc Natl Acad Sci U S A2017
27317802Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice.J Pharmacol Exp Ther2016
27710785TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.Neuron2016
27196974TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.Neuron2016
25630253Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques.Nat Commun2015
26224882Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains.J Pharmacol Exp Ther2015
24982137Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice.Proc Natl Acad Sci U S A2014
24982139Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients.Proc Natl Acad Sci U S A2014
22366182Minocycline attenuates microglia activation and blocks the long-term epileptogenic effects of early-life seizures.Neurobiol Dis2012
22355538Multicolor time-stamp reveals the dynamics and toxicity of amyloid deposition.Sci Rep2011
21159979CX3CR1 in microglia regulates brain amyloid deposition through selective protofibrillar amyloid-β phagocytosis.J Neurosci2010
17126305Chemokines in the MPTP model of Parkinson's disease: absence of CCL2 and its receptor CCR2 does not protect against striatal neurodegeneration.Brain Res2007
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Collaborators

Stanley B Prusiner
Weill Institute for Neurosciences, University of California San Francisco
Co-authored papers 12
William F DeGrado
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 10
Kurt Giles
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 8
Abby Oehler
Institute for Neurodegenerative Diseases, University of California san francisco
Co-authored papers 7
Erika Castillo
Institute for Neurodegenerative Diseases, University of California san francisco
Co-authored papers 4
Jan St??hr
Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 4
Thomas D Bird
University of Washington School of Medicine
Co-authored papers 4
Christopher Dirk Keene
University of Washington
Co-authored papers 4
Martin Ingelsson
Co-authored papers 3
Haifan Wu
Wichita State University
Co-authored papers 3
Stephen J DeArmond
Co-authored papers 3
Joel C Watts
University of Toronto
Co-authored papers 3
Alison M Maxwell
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 3
Lars Lannfelt
Co-authored papers 3
George A Carlson
Co-authored papers 2
Sue-Ann Mok
University of Alberta
Co-authored papers 2
Brittany N Dugger
University of California davis
Co-authored papers 2
Thomas Lemmin
Co-authored papers 2
Hyunil Jo
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 2
William W Seeley
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 2
Sumita Bhardwaj
Institute for Neurodegenerative Diseases, University of California san francisco
Co-authored papers 2
Jason E Gestwicki
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 2
Mohammad R K Mofrad
University of California Berkeley
Co-authored papers 1
Li Gan
Helen and Robert Appel Alzheimer's Disease Research Institute
Co-authored papers 1
Steven M Patrie
Northwestern University
Co-authored papers 1
Ji Jin
College of Life Sciences and Medicine, Zhejiang Sci-Tech University
Co-authored papers 1
Ana Maria Cuervo
Albert Einstein College of Medicine
Co-authored papers 1
Yaqiao Li
Harvard Medical School
Co-authored papers 1
Avi J Samelson
Institute for Neurodegenerative Diseases, University of California san francisco
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Elizabeth Head
University of California Irvine
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