Author details

Full Name

Zamal Ahmed

Affiliation

The University of Texas MD Anderson Cancer Center

ORCID

Career Start Year

1999

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36661847	Epigenetic-Metabolic Interplay in the DNA Damage Response and Therapeutic Resistance of Breast Cancer.	Cancer Res	2023
37452126	The combined action of the intracellular regions regulates FGFR2 kinase activity.	Commun Biol	2023
37328606	Regulation of microRNA expression by the adaptor protein GRB2.	Sci Rep	2023
35231400	Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state.	Mol Cell	2022
35420681	Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1.	Cancer Discov	2022
33300026	Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin.	Nucleic Acids Res	2021
33795832	Grb2 binding induces phosphorylation-independent activation of Shp2.	Commun Biol	2021
33675849	An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation.	Prog Biophys Mol Biol	2021
33636189	Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors.	Prog Biophys Mol Biol	2021
34776222	An efficient chemical screening method for structure-based inhibitors to nucleic acid enzymes targeting the DNA repair-replication interface and SARS CoV-2.	Methods Enzymol	2021
34800542	PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer.	Exp Cell Res	2021
34348893	GRB2 enforces homology-directed repair initiation by MRE11.	Sci Adv	2021
30880007	Cancer mutational burden is shaped by G4 DNA, replication stress and mitochondrial dysfunction.	Prog Biophys Mol Biol	2019
31827085	Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death.	Nat Commun	2019
31615811	Correction: An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors.	Cancer Res	2019
31040156	An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors.	Cancer Res	2019
29208567	Phosphorylation of threonine residues on Shc promotes ligand binding and mediates crosstalk between MAPK and Akt pathways in breast cancer cells.	Int J Biochem Cell Biol	2018
30061390	FGFR1-mediated protocadherin-15 loading mediates cargo specificity during intraflagellar transport in inner ear hair-cell kinocilia.	Proc Natl Acad Sci U S A	2018
28668129	What Combined Measurements From Structures and Imaging Tell Us About DNA Damage Responses.	Methods Enzymol	2017
26212011	Grb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancer.	Oncogene	2016
25795775	A novel dual kinase function of the RET proto-oncogene negatively regulates activating transcription factor 4-mediated apoptosis.	J Biol Chem	2015
26103942	Grb2 monomer-dimer equilibrium determines normal versus oncogenic function.	Nat Commun	2015
26234419	Corrigendum: Grb2 monomer-dimer equilibrium determines normal versus oncogenic function.	Nat Commun	2015
24440983	Competition between Grb2 and PlcÎ³1 for FGFR2 regulates basal phospholipase activity and invasion.	Nat Struct Mol Biol	2014
24475179	Plakophilin-3 catenin associates with the ETV1/ER81 transcription factor to positively modulate gene activity.	PLoS One	2014
23584453	Interaction with Shc prevents aberrant Erk activation in the absence of extracellular stimuli.	Nat Struct Mol Biol	2013
23758320	CD25 and CD69 induction by Î±4Î²1 outside-in signalling requires TCR early signalling complex proteins.	Biochem J	2013
23420874	Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity.	J Cell Biol	2013
22726438	Inhibition of basal FGF receptor signaling by dimeric Grb2.	Cell	2012
19735729	Direct binding of Grb2 SH3 domain to FGFR2 regulates SHP2 function.	Cell Signal	2010
20388118	T-cell receptor early signalling complex activation in response to interferon-alpha receptor stimulation.	Biochem J	2010
19153664	A complex of Shc and Ran-GTPase localises to the cell nucleus.	Cell Mol Life Sci	2009
18039182	Extracellular point mutations in FGFR2 result in elevated ERK1/2 activation and perturbation of neuronal differentiation.	Biochem J	2008
18840094	Indirect recruitment of the signalling adaptor Shc to the fibroblast growth factor receptor 2 (FGFR2).	Biochem J	2008
18373495	Extracellular point mutations in FGFR2 elicit unexpected changes in intracellular signalling.	Biochem J	2008
16219325	Distinct spatial and temporal distribution of ZAP70 and Lck following stimulation of interferon and T-cell receptors.	J Mol Biol	2005
12521378	Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and phosphoinositide 3-kinase-dependent signalling.	Biochem J	2003
11498022	Functional effects of APS and SH2-B on insulin receptor signalling.	Biochem Soc Trans	2001
10854852	The APS adapter protein couples the insulin receptor to the phosphorylation of c-Cbl and facilitates ligand-stimulated ubiquitination of the insulin receptor.	FEBS Lett	2000
10417330	APS, an adapter protein with a PH and SH2 domain, is a substrate for the insulin receptor kinase.	Biochem J	1999

1 - 40 of 40

Alexandre Rosa Campos

Sanford Burnham Prebys Medical Discovery Institute

Career Start Year 2015

Number of shared co-authors 1

Florent Dingli

Institut Curie, PSL Research University

Career Start Year 2011

Number of shared co-authors 0

Severa Bunda

Princess Margaret Cancer Centre

Career Start Year 2005

Number of shared co-authors 0

Genevi??ve Lavoie

Institute for Research in Immunology and Cancer (IRIC)

Career Start Year 2004

Number of shared co-authors 0

Natalia Jura

Cardiovascular Research Institute, University of California San Francisco

Career Start Year 2003

Number of shared co-authors 1

Irina Kalatskaya

EMD Serono Research & Development Institute, Inc. (an affiliate of Merck KGaA)

Career Start Year 2003

Number of shared co-authors 0

Shawn S-C Li

University of Western Ontario

Career Start Year 2002

Number of shared co-authors 0

Danislav S Spassov

Faculty of Pharmacy, Medical University of Sofia

Career Start Year 2001

Number of shared co-authors 0

Stephane Angers

Department of Pharmaceutical Sciences, University of Toronto

Career Start Year 1999

Number of shared co-authors 0

Rachel Toth

University of Dundee

Career Start Year 1999

Number of shared co-authors 0

Paul Taylor

Hospital for Sick Children

Career Start Year 1999

Number of shared co-authors 0

Ian Pass

Cancer Center, Sanford Burnham Prebys Medical Discovery Institute

Career Start Year 1998

Number of shared co-authors 0

Lily Jun-Shen Huang

University of Texas Southwestern Medical Center

Career Start Year 1997

Number of shared co-authors 0

Michael A White

University of Georgia

Career Start Year 1994

Number of shared co-authors 2

Jiefei Tong

Hospital for Sick Children

Career Start Year 1993

Number of shared co-authors 0

Manfred Koegl

Boehringer Ingelheim RCV GmbH & Co. KG

Career Start Year 1993

Number of shared co-authors 0

Dario R Alessi

University of Dundee

Career Start Year 1992

Number of shared co-authors 1

Andrew Freywald

College of Medicine, University of Saskatchewan

Career Start Year 1992

Number of shared co-authors 0

Ivan Dikic

Institute of Biochemistry II, Goethe University Frankfurt

Career Start Year 1992

Number of shared co-authors 4

Stephan M Feller

Institute of Molecular Medicine, Martin-Luther-University of Halle-Wittenberg

Career Start Year 1989

Number of shared co-authors 0

Kun-Liang Guan

University of California San Diego

Career Start Year 1988

Number of shared co-authors 2

Hamid Band

University of Nebraska Medical Center

Career Start Year 1985

Number of shared co-authors 1

Michael F Moran

Hospital for Sick Children, University of Toronto

Career Start Year 1985

Number of shared co-authors 0

Jorge Silvio Gutkind

Moores Cancer Center, University of California San Diego

Career Start Year 1984

Number of shared co-authors 0

Sylvain Meloche

Institute for Research in Immunology and Cancer

Career Start Year 1982

Number of shared co-authors 0

Donald L Durden

Atrium Health-Levine Cancer Institute

Career Start Year 1979

Number of shared co-authors 1

Sara A Courtneidge

Oregon Health & Science University

Career Start Year 1977

Number of shared co-authors 0

Frank McCormick

Frederick National Laboratory for Cancer Research

Career Start Year 1975

Number of shared co-authors 1

Jonathan M Backer

Albert Einstein College of Medicine

Career Start Year 1970

Number of shared co-authors 2

Tony Hunter

Salk Institute for Biological Studies

Career Start Year 1968

Number of shared co-authors 1

row(s) 1 - 30 of 30

John E Ladbury

University of Leeds

Co-authored papers 23

John A Tainer

The University of Texas MD Anderson Cancer Center

Co-authored papers 10

Stefan T Arold

Co-authored papers 4

Garth Powis

PHusis Therapeutics Inc.

Co-authored papers 3

Olivier Lichtarge

Baylor College of Medicine

Co-authored papers 2

Mien-Chie Hung

Co-authored papers 2

Guillaume Poncet-Montange

Center for the Development of Therapeutics, Broad Institute of MIT & Harvard

Co-authored papers 2

Su-Chen Huang

Industrial Technology Research Institute

Co-authored papers 1

Krishna M Sinha

The University of Texas MD Anderson Cancer Center

Co-authored papers 1

Rozita Bagheri-Yarmand

The University of Texas MD Anderson Cancer Center

Co-authored papers 1

Gordon B Mills

Knight Cancer Institute, Oregon Health and Sciences University

Co-authored papers 1

Anupama E Gururaj

National Institute of Allergy and Infectious Disease, National Institutes of Health

Co-authored papers 1

Matthew Mort

Co-authored papers 1

Yasmeen Q Rizvi

University of Texas MD Anderson Cancer Center

Co-authored papers 1

Mark A Williams

Harwell Science & Innovation Campus

Co-authored papers 1

Andrzej Joachimiak

Center for Structural Biology of Infectious Diseases, University of Chicago

Co-authored papers 1

Jun Yao

The University of Texas MD Anderson Cancer Center

Co-authored papers 1

Carolyn Tregidgo

King's College London

Co-authored papers 1

Susan P Lees-Miller

University of Calgary, 0 Hospital Drive NW

Co-authored papers 1

Oliver B??gler

American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University

Co-authored papers 1

Gilbert J Cote

The University of Texas MD Anderson Cancer Center Houston

Co-authored papers 1

Michelle D Williams

The University of Texas M. D. Anderson Cancer Center

Co-authored papers 1

Cristina Ivan

The University of Texas MD Anderson Cancer Center

Co-authored papers 1

Anil K Sood

The University of Texas MD Anderson Cancer Center