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Author Details

Kathleen A Burke
Brown University
1975
81
38
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34862761Reversible Kinetic Trapping of FUS Biomolecular Condensates.Adv Sci (Weinh)2022
35071667Mapping changes in the obesity stigma discourse through Obesity Canada: a content analysis.AIMS Public Health2021
32595275Chronic Stress Exposure Suppresses Mammary Tumor Growth and Reduces Circulating Exosome TGF-β Content via β-Adrenergic Receptor Signaling in MMTV-PyMT Mice.Breast Cancer (Auckl)2020
28921573Contralateral breast cancers: Independent cancers or metastases?Int J Cancer2018
29615433Mutation Profiling of Key Cancer Genes in Primary Breast Cancers and Their Distant Metastases.Cancer Res2018
29358076Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation.Mol Cell2018
29739933Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas.Nat Commun2018
29677513Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.Cell2018
29110152Low PTEN levels and PIK3CA mutations predict resistance to neoadjuvant lapatinib and trastuzumab without chemotherapy in patients with HER2 over-expressing breast cancer.Breast Cancer Res Treat2018
28945358Lysines in the RNA Polymerase II C-Terminal Domain Contribute to TAF15 Fibril Recruitment.Biochemistry2018
27713419Genetic analysis of microglandular adenosis and acinic cell carcinomas of the breast provides evidence for the existence of a low-grade triple-negative breast neoplasia family.Mod Pathol2017
28487443HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2<sup>+</sup> Breast Cancer.Clin Cancer Res2017
28165479Whole-genome single-cell copy number profiling from formalin-fixed paraffin-embedded samples.Nat Med2017
28153863The Landscape of Somatic Genetic Alterations in Metaplastic Breast Carcinomas.Clin Cancer Res2017
28267263Genetic analysis of uterine adenosarcomas and phyllodes tumors of the breast.Mol Oncol2017
28417598Genetic analysis of a morphologically heterogeneous ovarian endometrioid carcinoma.Histopathology2017
28319063Compromised BRCA1-PALB2 interaction is associated with breast cancer risk.Oncogene2017
29043292Phyllodes tumors with and without fibroadenoma-like areas display distinct genomic features and may evolve through distinct pathways.NPJ Breast Cancer2017
29214215Genomic and transcriptomic heterogeneity in metaplastic carcinomas of the breast.NPJ Breast Cancer2017
28513873Myxoid fibroadenomas differ from conventional fibroadenomas: a hypothesis-generating study.Histopathology2017
28718916The genetic landscape of endometrial clear cell carcinomas.J Pathol2017
28790177Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity.EMBO J2017
27925203The genetic landscape of breast carcinomas with neuroendocrine differentiation.J Pathol2017
26832993Massively parallel sequencing of phyllodes tumours of the breast reveals actionable mutations, and TERT promoter hotspot mutations and TERT gene amplification as likely drivers of progression.J Pathol2016
28721389Triple-negative breast cancer: the importance of molecular and histologic subtyping, and recognition of low-grade variants.NPJ Breast Cancer2016
28721388Massively parallel sequencing analysis of synchronous fibroepithelial lesions supports the concept of progression from fibroadenoma to phyllodes tumor.NPJ Breast Cancer2016
26592504Uterine adenosarcomas are mesenchymal neoplasms.J Pathol2016
27913435IDH2 Mutations Define a Unique Subtype of Breast Cancer with Altered Nuclear Polarity.Cancer Res2016
27491809Genetic events in the progression of adenoid cystic carcinoma of the breast to high-grade triple-negative breast cancer.Mod Pathol2016
25601683Lysine residues in the N-terminal huntingtin amphipathic α-helix play a key role in peptide aggregation.J Mass Spectrom2015
28243512The Use of Second Harmonic Generation to Image the Extracellular Matrix During Tumor Progression.Intravital2015
26603532Using second harmonic generation to predict patient outcome in solid tumors.BMC Cancer2015
26455390Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II.Mol Cell2015
26365781Enzymatically-responsive pro-angiogenic peptide-releasing poly(ethylene glycol) hydrogels promote vascularization in vivo.J Control Release2015
26149620Temporally tunable, enzymatically responsive delivery of proangiogenic peptides from poly(ethylene glycol) hydrogels.Adv Healthc Mater2015
25625899Second-harmonic generation scattering directionality predicts tumor cell motility in collagen gels.J Biomed Opt2015
24670006Curvature enhances binding and aggregation of huntingtin at lipid membranes.Biochemistry2014
23331195Amyloid-forming proteins alter the local mechanical properties of lipid membranes.Biochemistry2013
24309563The antidepressant desipramine and α2-adrenergic receptor activation promote breast tumor progression in association with altered collagen structure.Cancer Prev Res (Phila)2013
24010522Stromal matrix metalloprotease-13 knockout alters Collagen I structure at the tumor-host interface and increases lung metastasis of C57BL/6 syngeneic E0771 mammary tumor cells.BMC Cancer2013
23643759Huntingtin disrupts lipid bilayers in a polyQ-length dependent manner.Biochim Biophys Acta2013
23719905Atomic force microscopy assays for evaluating polyglutamine aggregation in solution and on surfaces.Methods Mol Biol2013
23459674Biophysical insights into how surfaces, including lipid membranes, modulate protein aggregation related to neurodegeneration.Front Neurol2013
23572526The interaction of polyglutamine peptides with lipid membranes is regulated by flanking sequences associated with huntingtin.J Biol Chem2013
23172133Second harmonic generation reveals matrix alterations during breast tumor progression.J Biomed Opt2013
22433867Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein.J Biol Chem2012
22924735Mapping the mechanical properties of cholesterol-containing supported lipid bilayers with nanoscale spatial resolution.Langmuir2012
21187152Assessing mutant huntingtin fragment and polyglutamine aggregation by atomic force microscopy.Methods2011
20375116Podocyte-specific overexpression of GLUT1 surprisingly reduces mesangial matrix expansion in diabetic nephropathy in mice.Am J Physiol Renal Physiol2010
19447279Growth deficits in a postnatal day 3 rat model of hypoxic-ischemic brain injury.Behav Brain Res2009
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Collaborators

Britta Weigelt
Memorial Sloan Kettering Cancer Center
Co-authored papers 22
Jorge S Reis-Filho
Memorial Sloan-Kettering Cancer Center
Co-authored papers 21
Felipe C Geyer
Instituto Do Cancer Do Estado de Sao Paulo
Co-authored papers 19
Salvatore Piscuoglio
University of Basel
Co-authored papers 16
Charlotte K Y Ng
University of Bern
Co-authored papers 16
Larry Norton
Memorial Sloan Kettering Cancer Center
Co-authored papers 9
Raymond S Lim
Memorial Sloan Kettering Cancer Center
Co-authored papers 9
Luciano G Martelotto
Monash University
Co-authored papers 7
Caterina Marchi??
University of Turin, Candiolo Cancer Institute, FPO-IRCCS
Co-authored papers 7
Nicolas L Fawzi
Brown University
Co-authored papers 6
Pier Selenica
Memorial Sloan Kettering Cancer Center
Co-authored papers 5
Melissa P Murray
Memorial Sloan Kettering Cancer Center
Co-authored papers 5
Hannah Y Wen
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
Robert A Soslow
Co-authored papers 4
Brian P Rubin
Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic
Co-authored papers 3
Mothaffar F Rimawi
Co-authored papers 2
Rahul Kumar
Roswell Park Comprehensive Cancer Center
Co-authored papers 2
Arnaud Da Cruz Paula
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Nadeem Riaz
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Veronica H Ryan
Co-authored papers 2
Tari A King
Co-authored papers 2
Charles Kent Osborne
Co-authored papers 2
Huei-Chi Wen
Co-authored papers 2
Susan G Hilsenbeck
Co-authored papers 2
Ho Yee Joyce Fung
University of Texas Southwestern Medical Center
Co-authored papers 1
Paul J van Diest
University Medical Center Utrecht
Co-authored papers 1
Jonine L Bernstein
Co-authored papers 1
Michael F Berger
Co-authored papers 1
Ingrid A Mayer
Vanderbilt University Medical Center
Co-authored papers 1
Matthew P Goetz
Mayo Clinic
Co-authored papers 1
Release 1.2