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Author Details

Larry S Schlesinger
Texas Biomedical Research Institute
1984
212
62
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37066199A new tractable method for generating Human Alveolar Macrophage Like cells in vitro to study lung inflammatory processes and diseases.bioRxiv2023
37288969A new tractable method for generating human alveolar macrophage-like cells <i>in vitro</i> to study lung inflammatory processes and diseases.mBio2023
37000865Activation of transcription factor CREB in human macrophages by Mycobacterium tuberculosis promotes bacterial survival, reduces NF-kB nuclear transit and limits phagolysosome fusion by reduced necroptotic signaling.PLoS Pathog2023
37196159Acute inflammation alters lung lymphocytes and potentiates innate-like behavior in young mouse lung CD8 T cells, resembling lung CD8 T cells from old mice.J Leukoc Biol2023
35055170Host- and Age-Dependent Transcriptional Changes in <i>Mycobacterium tuberculosis</i> Cell Envelope Biosynthesis Genes after Exposure to Human Alveolar Lining Fluid.Int J Mol Sci2022
35821836The Impact of Aging on the Lung Alveolar Environment, Predetermining Susceptibility to Respiratory Infections.Front Aging2022
35460553The Aging Human Lung Mucosa: A Proteomics Study.J Gerontol A Biol Sci Med Sci2022
35862216Isoniazid and rifapentine treatment effectively reduces persistent M. tuberculosis infection in macaque lungs.J Clin Invest2022
36405707Systems biology approaches to investigate the role of granulomas in TB-HIV coinfection.Front Immunol2022
36558885Differential Role of Type 2 Diabetes as a Risk Factor for Tuberculosis in the Elderly versus Younger Adults.Pathogens2022
36297211Resistance and Susceptibility Immune Factors at Play during <i>Mycobacterium tuberculosis</i> Infection of Macrophages.Pathogens2022
36257939Retraction Note: Ornithine-A urea cycle metabolite enhances autophagy and controls Mycobacterium tuberculosis infection.Nat Commun2022
35102305Mycobacterium tuberculosis remodels host transcriptome.Nat Microbiol2022
35314194Mycobacterium tuberculosis encodes a YhhN family membrane protein with lysoplasmalogenase activity that protects against toxic host lysolipids.J Biol Chem2022
35217788Author Correction: Mycobacterium tuberculosis remodels host transcriptome.Nat Microbiol2022
35115549Myeloid cell interferon responses correlate with clearance of SARS-CoV-2.Nat Commun2022
32943400Phagosome-regulated mTOR signalling during sarcoidosis granuloma biogenesis.Eur Respir J2021
33674719IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection.Commun Biol2021
34903057Myeloid-Derived Suppressor Cells Mediate T Cell Dysfunction in Nonhuman Primate TB Granulomas.mBio2021
34380059Live and let die: TB control by enhancing apoptosis.Immunity2021
34580670Host- and age-dependent transcriptional changes in <i>Mycobacterium tuberculosis</i> cell envelope biosynthesis genes after exposure to human alveolar lining fluid.bioRxiv2021
34693385Tuberculosis endotypes to guide stratified host-directed therapy.Med2021
34389503Interferon gamma release assays for detection of latent Mycobacterium tuberculosis in older Hispanic people.Int J Infect Dis2021
34324578A prospective cross-sectional study of tuberculosis in elderly Hispanics reveals that BCG vaccination at birth is protective whereas diabetes is not a risk factor.PLoS One2021
34232086Acute Inflammation Confers Enhanced Protection against Mycobacterium tuberculosis Infection in Mice.Microbiol Spectr2021
34282414Myeloid cell interferon responses correlate with clearance of SARS-CoV-2.Res Sq2021
34163486Reversing Post-Infectious Epigenetic-Mediated Immune Suppression.Front Immunol2021
33462437Author Correction: Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets.Nat Microbiol2021
33340034Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets.Nat Microbiol2021
33107629Cy3-tilmanocept labeling of macrophages in joints of mice with antibody-induced arthritis and synovium of human patients with rheumatoid arthritis.J Orthop Res2021
31462144Induction of autophagy through CLEC4E in combination with TLR4: an innovative strategy to restrict the survival of <i>Mycobacterium tuberculosis</i>.Autophagy2020
33257679Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice.Nat Commun2020
33240287GPR183 Regulates Interferons, Autophagy, and Bacterial Growth During <i>Mycobacterium tuberculosis</i> Infection and Is Associated With TB Disease Severity.Front Immunol2020
32793903IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection.bioRxiv2020
32849608Current Sarcoidosis Models and the Importance of Focusing on the Granuloma.Front Immunol2020
32669568Ornithine-A urea cycle metabolite enhances autophagy and controls Mycobacterium tuberculosis infection.Nat Commun2020
32322562Challenges of Immune Response Diversity in the Human Population Concerning New Tuberculosis Diagnostics, Therapies, and Vaccines.Front Cell Infect Microbiol2020
30366849AR-13 reduces antibiotic-resistant bacterial burden in cystic fibrosis phagocytes and improves cystic fibrosis transmembrane conductance regulator function.J Cyst Fibros2019
30134122IL-13-regulated Macrophage Polarization during Granuloma Formation in an In Vitro Human Sarcoidosis Model.Am J Respir Cell Mol Biol2019
31511357Identification of an Increased Alveolar Macrophage Subpopulation in Old Mice That Displays Unique Inflammatory Characteristics and Is Permissive to <i>Mycobacterium tuberculosis</i> Infection.J Immunol2019
31478909Targeting innate immunity for tuberculosis vaccination.J Clin Invest2019
30897154Macrophage nuclear receptors: Emerging key players in infectious diseases.PLoS Pathog2019
30923818The Lung Mucosa Environment in the Elderly Increases Host Susceptibility to Mycobacterium tuberculosis Infection.J Infect Dis2019
30710047l-Arginine Synthesis from l-Citrulline in Myeloid Cells Drives Host Defense against Mycobacteria In Vivo.J Immunol2019
31060958Mycobacterium tuberculosis and macrophage nuclear receptors: What we do and don't know.Tuberculosis (Edinb)2019
30929010In Vitro Granuloma Models of Tuberculosis: Potential and Challenges.J Infect Dis2019
28853442PO and ID BCG vaccination in humans induce distinct mucosal and systemic immune responses and CD4<sup>+</sup> T cell transcriptomal molecular signatures.Mucosal Immunol2018
30029904Deletion of PPARγ in lung macrophages provides an immunoprotective response against M. tuberculosis infection in mice.Tuberculosis (Edinb)2018
29928066PPARγ is critical for Mycobacterium tuberculosis induction of Mcl-1 and limitation of human macrophage apoptosis.PLoS Pathog2018
29847580AmpliSeq transcriptome analysis of human alveolar and monocyte-derived macrophages over time in response to Mycobacterium tuberculosis infection.PLoS One2018
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Collaborators

Eusondia Arnett
Texas Biomedical Research Institute
Co-authored papers 16
Wolfgang Sad??e
College of Medicine, The Ohio State University
Co-authored papers 9
Mark D Wewers
The Ohio State University College of Medicine
Co-authored papers 7
Mikhail A Gavrilin
The Ohio State University, Wexner Medical Center
Co-authored papers 6
Nizar N Jarjour
Co-authored papers 5
Luis Martinez-Sobrido
Texas Biomedical Research Institute
Co-authored papers 5
Peter White
The Ohio State University
Co-authored papers 4
Chengjin Ye
Texas Biomedical Research Institute
Co-authored papers 3
Daniel J Wozniak
Co-authored papers 3
Hardy Kornfeld
University of Massachusetts Chan Medical School
Co-authored papers 3
Clay B Marsh
West Virginia University School of Medicine
Co-authored papers 3
Judy Day
University of Tennessee
Co-authored papers 3
Maxim N Artyomov
Co-authored papers 2
Patrice A Frost
Southwest National Primate Research Center
Co-authored papers 2
Huy Nguyen
The University of Danang-University of Science and Technology
Co-authored papers 2
Susan T Weintraub
University of Texas Health Science Center at San Antonio Texas78229 USA.
Co-authored papers 2
Ekaterina Esaulova
Co-authored papers 2
Spencer C Behr
University of California san francisco
Co-authored papers 2
Richard Copin
Regeneron Pharmaceuticals
Co-authored papers 2
David M Lewinsohn
Oregon Health and Science University
Co-authored papers 2
Gabriel I Small
Washington University School of Medicine
Co-authored papers 1
Ann N Reyes
Texas Biomedical Research Institute
Co-authored papers 1
James Fitch
The Institute for Genomic Medicine, Nationwide Children's Hospital
Co-authored papers 1
Alessandro Sette
Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology
Co-authored papers 1
Priya Luthra
Trudeau Institute
Co-authored papers 1
Robyn M Kaake
J. David Gladstone Institutes
Co-authored papers 1
Ramnik J Xavier
Broad Institute of MIT and Harvard
Co-authored papers 1
Brad R Rosenberg
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Christopher F Basler
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Michael K Mansour
Co-authored papers 1
Release 1.2