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Author Details

Joan M Robbins
DNATrix Inc.
1997
24
18
PMIDPaper TitleJournal TitlePublished Year
37188783Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial.Nat Med2023
29322091A Retroviral Replicating Vector Encoding Cytosine Deaminase and 5-FC Induces Immune Memory in Metastatic Colorectal Cancer Models.Mol Ther Oncolytics2017
28387849Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model.Neuro Oncol2017
28387831Retroviral replicating vector-mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity.Neuro Oncol2017
26918465Extensive Replication of a Retroviral Replicating Vector Can Expand the A Bulge in the Encephalomyocarditis Virus Internal Ribosome Entry Site and Change Translation Efficiency of the Downstream Transgene.Hum Gene Ther Methods2016
27166379Toca 511 plus 5-fluorocytosine in combination with lomustine shows chemotoxic and immunotherapeutic activity with no additive toxicity in rodent glioblastoma models.Neuro Oncol2016
27252174Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma.Sci Transl Med2016
25419577Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model.Hum Gene Ther2015
25301172Radiosensitization of gliomas by intracellular generation of 5-fluorouracil potentiates prodrug activator gene therapy with a retroviral replicating vector.Cancer Gene Ther2014
26015967Maintaining therapeutic activity in the operating room: compatibility of a gamma-retroviral replicating vector with clinical materials and biofluids.Mol Ther Methods Clin Dev2014
23703472Convection-enhanced delivery improves distribution and efficacy of tumor-selective retroviral replicating vectors in a rodent brain tumor model.Cancer Gene Ther2013
23969884Toca 511 gene transfer and 5-fluorocytosine in combination with temozolomide demonstrates synergistic therapeutic efficacy in a temozolomide-sensitive glioblastoma model.Cancer Gene Ther2013
22070930Brain tumor eradication and prolonged survival from intratumoral conversion of 5-fluorocytosine to 5-fluorouracil using a nonlytic retroviral replicating vector.Neuro Oncol2012
22365776Retroviral replicating vectors in cancer.Methods Enzymol2012
17026795Phase III multicenter randomized clinical trial to evaluate the safety and efficacy of CoFactor/5-fluorouracil/bevacizumab versus leucovorin/5-fluorouracil/bevacizumab as initial treatment for metastatic colorectal carcinoma.Clin Colorectal Cancer2006
16467915Catalytic nucleic acid enzymes for the study and development of therapies in the central nervous system: Review Article.Gene Ther Mol Biol2005
14511464Human alloreactive CTL interactions with gliomas and with those having upregulated HLA expression from exogenous IFN-gamma or IFN-gamma gene modification.J Interferon Cytokine Res2003
12356843Ribozyme to proliferating cell nuclear antigen to treat proliferative vitreoretinopathy.Invest Ophthalmol Vis Sci2002
11136250Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach.Proc Natl Acad Sci U S A2001
10871412A novel functional genomics approach identifies mTERT as a suppressor of fibroblast transformation.Nucleic Acids Res2000
10419050Phase I trial of interferon-gamma (IFN-gamma) retroviral vector administered intratumorally to patients with metastatic melanoma.Cancer Gene Ther1999
9794207Generation of a systemic antitumor response with regional intratumoral injections of interferon gamma retroviral vector.Hum Gene Ther1998
9581840DNA vaccines encoding full-length or truncated Neu induce protective immunity against Neu-expressing mammary tumors.Cancer Res1998
9080121Purified herpes simplex thymidine kinase Retrovector particles. I. In vitro characterization, in situ transduction efficiency, and histopathological analyses of gene therapy-treated brain tumors.Cancer Gene Ther1997
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Collaborators

Michael A Vogelbaum
Moffit Cancer Center
Co-authored papers 2
Timothy F Cloughesy
David Geffen School of Medicine, University of California Los Angeles
Co-authored papers 2
Clark C Chen
University of Minnesota
Co-authored papers 2
Takafumi N Yamaguchi
University of California los angeles
Co-authored papers 1
Roger Stupp
Northwestern University
Co-authored papers 1
Rachel M A Dang
University of California Los Angeles
Co-authored papers 1
Thomas J Kipps
University of California San Diego
Co-authored papers 1
Rohan Ramakrishna
Weill Cornell Medical College, New York Presbyterian Hospital
Co-authored papers 1
Adam M Sonabend
Northwestern University
Co-authored papers 1
Andrew Gao
University Health Network
Co-authored papers 1
Manish K Aghi
University of California san francisco
Co-authored papers 1
??lvaro L??pez-Janeiro
Clinica Universidad de Navarra
Co-authored papers 1
Tom Mikkelsen
Ontario Brain Institute
Co-authored papers 1
Suresh Nair
Lehigh Valley Topper Cancer Institute
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University of Washington
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The University of Texas MD Anderson Cancer Center
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National Cancer Institute
Co-authored papers 1
David M Peereboom
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Co-authored papers 1
Analiz Rodriguez
University of Arkansas for Medical Sciences
Co-authored papers 1
Robert Aiken
Rutgers Cancer Institute of New Jersey, Rutgers University
Co-authored papers 1
Bob S Carter
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 1
Jeff Liu
Princess Margaret Cancer Centre, University Health Network and University of Toronto
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Howard Colman
Huntsman Cancer Institute, University of Utah
Co-authored papers 1
Priya Kumthekar
Northwestern University, Feinberg School of Medicine
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Jason M Melear
Baylor University Medical Center
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Mariza Daras
University of California san francisco
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Frederick F Lang
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