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Author Details

Jun Lu
Yale University
2005
36
31
PMIDPaper TitleJournal TitlePublished Year
35081358Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2.Cell Rep2022
36292918CD44V3, an Alternatively Spliced Form of CD44, Promotes Pancreatic Cancer Progression.Int J Mol Sci2022
31874105The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas.J Clin Invest2020
29633759Publisher Correction: miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia.Nat Commun2018
28926530Erratum: The microRNA miR-31 inhibits CD8<sup>+</sup> T cell function in chronic viral infection.Nat Immunol2017
28530712The microRNA miR-31 inhibits CD8<sup>+</sup> T cell function in chronic viral infection.Nat Immunol2017
27041566Increased miR-155-5p and reduced miR-148a-3p contribute to the suppression of osteosarcoma cell death.Oncogene2016
27373493Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis.Exp Hematol2016
27070706miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.Cancer Cell2016
26832662miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.Cancer Cell2016
25256711A functional screen identifies miRs that induce radioresistance in glioblastomas.Mol Cancer Res2014
23340433MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11.Nat Commun2013
24298054The IGF2 intronic miR-483 selectively enhances transcription from IGF2 fetal promoters and enhances tumorigenesis.Genes Dev2013
22353710miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia.Nat Commun2012
23079661Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.Cancer Cell2012
21483750Genome-wide expression profiling of five mouse models identifies similarities and differences with human psoriasis.PLoS One2011
21408091MicroRNA expression profiling identifies activated B cell status in chronic lymphocytic leukemia cells.PLoS One2011
20133587Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia.Proc Natl Acad Sci U S A2010
20550935Lineage-specific transcriptional regulation of DICER by MITF in melanocytes.Cell2010
20616003MicroRNA miR-125a controls hematopoietic stem cell number.Proc Natl Acad Sci U S A2010
19060901ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling.Nat Immunol2009
19903759Dicer1 functions as a haploinsufficient tumor suppressor.Genes Dev2009
19582159microRNA expression during trophectoderm specification.PLoS One2009
19759263MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer.Genes Dev2009
19483683Lin28 promotes transformation and is associated with advanced human malignancies.Nat Genet2009
19188669Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization.Blood2009
19188439MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes.Mol Cell Biol2009
18238902Dicer-dependent pathways regulate chondrocyte proliferation and differentiation.Proc Natl Acad Sci U S A2008
18832181Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.Proc Natl Acad Sci U S A2008
19011087Human multipotent stromal cells from bone marrow and microRNA: regulation of differentiation and leukemia inhibitory factor expression.Proc Natl Acad Sci U S A2008
18539114MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors.Dev Cell2008
17401365Impaired microRNA processing enhances cellular transformation and tumorigenesis.Nat Genet2007
18056805MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia.Proc Natl Acad Sci U S A2007
17712037Altered microRNA expression in human heart disease.Physiol Genomics2007
15735639Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals.Nature2005
15944708MicroRNA expression profiles classify human cancers.Nature2005
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Collaborators

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Houston Methodist Hospital
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National Human Genome Research Institute
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McGill University
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University of Toronto
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Boston Children's Hospital, Seoul National University, Seoul National University Hospital
Co-authored papers 2
Tokyo Medical and Dental University Hospital
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Boston Children's Hospital, Harvard Medical School
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Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School
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Vita-Salute San Raffaele University
Co-authored papers 2
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Boston Children's Hospital, Harvard Medical School
Co-authored papers 2
University of Toronto
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
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Princess Margaret Cancer Centre, University Health Network
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Beth Israel Deaconess Medical Center
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Dana-Farber Cancer Institute
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Leeds Institute of Medical Research, University of Leeds
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Moores Cancer Center, University of California San Diego
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Broad Institute of the Massachusetts Institute of Technology and Harvard
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