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Author Details

Brent R Stockwell
Columbia University
1998
180
76
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36864031Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism.Nat Commun2023
37643353Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models.J Nat Prod2023
37550363The therapeutic potential of targeting regulated non-apoptotic cell death.Nat Rev Drug Discov2023
37468756Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP).Nat Cell Biol2023
37468619Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging.Nat Methods2023
37467745Regulation of VKORC1L1 is critical for p53-mediated tumor suppression through vitamin K metabolism.Cell Metab2023
37267948Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones.Cell2023
36747055Identification of essential sites of lipid peroxidation in ferroptosis.Nat Chem Biol2023
36865302A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma.bioRxiv2023
36864031Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism.Nat Commun2023
37364817Red blood cell exposure increases chondrocyte susceptibility to oxidative stress following hemarthrosis.Osteoarthritis Cartilage2023
36921996ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntington's disease.Genes Dev2023
37100955Apoptotic cell death in disease-Current understanding of the NCCD 2023.Cell Death Differ2023
36724221NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8.Sci Adv2023
37550363The therapeutic potential of targeting regulated non-apoptotic cell death.Nat Rev Drug Discov2023
37643353Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models.J Nat Prod2023
37468756Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP).Nat Cell Biol2023
37468619Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging.Nat Methods2023
37467745Regulation of VKORC1L1 is critical for p53-mediated tumor suppression through vitamin K metabolism.Cell Metab2023
37100955Apoptotic cell death in disease-Current understanding of the NCCD 2023.Cell Death Differ2023
37364817Red blood cell exposure increases chondrocyte susceptibility to oxidative stress following hemarthrosis.Osteoarthritis Cartilage2023
37267948Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones.Cell2023
36724221NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8.Sci Adv2023
36921996ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntington's disease.Genes Dev2023
36747055Identification of essential sites of lipid peroxidation in ferroptosis.Nat Chem Biol2023
36865302A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma.bioRxiv2023
35230809Machine Learning Classifies Ferroptosis and Apoptosis Cell Death Modalities with TfR1 Immunostaining.ACS Chem Biol2022
35393402Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19.Nat Commun2022
35803244Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications.Cell2022
36270246Vitamin K: A new guardian against ferroptosis.Mol Cell2022
35413274Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection.Cell Metab2022
35984649Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia.Cancer Discov2022
35352032The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis.Cell Res2022
36423641Small-molecule allosteric inhibitors of GPX4.Cell Chem Biol2022
35230809Machine Learning Classifies Ferroptosis and Apoptosis Cell Death Modalities with TfR1 Immunostaining.ACS Chem Biol2022
35213158Discovery of Anticancer Agents of Diverse Natural Origin.J Nat Prod2022
34931062Characterization of a patient-derived variant of GPX4 for precision therapy.Nat Chem Biol2022
35352032The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis.Cell Res2022
35803244Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications.Cell2022
35393402Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19.Nat Commun2022
35413274Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection.Cell Metab2022
36423641Small-molecule allosteric inhibitors of GPX4.Cell Chem Biol2022
36270246Vitamin K: A new guardian against ferroptosis.Mol Cell2022
35984649Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia.Cancer Discov2022
35213158Discovery of Anticancer Agents of Diverse Natural Origin.J Nat Prod2022
34931062Characterization of a patient-derived variant of GPX4 for precision therapy.Nat Chem Biol2022
33126055Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis.Redox Biol2021
34129825Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations.Cancer Cell2021
33910954Inhibitors of Coronavirus 3CL Proteases Protect Cells from Protease-Mediated Cytotoxicity.J Virol2021
33795671Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors.Nat Commun2021
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Collaborators

Stuart L Schreiber
Broad Institute
Co-authored papers 9
Donald C Lo
National Center for Advancing Translational Sciences
Co-authored papers 8
David E Root
Broad Institute of Harvard and MIT
Co-authored papers 8
Brian P Kelley
Novartis Institutes for BioMedical Research Inc.
Co-authored papers 7
Valerian E Kagan
Center for Free Radical and Antioxidant Health, University of Pittsburgh
Co-authored papers 6
Andrea Califano
Columbia University
Co-authored papers 5
Carlos L??pez-Ot??n
Instituto Universitario de Oncologia, Universidad de Oviedo
Co-authored papers 4
Ted M Dawson
Johns Hopkins University School of Medicine
Co-authored papers 4
Presha Rajbhandari
Columbia University
Co-authored papers 4
Valina L Dawson
Institute for Cell Engineering, Johns Hopkins University School of Medicine
Co-authored papers 4
Simone Fulda
Co-authored papers 4
Alykhan F Shamji
Center for the Science of Therapeutics, Broad Institute
Co-authored papers 4
William C Hahn
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Co-authored papers 4
Jan Paul Medema
Oncode Institute
Co-authored papers 4
Paul A Clemons
Broad Institute
Co-authored papers 4
David M Sabatini
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 3
Raul Rabadan
Columbia University Vagelos College of Physicians and Surgeons
Co-authored papers 3
Evripidis Gavathiotis
Albert Einstein College of Medicine
Co-authored papers 3
Jerry E Chipuk
Co-authored papers 3
Rosario Rizzuto
Co-authored papers 3
Joseph Lehár
Co-authored papers 3
Rajesh K Soni
Herbert Irving Comprehensive Cancer Center, Columbia University
Co-authored papers 3
Brian D Dynlacht
New York University Cancer Institute, New York University School of Medicine
Co-authored papers 3
Nicola Di Daniele
University of Rome Tor Vergata
Co-authored papers 3
Ekihiro Seki
Co-authored papers 3
Stuart A Lipton
The Scripps Research Institute, University of California
Co-authored papers 3
Fiona Ginty
GE Global Research Center
Co-authored papers 2
Tom Mikkelsen
Ontario Brain Institute
Co-authored papers 2
Joshua A Bittker
Co-authored papers 2
Garry P Nolan
Stanford University School of Medicine
Co-authored papers 2
Release 1.2