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Author Details
Full Name
Chad A Brautigam
Affiliation
UT Southwestern Medical Center
ORCID
Career Start Year
1997
Papers
143
H Index
46
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36890221
SViMULATE: a computer program facilitating interactive, multi-mode simulation of analytical ultracentrifugation data.
Eur Biophys J
2023
37585288
Hydrostatic Pressure Sensing by WNK kinases.
Mol Biol Cell
2023
37279758
A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders.
Structure
2023
37200262
Biophysical and biochemical studies support TP0094 as a phosphotransacetylase in an acetogenic energy-conservation pathway in Treponema pallidum.
PLoS One
2023
34796555
Inhibition of bacterial FMN transferase: A potential avenue for countering antimicrobial resistance.
Protein Sci
2022
35312285
A Protein Semisynthesis-Based Strategy to Investigate the Functional Impact of Linker Histone Serine ADP-Ribosylation.
ACS Chem Biol
2022
34652497
Correction to: Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study.
Eur Biophys J
2021
33881594
Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study.
Eur Biophys J
2021
33877597
Measuring the K<sub>D</sub> of Protein-Ligand Interactions Using Microscale Thermophoresis.
Methods Mol Biol
2021
33864101
A multi-laboratory benchmark study of isothermal titration calorimetry (ITC) using Ca<sup>2+</sup> and Mg<sup>2+</sup> binding to EDTA.
Eur Biophys J
2021
33689398
Osmosensing by WNK Kinases.
Mol Biol Cell
2021
33580145
Mechanism of karyopherin-β2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).
Sci Rep
2021
34506664
Modular Design of Supramolecular Ionic Peptides with Cell-Selective Membrane Activity.
Chembiochem
2021
32220963
Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.
Proc Natl Acad Sci U S A
2020
33659298
Molecular Size Analysis of Recombinant Importin-histone Complexes Using Analytical Ultracentrifugation.
Bio Protoc
2020
31829010
Fast and Robust Quantification of Detergent Micellization Thermodynamics from Isothermal Titration Calorimetry.
Anal Chem
2020
32963009
Biophysical and Biochemical Characterization of TP0037, a d-Lactate Dehydrogenase, Supports an Acetogenic Energy Conservation Pathway in Treponema pallidum.
mBio
2020
32761255
Using modern approaches to sedimentation velocity to detect conformational changes in proteins.
Eur Biophys J
2020
32698014
Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.
Cell Rep
2020
32520643
Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol Biol Cell
2020
30933465
Enhanced Sample Handling for Analytical Ultracentrifugation with 3D-Printed Centerpieces.
Anal Chem
2019
31535977
Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands.
Elife
2019
30855230
Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone.
Elife
2019
29318719
Crystal stuctures of MglB-2 (TP0684), a topologically variant d-glucose-binding protein from Treponema pallidum, reveal a ligand-induced conformational change.
Protein Sci
2018
30242931
Biophysical insights into a highly selective l-arginine-binding lipoprotein of a pathogenic treponeme.
Protein Sci
2018
29851564
An isolated CLASP TOG domain suppresses microtubule catastrophe and promotes rescue.
Mol Biol Cell
2018
29897335
Design principles of a microtubule polymerase.
Elife
2018
29411974
Fucosylated Molecules Competitively Interfere with Cholera Toxin Binding to Host Cells.
ACS Infect Dis
2018
29606581
RIM C<sub>2</sub>B Domains Target Presynaptic Active Zone Functions to PIP<sub>2</sub>-Containing Membranes.
Neuron
2018
29054528
Using two-site binding models to analyze microscale thermophoresis data.
Anal Biochem
2018
29196061
Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J Struct Biol
2018
28880148
Reconciling isothermal titration calorimetry analyses of interactions between complexin and truncated SNARE complexes.
Elife
2017
28168761
Functional clues from the crystal structure of an orphan periplasmic ligand-binding protein from Treponema pallidum.
Protein Sci
2017
28477408
Autoinhibition of Munc18-1 modulates synaptobrevin binding and helps to enable Munc13-dependent regulation of membrane fusion.
Elife
2017
29208896
Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing.
Nat Commun
2017
29127291
Structural basis of arrestin-3 activation and signaling.
Nat Commun
2017
28949297
Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites.
Elife
2017
29063833
SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
Elife
2017
28537552
Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex.
Elife
2017
26950369
Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors.
Nat Struct Mol Biol
2016
26626129
Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm.
Microbiologyopen
2016
27536942
The Tp0684 (MglB-2) Lipoprotein of Treponema pallidum: A Glucose-Binding Protein with Divergent Topology.
PLoS One
2016
26739938
On the acquisition and analysis of microscale thermophoresis data.
Anal Biochem
2016
26981768
The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores.
Elife
2016
27055097
Integration and global analysis of isothermal titration calorimetry data for studying macromolecular interactions.
Nat Protoc
2016
25312959
A Moraxella catarrhalis two-component signal transduction system necessary for growth in liquid media affects production of two lysozyme inhibitors.
Infect Immun
2015
26412649
Calculations and Publication-Quality Illustrations for Analytical Ultracentrifugation Data.
Methods Enzymol
2015
26627240
Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.
Proc Natl Acad Sci U S A
2015
26349033
Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife
2015
25877426
Identification of a core sequence for the binding of BosR to the rpoS promoter region in Borrelia burgdorferi.
Microbiology (Reading)
2015
1 - 50 of 143
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row(s) 1 - 30 of 30
Collaborators
Diana R Tomchick
University of Texas Southwestern Medical Center
Co-authored papers
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University of Texas Southwestern Medical Center
Co-authored papers
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Josep Rizo
University of Texas Southwestern Medical Center
Co-authored papers
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Michael K Rosen
UT Southwestern Medical Center
Co-authored papers
5
Luke M Rice
the University of Texas Southwestern Medical Center
Co-authored papers
4
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Co-authored papers
4
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2
Alexander K Buell
Institut fur Physikalische Biologie, Heinrich-Heine-Universitat Dusseldorf
Co-authored papers
2
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Co-authored papers
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Co-authored papers
2
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CUNY Advanced Science Research Center
Co-authored papers
2
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Jenny Jiou
University of Texas Southwestern Medical Center
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University of California San Francisco
Co-authored papers
1
Yu-Ju Chen
Institute of Chemistry
Co-authored papers
1
Geoffrey Neale
St. Jude Children's Research Hospital
Co-authored papers
1
Jordan M Baumhardt
University of Texas Southwestern Medical Center
Co-authored papers
1
Xue Zhong
Co-authored papers
1
Bing Li
Co-authored papers
1
Mark A Williams
Harwell Science & Innovation Campus
Co-authored papers
1
Takuya Yoshizawa
College of Life Sciences, Ritsumeikan University
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1
Prithwijit Sarkar
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1
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