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Author Details

Jeffrey H Kordower
ASU-Banner Neurodegenerative Disease Research Center, Arizona State University
1981
362
93
PMIDPaper TitleJournal TitlePublished Year
38006313Nigrostriatal tau pathology in parkinsonism and Parkinson's disease.Brain2024
35867714Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies.Autophagy2023
37634696Nigral-specific increase in ser31 phosphorylation compensates for tyrosine hydroxylase protein and nigrostriatal neuron loss: Implications for delaying parkinsonian signs.Exp Neurol2023
37662402Neither alpha-synuclein-preformed fibrils derived from patients with <i>GBA1</i> mutations nor the host murine genotype significantly influence seeding efficacy in the mouse olfactory bulb.bioRxiv2023
37544016Post-Mortem Studies of Neurturin Gene Therapy for Parkinson's Disease: Two Subjects with 10â¿¿Years CERE120 Delivery.Mov Disord2023
36966145Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis.NPJ Parkinsons Dis2023
36796948Mixed pathology as a rule, not exception: Time to reconsider disease nosology.Handb Clin Neurol2023
35103395Developing a pathway to support the appropriate, affordable, and widespread use of effective Alzheimer's prevention drugs.Alzheimers Dement2022
35634812The Unbearable Lightness of Brundin.J Parkinsons Dis2022
35449132Optimizing maturity and dose of iPSC-derived dopamine progenitor cell therapy for Parkinson's disease.NPJ Regen Med2022
33753910Enhanced CNS transduction from AAV.PHP.eB infusion into the cisterna magna of older adult rats compared to AAV9.Gene Ther2022
35082147In situ proximity labeling identifies Lewy pathology molecular interactions in the human brain.Proc Natl Acad Sci U S A2022
33009855Inflammation in Experimental Models of α-Synucleinopathies.Mov Disord2021
33684514GDNF signaling in subjects with minimal motor deficits and Parkinson's disease.Neurobiol Dis2021
33734581A novel tau-based rhesus monkey model of Alzheimer's pathogenesis.Alzheimers Dement2021
33749915Reply to: "Cell Therapy for Huntington's Disease: Learning from Failure".Mov Disord2021
34852293Corrigendum to "Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys" [EBioMedicine 2020; 59:102944].EBioMedicine2021
34766102SeqStain is an efficient method for multiplexed, spatialomic profiling of human and murine tissues.Cell Rep Methods2021
34613484A historical review of multiple system atrophy with a critical appraisal of cellular and animal models.J Neural Transm (Vienna)2021
33221532Viral-based rodent and nonhuman primate models of multiple system atrophy: Fidelity to the human disease.Neurobiol Dis2021
32997443Mitomycin-C treatment during differentiation of induced pluripotent stem cell-derived dopamine neurons reduces proliferation without compromising survival or function inâ¿¿vivo.Stem Cells Transl Med2021
30579705Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease.Neurobiol Dis2020
31993745T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease.Acta Neuropathol2020
31958098Does Developmental Variability in the Number of Midbrain Dopamine Neurons Affect Individual Risk for Sporadic Parkinson's Disease?J Parkinsons Dis2020
31714896Human autologous iPSC-derived dopaminergic progenitors restore motor function in Parkinson's disease models.J Clin Invest2020
32102975Disease modification and biomarker development in Parkinson disease: Revision or reconstruction?Neurology2020
33463751Reply to: "Toward a Personalized Approach to Parkinson's Cell Therapy".Mov Disord2020
32780511A Failed Future.Mov Disord2020
32810825Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys.EBioMedicine2020
32529662Stem Cells: Scientific and Ethical Quandaries of a Personalized Approach to Parkinson's Disease.Mov Disord2020
32508331GDNF and Parkinson's Disease: Where Next? A Summary from a Recent Workshop.J Parkinsons Dis2020
32238479Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease.J Neurosci2020
32203581Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease.Brain2020
32567651Corrigendum to: In Utero Exposure to Anesthetics Alters Neuronal Migration Pattern in Developing Cerebral Cortex and Causes Postnatal Behavioral Deficits in Rats.Cereb Cortex2020
30554160Role of TLR4 in the gut-brain axis in Parkinson's disease: a translational study from men to mice.Gut2019
31728405Endogenous alpha-synuclein monomers, oligomers and resulting pathology: let's talk about the lipids in the room.NPJ Parkinsons Dis2019
31580415Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes.Brain2019
31454546Immunotherapy in Parkinson's disease: Current status and future directions.Neurobiol Dis2019
31043478Low-Dose Maraviroc, an Antiretroviral Drug, Attenuates the Infiltration of T Cells into the Central Nervous System and Protects the Nigrostriatum in Hemiparkinsonian Monkeys.J Immunol2019
30984255Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity.Neural Plast2019
31152606Spreading of alpha-synuclein - relevant or epiphenomenon?J Neurochem2019
31056668Temporal evolution of microglia and α-synuclein accumulation following foetal grafting in Parkinson's disease.Brain2019
30908781Parkinson's disease gene therapy: Will focused ultrasound and nanovectors be the next frontier?Mov Disord2019
30788585Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms.Acta Neuropathol2019
31136023Focused ultrasound opening of the blood-brain barrier for treatment of Parkinson's disease.Mov Disord2019
30932894Loss of One Engrailed1 Allele Enhances Induced α-Synucleinopathy.J Parkinsons Dis2019
29341898Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology.Neurobiol Dis2018
30155513Proteasome-targeted nanobodies alleviate pathology and functional decline in an α-synuclein-based Parkinson's disease model.NPJ Parkinsons Dis2018
29856034Disease Modification Through Trophic Factor Delivery.Methods Mol Biol2018
28434076α-Synuclein nonhuman primate models of Parkinson's disease.J Neural Transm (Vienna)2018
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Collaborators

David A Bennett
Rush University Medical Center
Co-authored papers 7
Allan I Levey
Emory University School of Medicine
Co-authored papers 5
David G Standaert
University of Alabama at Birmingham
Co-authored papers 3
Ronald J Mandel
University of Florida College of Medicine
Co-authored papers 3
Clive N Svendsen
Co-authored papers 3
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Duke University Medical Center
Co-authored papers 3
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Co-authored papers 3
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John Van Geest Center for Brain Repair, University of Cambridge
Co-authored papers 2
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Uniformed Services University School of Medicine
Co-authored papers 2
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University of California
Co-authored papers 2
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Co-authored papers 2
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Inc. University Avenue
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National Institute on Aging
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Leslie M Thompson
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In-Hee Lee
Co-authored papers 1
Caroline M Tanner
UCSF School of Medicine and San Francisco VA Health Care System
Co-authored papers 1
Pierre Leblanc
McLean Hospital and Program in Neuroscience, Harvard Medical School
Co-authored papers 1
Kwang-Soo Kim
McLean Hospital and Program in Neuroscience, Harvard Medical School
Co-authored papers 1
P Hemachandra Reddy
Texas Tech University Health Sciences Center
Co-authored papers 1
Adam S Fleisher
Banner Alzheimer's Institute, University of California
Co-authored papers 1
Young Cha
McLean Hospital, Harvard Medical School
Co-authored papers 1
Philippe L Bedard
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Bruce M Cohen
Harvard Medical School
Co-authored papers 1
Dhruv Sareen
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Release 1.2