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Author Details

Xin Cong
Jiangsu Simcere Pharmaceutical Co. Ltd.
2004
17
13
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
30926315Discovery of potent anti-inflammatory 4-(4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-yl) pyrimidin-2-amines for use as Janus kinase inhibitors.Bioorg Med Chem2019
27041503Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.Neuron2016
26390242Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.Nat Med2015
24951334Design, synthesis and evaluation of highly selective pyridone-based class II MET inhibitors.Bioorg Med Chem Lett2014
22676037Correction to Design of Bcl-2 and Bcl-xL Inhibitors with Subnanomolar Binding Affinities Based upon a New Scaffold.J Med Chem2012
22747598Structure-based design of potent Bcl-2/Bcl-xL inhibitors with strong in vivo antitumor activity.J Med Chem2012
22448988Design of Bcl-2 and Bcl-xL inhibitors with subnanomolar binding affinities based upon a new scaffold.J Med Chem2012
22511757Inhibition of lipid signaling enzyme diacylglycerol kinase epsilon attenuates mutant huntingtin toxicity.J Biol Chem2012
21685499Mass spectrometric identification of novel lysine acetylation sites in huntingtin.Mol Cell Proteomics2011
19617626Calpain-1 cleaves and activates caspase-7.J Biol Chem2009
16469502Structural relationships in small molecule interactions governing gas-phase enantioselectivity and zwitterionic formation.J Am Soc Mass Spectrom2006
16782707Huntingtin phosphorylation sites mapped by mass spectrometry. Modulation of cleavage and toxicity.J Biol Chem2006
16808528Ring-closing metathesis-based synthesis of (3R,4R,5S)-4-acetylamino-5-amino-3-hydroxy- cyclohex-1-ene-carboxylic acid ethyl ester: a functionalized cycloalkene skeleton of GS4104.J Org Chem2006
15694767Zwitterion formation in gas-phase cyclodextrin complexes.J Am Soc Mass Spectrom2005
15903335Chemoselective deprotection of cyclic N,O-aminals using catalytic bismuth(III) bromide in acetonitrile.J Org Chem2005
15469360OBOC small-molecule combinatorial library encoded by halogenated mass-tags.Org Lett2004
15287776RCM approaches toward the diastereoselective synthesis of vicinal trans-diaminocyclitols from L-serine.J Org Chem2004
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Collaborators

Lisa M Ellerby
Buck Institute for Research on Aging
Co-authored papers 6
Bradford W Gibson
The Buck Institute for Research on Aging
Co-authored papers 5
Birgit Schilling
Buck Institute for Research on Aging
Co-authored papers 4
Yungui Zhou
Gladstone Institutes
Co-authored papers 2
Tara E Tracy
Buck Institute for Research on Aging
Co-authored papers 2
Sang-Won Min
Gladstone Institutes
Co-authored papers 2
Sakura Minami
Dokkyo Medical University
Co-authored papers 2
Jason M Held
Co-authored papers 2
Peter Dongmin Sohn
Gladstone Institutes
Co-authored papers 2
Yaqiao Li
Harvard Medical School
Co-authored papers 2
Chao Wang
Gladstone Institutes
Co-authored papers 2
Li Gan
Helen and Robert Appel Alzheimer's Disease Research Institute
Co-authored papers 2
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Jason E Gestwicki
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 1
Kotaro Shirakawa
Graduate School of Medicine, Kyoto University
Co-authored papers 1
Eric Verdin
Buck Institute for Research on Aging
Co-authored papers 1
Xu Chen
Gladstone Institutes
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Eliezer Masliah
National Institute On Aging
Co-authored papers 1
Michael P Cusack
Co-authored papers 1
Juan Botas
Baylor College of Medicine
Co-authored papers 1
Mehrdad Shamloo
Stanford University School of Medicine
Co-authored papers 1
Erwin B Defensor
Stanford University
Co-authored papers 1
Sue-Ann Mok
University of Alberta
Co-authored papers 1
Release 1.2