Author details

Full Name

Ulrika Krus

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36656641	Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets.		2023
35666870	Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets.	Proceedings of the National Academy of Sciences of the United States of America	2022
35948367	Islet Gene View-a tool to facilitate islet research.	Life Sci Alliance	2022
35869052	A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic Î²-cells.	Nature Communications	2022
33402679	Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.	Nat Commun	2021
33558525	Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.	Nat Commun	2021
32999275	Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D.	Nat Commun	2020
30865891	Decreased Expression of Cilia Genes in Pancreatic Islets as a Risk Factor for Type 2 Diabetes in Mice and Humans.	Cell Reports	2019
31676859	Loss of ZnT8 function protects against diabetes by enhanced insulin secretion.	Nature Genetics	2019
30293775	Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents Î² Cell Death via ATG16L1 Interaction and Autophagy Regulation.		2019
29093273	Genetic determinants of circulating GIP and GLP-1 concentrations.	JCI insight	2017
28882899	Glucose-Induced Changes in Gene Expression in Human Pancreatic Islets: Causes or Consequences of Chronic Hyperglycemia.		2017
27566545	C4b-binding Protein Protects Î²-Cells from Islet Amyloid Polypeptide-induced Cytotoxicity.	Journal of Biological Chemistry	2016
26206285	Altered serotonin (5-HT) 1D and 2A receptor expression may contribute to defective insulin and glucagon secretion in human type 2 diabetes.	Peptides	2015
25201977	Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.	Proc Natl Acad Sci U S A	2014
24726385	The complement inhibitor CD59 regulates insulin secretion by modulating exocytotic events.		2014
23557703	Effects of common genetic variants associated with type 2 diabetes and glycemic traits on Î±- and Î²-cell function and insulin action in humans.		2013
23140642	Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.	Cell Metab	2012
22768844	A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.	Cell Metab	2012
21826115	Abnormal peripheral chemokine profile in Huntington's disease.	PLoS Currents	2011
20415663	Pyruvate dehydrogenase kinase 1 controls mitochondrial metabolism and insulin secretion in INS-1 832/13 clonal beta-cells.	Biochemical Journal	2010