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Author Details
Full Name
Andrew J Gentles
Affiliation
Stanford Center for Biomedical Informatics Research, Stanford University
ORCID
Career Start Year
1999
Papers
102
H Index
43
Expertise
CM4AI Collaborator
Emma Lundberg (CM4AI)
PMID
Paper Title
Journal Title
Published Year
35926108
Single-cell genomics in AML: extending the frontiers of AML research.
Blood
2023
37790561
AML/T cell interactomics uncover correlates of patient outcomes and the key role of ICAM1 in T cell killing of AML.
bioRxiv
2023
37978395
Loss of p53-DREAM-mediated repression of cell cycle genes as a driver of lymph node metastasis in head and neck cancer.
Genome Med
2023
37067534
Translatome analysis reveals microglia and astrocytes to be distinct regulators of inflammation in the hyperacute and acute phases after stroke.
Glia
2023
36879008
High-resolution alignment of single-cell and spatial transcriptomes with CytoSPACE.
Nat Biotechnol
2023
36541010
Single Cell Spatial Biology for Precision Cancer Medicine.
Pac Symp Biocomput
2023
36824949
Translatome analysis reveals microglia and astrocytes to be distinct regulators of inflammation in the hyperacute and acute phases after stroke.
bioRxiv
2023
36929073
Profiling Cellular Ecosystems at Single-Cell Resolution and at Scale with EcoTyper.
Methods Mol Biol
2023
35094088
NSD1 mutations deregulate transcription and DNA methylation of bivalent developmental genes in Sotos syndrome.
Hum Mol Genet
2022
35525247
Lymph node colonization induces tumor-immune tolerance to promote distant metastasis.
Cell
2022
35654951
Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA.
Nat Methods
2022
35864305
Peripheral blood DNA methylation profiles predict future development of B-cell Non-Hodgkin Lymphoma.
NPJ Precis Oncol
2022
33024996
Conditional expression of HGAL leads to the development of diffuse large B-cell lymphoma in mice.
Blood
2021
33795428
Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling.
Science
2021
33670534
Prognostic Gene Expression, Stemness and Immune Microenvironment in Pediatric Tumors.
Cancers (Basel)
2021
34903734
Clonal architecture predicts clinical outcomes and drug sensitivity in acute myeloid leukemia.
Nat Commun
2021
34469729
High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment.
Cell Rep
2021
34543391
HGAL inhibits lymphoma dissemination by interacting with multiple cytoskeletal proteins.
Blood Adv
2021
34597589
The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma.
Cancer Cell
2021
34597583
Atlas of clinically distinct cell states and ecosystems across human solid tumors.
Cell
2021
34244432
Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment.
Proc Natl Acad Sci U S A
2021
32402275
Maternal Anti-Dengue IgG Fucosylation Predicts Susceptibility to Dengue Disease in Infants.
Cell Rep
2020
31933479
<i>MYC</i> and <i>Twist1</i> cooperate to drive metastasis by eliciting crosstalk between cancer and innate immunity.
Elife
2020
32238925
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.
Nature
2020
32381040
A human lung tumor microenvironment interactome identifies clinically relevant cell-type cross-talk.
Genome Biol
2020
30398435
Quantification of Macrophages in High-Grade Gliomas by Using Ferumoxytol-enhanced MRI: A Pilot Study.
Radiology
2019
31741777
Prognostic profiling of the immune cell microenvironment in Ewing´s Sarcoma Family of Tumors.
Oncoimmunology
2019
31217338
Targetable genetic alterations of <i>TCF4</i> (<i>E2-2</i>) drive immunoglobulin expression in diffuse large B cell lymphoma.
Sci Transl Med
2019
31433971
The Immune Landscape of Cancer.
Immunity
2019
31515215
Perfusion MRI-Based Fractional Tumor Burden Differentiates between Tumor and Treatment Effect in Recurrent Glioblastomas and Informs Clinical Decision-Making.
AJNR Am J Neuroradiol
2019
31447348
LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL.
Cancer Cell
2019
31061481
Determining cell type abundance and expression from bulk tissues with digital cytometry.
Nat Biotechnol
2019
30728456
Data mining for mutation-specific targets in acute myeloid leukemia.
Leukemia
2019
28727543
Non-Small Cell Lung Cancer Radiogenomics Map Identifies Relationships between Molecular and Imaging Phenotypes with Prognostic Implications.
Radiology
2018
29545928
Brd4 regulates the expression of essential autophagy genes and Keap1 in AML cells.
Oncotarget
2018
29513759
Subtype assignment of CLL based on B-cell subset associated gene signatures from normal bone marrow - A proof of concept study.
PLoS One
2018
29625051
Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation.
Cell
2018
29760045
<i>GFPT2</i>-Expressing Cancer-Associated Fibroblasts Mediate Metabolic Reprogramming in Human Lung Adenocarcinoma.
Cancer Res
2018
29331675
Module Analysis Captures Pancancer Genetically and Epigenetically Deregulated Cancer Driver Genes for Smoking and Antiviral Response.
EBioMedicine
2018
27663899
Role of KEAP1/NRF2 and TP53 Mutations in Lung Squamous Cell Carcinoma Development and Radiation Resistance.
Cancer Discov
2017
28314692
Identification of an atypical etiological head and neck squamous carcinoma subtype featuring the CpG island methylator phenotype.
EBioMedicine
2017
28089908
Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.
Cell Stem Cell
2017
29100315
Low BUB1 expression is an adverse prognostic marker in gastric adenocarcinoma.
Oncotarget
2017
29213088
NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma.
Sci Rep
2017
28679399
Data normalization considerations for digital tumor dissection.
Genome Biol
2017
27145341
Identifying Network Perturbation in Cancer.
PLoS Comput Biol
2016
27151888
Pathophysiological significance and therapeutic targeting of germinal center kinase in diffuse large B-cell lymphoma.
Blood
2016
25398938
Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition.
Blood
2015
26387756
CD93 Marks a Non-Quiescent Human Leukemia Stem Cell Population and Is Required for Development of MLL-Rearranged Acute Myeloid Leukemia.
Cell Stem Cell
2015
26286589
Integrating Tumor and Stromal Gene Expression Signatures With Clinical Indices for Survival Stratification of Early-Stage Non-Small Cell Lung Cancer.
J Natl Cancer Inst
2015
1 - 50 of 102
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