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Author Details

Sevtap Savas
Memorial University
1999
65
18
PMIDPaper TitleJournal TitlePublished Year
36998434Multifactor dimensionality reduction method identifies novel SNP interactions in the WNT protein interaction networks that are associated with recurrence risk in colorectal cancer.Front Oncol2023
34996992Genome-wide association study identifies tumor anatomical site-specific risk variants for colorectal cancer survival.Sci Rep2022
36548287Cancer prevention in cancer predisposition syndromes: A protocol for testing the feasibility of building a hereditary cancer research registry and nurse navigator follow up model.PLoS One2022
35991579Examining SNP-SNP interactions and risk of clinical outcomes in colorectal cancer using multifactor dimensionality reduction based methods.Front Genet2022
36057599Public Interest Group on Cancer Research: a successful patient-researcher partnership in Newfoundland and Labrador.Res Involv Engagem2022
33462316GATA3 somatic mutations are associated with clinicopathological features and expression profile in TCGA breast cancer patients.Sci Rep2021
34309201A comprehensive analysis of SNPs and CNVs identifies novel markers associated with disease outcomes in colorectal cancer.Mol Oncol2021
31077174Correction to: A genome-wide association study identifies single nucleotide polymorphisms associated with time-to-metastasis in colorectal cancer.BMC Cancer2019
31352904The long-term survival characteristics of a cohort of colorectal cancer patients and baseline variables associated with survival outcomes with or without time-varying effects.BMC Med2019
30738427A genome-wide association study identifies single nucleotide polymorphisms associated with time-to-metastasis in colorectal cancer.BMC Cancer2019
29394274XRCC3 Thr241Met and TYMS variable number tandem repeat polymorphisms are associated with time-to-metastasis in colorectal cancer.PLoS One2018
29942513Associations of single nucleotide polymorphisms with mucinous colorectal cancer: genome-wide common variant and gene-based rare variant analyses.Biomark Res2018
29894502Two functional indel polymorphisms in the promoter region of the Brahma gene (BRM) and disease risk and progression-free survival in colorectal cancer.PLoS One2018
29409465Association of rs2282679 A>C polymorphism in vitamin D binding protein gene with colorectal cancer risk and survival: effect modification by dietary vitamin D intake.BMC Cancer2018
29482773The SWI/SNF complex subunit genes: Their functions, variations, and links to risk and survival outcomes in human cancers.Crit Rev Oncol Hematol2018
28074552Validation of microRNA pathway polymorphisms in esophageal adenocarcinoma survival.Cancer Med2017
28376164Germline Mutations in the Kallikrein 6 Region and Predisposition for Aggressive Prostate Cancer.J Natl Cancer Inst2017
28765616Vitamin D receptor and calcium-sensing receptor polymorphisms and colorectal cancer survival in the Newfoundland population.Br J Cancer2017
28544645Germline INDELs and CNVs in a cohort of colorectal cancer patients: their characteristics, associations with relapse-free survival time, and potential time-varying effects on the risk of relapse.Cancer Med2017
26816351ABCC2 polymorphisms and survival in the Princess Margaret cohort study and the NCIC clinical trials group BR.24 trial of platinum-treated advanced stage non-small cell lung cancer patients.Cancer Epidemiol2016
27334288No associations of a set of SNPs in the Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinase (MMP) genes with survival of colorectal cancer patients.Cancer Med2016
27127412Biomarkers For Colon Cancer.Biomark Cancer2016
26014353Discovery and validation of vascular endothelial growth factor (VEGF) pathway polymorphisms in esophageal adenocarcinoma outcome.Carcinogenesis2015
26116242Mitochondrial DNA polymorphisms, its copy number change and outcome in colorectal cancer.BMC Res Notes2015
26064972A Survival Association Study of 102 Polymorphisms Previously Associated with Survival Outcomes in Colorectal Cancer.Biomed Res Int2015
25866641A genome wide association study on Newfoundland colorectal cancer patients' survival outcomes.Biomark Res2015
24448365Influence of pre-diagnostic cigarette smoking on colorectal cancer survival: overall and by tumour molecular phenotype.Br J Cancer2014
25405996Examining the polymorphisms in the hypoxia pathway genes in relation to outcome in colorectal cancer.PLoS One2014
25342289Inferring gene network from candidate SNP association studies using a Bayesian graphical model: application to a breast cancer case-control study from ontario.Hum Hered2014
23396503Dietary patterns and colorectal cancer recurrence and survival: a cohort study.BMJ Open2013
23626689MTHFR Glu429Ala and ERCC5 His46His polymorphisms are associated with prognosis in colorectal cancer patients: analysis of two independent cohorts from Newfoundland.PLoS One2013
23704879Missense variants of uncertain significance (VUS) altering the phosphorylation patterns of BRCA1 and BRCA2.PLoS One2013
23773794Special considerations in prognostic research in cancer involving genetic polymorphisms.BMC Med2013
22150118A curated database of genetic markers from the angiogenesis/VEGF pathway and their relation to clinical outcome in human cancers.Acta Oncol2012
22733538Vascular endothelial growth factor pathway polymorphisms as prognostic and pharmacogenetic factors in cancer: a systematic review and meta-analysis.Clin Cancer Res2012
22911682Serotonin transporter gene (SLC6A4) variations are associated with poor survival in colorectal cancer patients.PLoS One2012
22076708Validation of genetic sequence variants as prognostic factors in early-stage head and neck squamous cell cancer survival.Clin Cancer Res2012
22009713Genetic sequence variants and the development of secondary primary cancers in patients with head and neck cancers.Cancer2012
21483694NCI60 cancer cell line panel data and RNAi analysis help identify EAF2 as a modulator of simvastatin and lovastatin response in HCT-116 cells.PLoS One2011
21314952Bioinformatic analyses identifies novel protein-coding pharmacogenomic markers associated with paclitaxel sensitivity in NCI60 cancer cell lines.BMC Med Genomics2011
20670087Useful genetic variation databases for oncologists investigating the genetic basis of variable treatment response and survival in cancer.Acta Oncol2010
20830292A whole-genome SNP association study of NCI60 cell line panel indicates a role of Ca2+ signaling in selenium resistance.PLoS One2010
20506273dbCPCO: a database of genetic markers tested for their predictive and prognostic value in colorectal cancer.Hum Mutat2010
19499547A comprehensive catalogue of functional genetic variations in the EGFR pathway: protein-protein interaction analysis reveals novel genes and polymorphisms important for cancer research.Int J Cancer2009
19581524Studying genetic variations in cancer prognosis (and risk): a primer for clinicians.Oncologist2009
19639655Genetic variations as cancer prognostic markers: review and update.Hum Mutat2009
17680692Biological implications of SNPs in signal peptide domains of human proteins.Proteins2008
18330920Discovery of genetic profiles impacting response to chemotherapy: application to gemcitabine.Hum Mutat2008
17190851Functional nonsynonymous single nucleotide polymorphisms from the TGF-beta protein interaction network.Physiol Genomics2007
17567920Polymorphisms cMyc-N11S and p27-V109G and breast cancer risk and prognosis.BMC Cancer2007
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Collaborators

Hilmi Ozcelik
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 18
Wei Xu
Princess Margaret Cancer Centre
Co-authored papers 11
Geoffrey Liu
The Princess Margaret Cancer Centre/University of Toronto
Co-authored papers 11
Abul Kalam Azad
University of Dhaka
Co-authored papers 6
Laurent Briollais
Institute of Health Policy, Dalla Lana School of Public Health, University of Toronto
Co-authored papers 6
Dangxiao Cheng
University Health Network
Co-authored papers 6
Jingxiong Xu
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 5
John R McLaughlin
University of Toronto Dalla Lana School of Public Health
Co-authored papers 5
Lawson Eng
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 4
Xin Qiu
SLR Consulting (Canada) Ltd
Co-authored papers 4
Bharati Bapat
Mt Sinai Hospital
Co-authored papers 3
Isabelle Bairati
Laval University Cancer Research Center
Co-authored papers 2
Holly Etchegary
Memorial University
Co-authored papers 2
Guangju Zhai
Co-authored papers 2
John Waldron
University of Toronto, Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Fran??ois Meyer
Laval University
Co-authored papers 2
David P Goldstein
Princess Margaret Cancer Centre/University Health Network, University of Toronto
Co-authored papers 2
Mark A Batzer
Louisiana State University
Co-authored papers 2
Gail Darling
University of Toronto
Co-authored papers 2
Lorin Dodbiba
McMaster University
Co-authored papers 2
Neil E Fleshner
University of Toronto
Co-authored papers 2
Maryam Mirshams
Princess Margaret Cancer Centre
Co-authored papers 2
John Trachtenberg
University of Toronto, University Health Network
Co-authored papers 1
Karen Chadwick
University Health Network, University of Toronto
Co-authored papers 1
Graham G Giles
Co-authored papers 1
H??lya Kayserili
Istanbul University
Co-authored papers 1
Diane Rushlow
Toronto Western Hospital
Co-authored papers 1
Zhuo Chen
The First Hospital of Lanzhou University
Co-authored papers 1
Cynthia Kuk
Mount Sinai Hospital, University of Toronto, University Health Network
Co-authored papers 1
Matt Friedlander
Ontario Institute for Cancer Research
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