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Author Details

Frances Lu
2010
8
8
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
29350927Synthesis and Pharmacological Characterization of C4<sub>β</sub>-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1 S,2 S,4 S,5 R,6 S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Highly Potent and Selective mGlu<sub>3</sub> Receptor Agonist.J Med Chem2018
29695780Structural basis for GPR40 allosteric agonism and incretin stimulation.Nat Commun2018
26996964Computationally Designed Bispecific Antibodies using Negative State Repertoires.Structure2016
25602126Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain structures.J Med Chem2015
26313429Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist.J Med Chem2015
19944699Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry.J Mol Biol2010
20150177Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.Protein Eng Des Sel2010
20737437Structure of a putative BenF-like porin from Pseudomonas fluorescens Pf-5 at 2.6 A resolution.Proteins2010
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