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Author Details
Full Name
Michael F Gurish
Affiliation
Brigham and Women's Hospital, Harvard Medical School
ORCID
Career Start Year
1981
Papers
106
H Index
55
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
32079724
CUX1 and IκBζ (NFKBIZ) mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts.
Proc Natl Acad Sci U S A
2020
30639224
Deficiency of mouse mast cell protease 4 mitigates cardiac dysfunctions in mice after myocardium infarction.
Biochim Biophys Acta Mol Basis Dis
2019
31849960
Cell Intrinsic Deregulated ÿ-Catenin Signaling Promotes Expansion of Bone Marrow Derived Connective Tissue Type Mast Cells, Systemic Inflammation, and Colon Cancer.
Front Immunol
2019
31456904
Mouse Mast Cell Protease-4 Recruits Leukocytes in the Inflammatory Phase of Surgically Wounded Skin.
Adv Wound Care (New Rochelle)
2019
31536480
PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21.
JCI Insight
2019
29429965
Mast cells promote small bowel cancer in a tumor stage-specific and cytokine-dependent manner.
Proc Natl Acad Sci U S A
2018
30333237
Mixed-effects association of single cells identifies an expanded effector CD4<sup>+</sup> T cell subset in rheumatoid arthritis.
Sci Transl Med
2018
29051149
Resolution of a human mast cell development conundrum.
Blood
2017
28375155
Megakaryocytes compensate for Kit insufficiency in murine arthritis.
J Clin Invest
2017
28150777
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis.
Nature
2017
25388245
Methods for the study of mast cell recruitment and accumulation in different tissues.
Methods Mol Biol
2015
25291985
Maturation of mast cell progenitors to mucosal mast cells during allergic pulmonary inflammation in mice.
Mucosal Immunol
2015
24412367
Critical role for mast cell Stat5 activity in skin inflammation.
Cell Rep
2014
25320274
Mouse mast cell protease-6 and MHC are involved in the development of experimental asthma.
J Immunol
2014
24982172
IL-33/ST2 axis promotes mast cell survival via BCLXL.
Proc Natl Acad Sci U S A
2014
24928991
B cells regulate CD4+ T cell responses to papain following B cell receptor-independent papain uptake.
J Immunol
2014
24507159
Development of mast cells and importance of their tryptase and chymase serine proteases in inflammation and wound healing.
Adv Immunol
2014
24523504
Mouse mast cell proteases 4 and 5 mediate epidermal injury through disruption of tight junctions.
J Immunol
2014
24319003
Granule maturation in mast cells: histamine in control.
Eur J Immunol
2014
23149659
Direct effects of IL-4 on mast cells drive their intestinal expansion and increase susceptibility to anaphylaxis in a murine model of food allergy.
Mucosal Immunol
2013
23596057
Pivotal role of mouse mast cell protease 4 in the conversion and pressor properties of Big-endothelin-1.
J Pharmacol Exp Ther
2013
23540619
Development of skin lesions in filaggrin-deficient mice is dependent on adaptive immunity.
J Allergy Clin Immunol
2013
23319739
Mast cells recruited to mesenteric lymph nodes during helminth infection remain hypogranular and produce IL-4 and IL-6.
J Immunol
2013
23374269
Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis.
J Allergy Clin Immunol
2013
22840841
Developmental origin and functional specialization of mast cell subsets.
Immunity
2012
21167580
IgE-mediated systemic anaphylaxis and impaired tolerance to food antigens in mice with enhanced IL-4 receptor signaling.
J Allergy Clin Immunol
2011
22094766
Mast cells are required in the proliferation and remodeling phases of microdeformational wound therapy.
Plast Reconstr Surg
2011
21825171
Protease phenotype of constitutive connective tissue and of induced mucosal mast cells in mice is regulated by the tissue.
Proc Natl Acad Sci U S A
2011
21713649
Mast cell progenitor trafficking and maturation.
Adv Exp Med Biol
2011
20427772
The role of the CCL2/CCR2 axis in mouse mast cell migration in vitro and in vivo.
J Immunol
2010
21076070
The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5.
J Immunol
2010
20601599
T regulatory cells control antigen-induced recruitment of mast cell progenitors to the lungs of C57BL/6 mice.
J Immunol
2010
20133688
NIP45 controls the magnitude of the type 2 T helper cell response.
Proc Natl Acad Sci U S A
2010
19201896
IgE influences the number and function of mature mast cells, but not progenitor recruitment in allergic pulmonary inflammation.
J Immunol
2009
20018751
Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism.
Proc Natl Acad Sci U S A
2009
19720934
Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation.
Circulation
2009
19783672
Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells.
J Immunol
2009
19570783
T-regulatory cells shift from a protective anti-inflammatory to a cancer-promoting proinflammatory phenotype in polyposis.
Cancer Res
2009
19109198
Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes.
J Immunol
2009
19299652
The expanding universe of the basophil.
Blood
2009
18354212
Mouse mast cell tryptase mMCP-6 is a critical link between adaptive and innate immunity in the chronic phase of Trichinella spiralis infection.
J Immunol
2008
18988802
Genetic inversion in mast cell-deficient (Wsh) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy.
Am J Pathol
2008
17498048
Pathways of murine mast cell development and trafficking: tracking the roots and routes of the mast cell.
Immunol Rev
2007
18077429
Mast cells are an essential hematopoietic component for polyp development.
Proc Natl Acad Sci U S A
2007
18077323
Pulmonary CXCR2 regulates VCAM-1 and antigen-induced recruitment of mast cell progenitors.
Proc Natl Acad Sci U S A
2007
17277081
Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1.
Proc Natl Acad Sci U S A
2007
17296784
Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue.
J Exp Med
2007
16670268
Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung.
Blood
2006
16750988
Mast cells: ontogeny, homing, and recruitment of a unique innate effector cell.
J Allergy Clin Immunol
2006
16947397
Lymphocyte-independent connective tissue mast cells populate murine synovium.
Arthritis Rheum
2006
1 - 50 of 106
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School of Biomedical Sciences and Pharmacy, University of Newcastle
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Harvard Medical School
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University of California San Francisco
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Johns Hopkins University School of Medicine
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Co-authored papers
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Harvard Medical School
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University of NSW
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Elizabeth W Karlson
Brigham and Women's Hospital
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Jonathan S Coblyn
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Jason L Hornick
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Stephen U Stechschulte
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