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Author Details

James A Wohlschlegel
David Geffen School of Medicine, University of California Los Angeles
1996
244
66
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38062165In vivo identification of astrocyte and neuron subproteomes by proximity-dependent biotinylation.Nat Protoc2024
36640336Neuronal and astrocytic contributions to Huntington's disease dissected with zinc finger protein transcriptional repressors.Cell Rep2023
37967186ACD15, ACD21, and SLN regulate the accumulation and mobility of MBD6 to silence genes and transposable elements.Sci Adv2023
37962355Adenovirus E1A binding to DCAF10 targets proteasomal degradation of RUVBL1/2 AAA+ ATPases required for quaternary assembly of multiprotein machines, innate immunity, and responses to metabolic stress.J Virol2023
37633952FAP106 is an interaction hub for assembling microtubule inner proteins at the cilium inner junction.Nat Commun2023
37662299ACD15, ACD21 and SLN regulate accumulation and mobility of MBD6 to silence genes and transposable elements.bioRxiv2023
37591242FBXL12 degrades FANCD2 to regulate replication recovery and promote cancer cell survival under conditions of replication stress.Mol Cell2023
37790489The apoptotic splicing regulators RBM5 and RBM10 are subunits of the U2 snRNP engaged with intron branch sites on chromatin.bioRxiv2023
37782662Identification of IMC43, a novel IMC protein that collaborates with IMC32 to form an essential daughter bud assembly complex in Toxoplasma gondii.PLoS Pathog2023
37503245PEXEL is a proteolytic maturation site for both exported and non-exported <i>Plasmodium</i> proteins.bioRxiv2023
37873314Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome.bioRxiv2023
37816063Unexpected metabolic rewiring of CO<sub>2</sub> fixation in H<sub>2</sub>-mediated materials-biology hybrids.Proc Natl Acad Sci U S A2023
37768053The <i>Toxoplasma gondii</i> effector GRA83 modulates the host's innate immune response to regulate parasite infection.mSphere2023
38089570Wild-type C-Raf gene dosage and dimerization drive prostate cancer metastasis.iScience2023
37046092Astrocyte-neuron subproteomes and obsessive-compulsive disorder mechanisms.Nature2023
36977663Arabidopsis TRB proteins function in H3K4me3 demethylation by recruiting JMJ14.Nat Commun2023
37039990Analyzing Iron and Oxygen-Regulated Protein Complex Formation Using Proteomic Mass Spectrometry.Methods Mol Biol2023
37438334The MOM1 complex recruits the RdDM machinery via MORC6 to establish de novo DNA methylation.Nat Commun2023
37101218MORC proteins regulate transcription factor binding by mediating chromatin compaction in active chromatin regions.Genome Biol2023
36971339Transcriptional drifts associated with environmental changes in endothelial cells.Elife2023
37398161The <i>Toxoplasma gondii</i> effector GRA83 modulates the host's innate immune response to regulate parasite infection.bioRxiv2023
37398144Chikungunya virus glycoproteins transform macrophages into productive viral dissemination vessels.bioRxiv2023
37398139<i>Toxoplasma gondii</i> encodes an array of TBC-domain containing proteins including an essential regulator that targets Rab2 in the secretory pathway.bioRxiv2023
37129369Role of cytoneme structures and extracellular vesicles in <i>Trichomonas vaginalis</i> parasite-parasite communication.Elife2023
37126705Direct tests of cytochrome <i>c</i> and <i>c</i><sub>1</sub> functions in the electron transport chain of malaria parasites.Proc Natl Acad Sci U S A2023
36622147IMC29 Plays an Important Role in <i>Toxoplasma</i> Endodyogeny and Reveals New Components of the Daughter-Enriched IMC Proteome.mBio2023
36477540CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization.Nature2023
36879017A gene silencing screen uncovers diverse tools for targeted gene repression in Arabidopsis.Nat Plants2023
36747727Direct Tests of Cytochrome Function in the Electron Transport Chain of Malaria Parasites.bioRxiv2023
36836934Proteomic Analysis of Ferrochelatase Interactome in Erythroid and Non-Erythroid Cells.Life (Basel)2023
36711532The MOM1 complex recruits the RdDM machinery via MORC6 to establish <i>de novo</i> DNA methylation.bioRxiv2023
35027454The role of ATXR6 expression in modulating genome stability and transposable element repression in <i>Arabidopsis</i>.Proc Natl Acad Sci U S A2022
35654137Iron-regulated assembly of the cytosolic iron-sulfur cluster biogenesis machinery.J Biol Chem2022
35504914Functional identification of microRNA-centered complexes in C. elegans.Sci Rep2022
35668117Comprehensive identification of SWI/SNF complex subunits underpins deep eukaryotic ancestry and reveals new plant components.Commun Biol2022
36373674The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.Elife2022
36067236Elucidation of TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes.PLoS Pathog2022
36379930Histone chaperone ASF1 mediates H3.3-H4 deposition in Arabidopsis.Nat Commun2022
36347042High-Field Asymmetric Waveform Ion Mobility Spectrometry Interface Enhances Parallel Reaction Monitoring on an Orbitrap Mass Spectrometer.Anal Chem2022
36189880The TRIPLE PHD FINGERS proteins are required for SWI/SNF complex-mediated +1 nucleosome positioning and transcription start site determination in Arabidopsis.Nucleic Acids Res2022
35946312A genetic model for <i>in vivo</i> proximity labelling of the mammalian secretome.Open Biol2022
35878026Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation.Proc Natl Acad Sci U S A2022
35313331Porcupine Inhibition Disrupts Mitochondrial Function and Homeostasis in WNT Ligand-Addicted Pancreatic Cancer.Mol Cancer Ther2022
35182481A FBXO7/EYA2-SCF[FBXW7] axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells.Mol Cell2022
34934014Members of the KCTD family are major regulators of cAMP signaling.Proc Natl Acad Sci U S A2022
33357448FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells.Cell2021
33568455APEX2 Proximity Proteomics Resolves Flagellum Subdomains and Identifies Flagellum Tip-Specific Proteins in Trypanosoma brucei.mSphere2021
33846325Regulation of Arabidopsis photoreceptor CRY2 by two distinct E3 ubiquitin ligases.Nat Commun2021
33758928microRNA-mediated translation repression through GYF-1 and IFE-4 in C. elegans development.Nucleic Acids Res2021
33705894RGS10 physically and functionally interacts with STIM2 and requires store-operated calcium entry to regulate pro-inflammatory gene expression in microglia.Cell Signal2021
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Collaborators

David Geffen School of Medicine, University of California los angeles
Co-authored papers 100
TheScripps Research Institute
Co-authored papers 24
Co-authored papers 12
University of California San Francisco
Co-authored papers 7
University of California los angeles
Co-authored papers 6
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Co-authored papers 6
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Co-authored papers 5
David Geffen School of Medicine, University of California los angeles
Co-authored papers 5
Co-authored papers 5
Memorial Sloan-Kettering Cancer Center
Co-authored papers 4
Co-authored papers 4
The Scripps Research Institute
Co-authored papers 4
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 4
Co-authored papers 4
Co-authored papers 3
Co-authored papers 3
Middlemore Hospital
Co-authored papers 3
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 3
The Scripps Research Institute
Co-authored papers 3
Loyola University Chicago
Co-authored papers 3
The Scripps Research Institute
Co-authored papers 2
University of California los angeles
Co-authored papers 2
Co-authored papers 2
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University of California los angeles
Co-authored papers 2
University of California irvine
Co-authored papers 2
University College London, UK UCL Cancer Institute
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UPMC Hillman Cancer Center, University of Pittsburgh Medical Center
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KTH Royal Institute of Technology
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University of California san francisco
Co-authored papers 2