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Author Details

Jami Willette-Brown
Center for Cancer Research, National Cancer Institute
1989
42
22
PMIDPaper TitleJournal TitlePublished Year
35121655IKKα-deficient lung adenocarcinomas generate an immunosuppressive microenvironment by overproducing Treg-inducing cytokines.Proc Natl Acad Sci U S A2022
36270982A TNFR1-UBCH10 axis drives lung squamous cell carcinoma dedifferentiation and metastasis through a cell-autonomous signaling loop.Cell Death Dis2022
35121655IKKα-deficient lung adenocarcinomas generate an immunosuppressive microenvironment by overproducing Treg-inducing cytokines.Proc Natl Acad Sci U S A2022
36270982A TNFR1-UBCH10 axis drives lung squamous cell carcinoma dedifferentiation and metastasis through a cell-autonomous signaling loop.Cell Death Dis2022
33188780NLRP3 Inhibition Ameliorates Severe Cutaneous Autoimmune Manifestations in a Mouse Model of Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy-Like Disease.J Invest Dermatol2021
34170918A phase 2 trial of the somatostatin analog pasireotide to prevent GI toxicity and acute GVHD in allogeneic hematopoietic stem cell transplant.PLoS One2021
33188780NLRP3 Inhibition Ameliorates Severe Cutaneous Autoimmune Manifestations in a Mouse Model of Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy-Like Disease.J Invest Dermatol2021
34170918A phase 2 trial of the somatostatin analog pasireotide to prevent GI toxicity and acute GVHD in allogeneic hematopoietic stem cell transplant.PLoS One2021
31462685Endogenous thrombopoietin levels are elevated following double cord blood unit transplantation.Bone Marrow Transplant2020
31616065A phase II study of reduced intensity double umbilical cord blood transplantation using fludarabine, melphalan, and low dose total body irradiation.Bone Marrow Transplant2020
33125970C-CBL is required for inhibition of angiogenesis through modulating JAK2/STAT3 activity in ROP development.Biomed Pharmacother2020
31462685Endogenous thrombopoietin levels are elevated following double cord blood unit transplantation.Bone Marrow Transplant2020
33125970C-CBL is required for inhibition of angiogenesis through modulating JAK2/STAT3 activity in ROP development.Biomed Pharmacother2020
31616065A phase II study of reduced intensity double umbilical cord blood transplantation using fludarabine, melphalan, and low dose total body irradiation.Bone Marrow Transplant2020
29740197IKKα deficiency disrupts the development of marginal zone and follicular B cells.Genes Immun2019
29740197IKKα deficiency disrupts the development of marginal zone and follicular B cells.Genes Immun2019
29311298IKKα inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways.Proc Natl Acad Sci U S A2018
29311298IKKα inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways.Proc Natl Acad Sci U S A2018
29758393Phase I Trial of Brentuximab Vedotin for Steroid-Refractory Chronic Graft-versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation.Biol Blood Marrow Transplant2018
29592876Third-party fecal microbiota transplantation following allo-HCT reconstitutes microbiome diversity.Blood Adv2018
29844930Macrophage inducible nitric oxide synthase circulates inflammation and promotes lung carcinogenesis.Cell Death Discov2018
29844930Macrophage inducible nitric oxide synthase circulates inflammation and promotes lung carcinogenesis.Cell Death Discov2018
29592876Third-party fecal microbiota transplantation following allo-HCT reconstitutes microbiome diversity.Blood Adv2018
29758393Phase I Trial of Brentuximab Vedotin for Steroid-Refractory Chronic Graft-versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation.Biol Blood Marrow Transplant2018
29296838Phase 1 study of the Hedgehog pathway inhibitor sonidegib for steroid-refractory chronic graft-versus-host disease.Blood Adv2017
28407484Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis.Cell Host Microbe2017
28473406Phase 1 multicenter trial of brentuximab vedotin for steroid-refractory acute graft-versus-host disease.Blood2017
29296838Phase 1 study of the Hedgehog pathway inhibitor sonidegib for steroid-refractory chronic graft-versus-host disease.Blood Adv2017
28407484Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis.Cell Host Microbe2017
28473406Phase 1 multicenter trial of brentuximab vedotin for steroid-refractory acute graft-versus-host disease.Blood2017
26862848Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma.Oncotarget2016
26862848Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma.Oncotarget2016
25376833IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells.FASEB J2015
25376833IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells.FASEB J2015
25266676IKKα negatively regulates ASC-dependent inflammasome activation.Nat Commun2014
25266676IKKα negatively regulates ASC-dependent inflammasome activation.Nat Commun2014
23597566The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas.Cancer Cell2013
23868856Mouse model resembling human lung cancer.Oncotarget2013
24290756An IKKα-nucleophosmin axis utilizes inflammatory signaling to promote genome integrity.Cell Rep2013
23597566The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas.Cancer Cell2013
24290756An IKKα-nucleophosmin axis utilizes inflammatory signaling to promote genome integrity.Cell Rep2013
23868856Mouse model resembling human lung cancer.Oncotarget2013
22544702IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis.Blood2012
22544702IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis.Blood2012
21174543Role of IKKα in skin squamous cell carcinomas.Future Oncol2011
21174543Role of IKKα in skin squamous cell carcinomas.Future Oncol2011
21566664IKKα represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the skin.Cell Death Differ2011
21566664IKKα represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the skin.Cell Death Differ2011
20304950Reduction of IKKalpha expression promotes chronic ultraviolet B exposure-induced skin inflammation and carcinogenesis.Am J Pathol2010
20304950Reduction of IKKalpha expression promotes chronic ultraviolet B exposure-induced skin inflammation and carcinogenesis.Am J Pathol2010
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Collaborators

Yinling Hu
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 18
Feng Zhu
Basic Medical College, Qingdao University
Co-authored papers 11
Daniel W McVicar
National Cancer Institute
Co-authored papers 6
Young K Song
National Cancer Institute, National Institutes of Health
Co-authored papers 6
Xiaolin Wu
Leidos Biomedical Research Inc.
Co-authored papers 6
Areej El-Jawahri
Harvard Medical School
Co-authored papers 5
Stephen K Anderson
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 5
Zhonghe Sun
Jiangsu University
Co-authored papers 4
Michael Karin
Co-authored papers 4
Sichuan Xi
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 3
David S Schrump
Center for Cancer Research, National Cancer Institute
Co-authored papers 3
Howard A Young
Center for Cancer Research, National Cancer Institute
Co-authored papers 3
Sandra Burkett
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 2
Jerome Ritz
Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital
Co-authored papers 2
Zane Gray
Tulane Cancer Center, Tulane School of Medicine
Co-authored papers 2
Ruth Nussinov
Sackler School of Medicine, Tel Aviv University
Co-authored papers 2
Salvatore Sechi
National Institute of Diabetes and Digestive and Kidney Diseases
Co-authored papers 2
Dandan Sun
Co-authored papers 1
Liyan Xue
Xuzhou Central Hospital
Co-authored papers 1
William E Seaman
Co-authored papers 1
David A Rizzieri
Duke University Medical Center
Co-authored papers 1
Peilin Zhang
Shandong Management University
Co-authored papers 1
Michael K Mansour
Co-authored papers 1
Kunio Nagashima
Co-authored papers 1
Lionel Feigenbaum
Science Applications International Corporation/Frederick
Co-authored papers 1
Raf Van de Plas
Co-authored papers 1
Giorgio Trinchieri
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Gerhard Liebisch
Co-authored papers 1
James R Bain
Duke University Medical Center
Co-authored papers 1
Katherine A Fitzgerald
Co-authored papers 1
Release 1.2