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Author Details

Kate L White
Lawrence Berkeley National Laboratory
2012
32
18
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37288664Loss of ZNF148 enhances insulin secretion in human pancreatic β cells.JCI Insight2023
37613637Quantitative Structural Mapping of Insulin Vesicle Maturation in Beta Cells.Microsc Microanal2023
37613466Soft X-ray Tomography for Mapping and Quantifying Intracellular Organelle Interactions.Microsc Microanal2023
35324950Auto-segmentation and time-dependent systematic analysis of mesoscale cellular structure in β-cells during insulin secretion.PLoS One2022
36048824An intensity-based post-processing tool for 3D instance segmentation of organelles in soft X-ray tomograms.PLoS One2022
35093200A new visual design language for biological structures in a cell.Structure2022
34942399The use of soft X-ray tomography to explore mitochondrial structure and function.Mol Metab2022
35148829Soft X-ray tomography to map and quantify organelle interactions at the mesoscale.Structure2022
34012065Live-cell imaging of glucose-induced metabolic coupling of β and α cell metabolism in health and type 2 diabetes.Commun Biol2021
33753204Assessment of scoring functions to rank the quality of 3D subtomogram clusters from cryo-electron tomography.J Struct Biol2021
34453000Bayesian metamodeling of complex biological systems across varying representations.Proc Natl Acad Sci U S A2021
33298442Visualizing insulin vesicle neighborhoods in β cells by cryo-electron tomography.Sci Adv2020
31978323Biased Signaling of the G-Protein-Coupled Receptor β<sub>2</sub>AR Is Governed by Conformational Exchange Kinetics.Structure2020
33298443Visualizing subcellular rearrangements in intact β cells using soft x-ray tomography.Sci Adv2020
30510194Crystal structure of misoprostol bound to the labor inducer prostaglandin E<sub>2</sub> receptor.Nat Chem Biol2019
31807708Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists.Sci Adv2019
31780431Federating Structural Models and Data: Outcomes from A Workshop on Archiving Integrative Structures.Structure2019
31038495The lipid phase preference of the adenosine A<sub>2A</sub> receptor depends on its ligand binding state.Chem Commun (Camb)2019
30573766Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E<sub>2</sub> receptor.Nat Chem Biol2019
29290469Allosteric Coupling of Drug Binding and Intracellular Signaling in the A<sub>2A</sub> Adenosine Receptor.Cell2018
29570991Opportunities and Challenges in Building a Spatiotemporal Multi-scale Model of the Human Pancreatic β Cell.Cell2018
29395784Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling.Structure2018
28379944Structural basis for selectivity and diversity in angiotensin II receptors.Nature2017
26963248In Vitro and In Vivo Characterization of the Alkaloid Nuciferine.PLoS One2016
25320048The G protein-biased κ-opioid receptor agonist RB-64 is analgesic with a unique spectrum of activities in vivo.J Pharmacol Exp Ther2015
26372966NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptor.Proc Natl Acad Sci U S A2015
26578769Single-molecule view of basal activity and activation mechanisms of the G protein-coupled receptor β2AR.Proc Natl Acad Sci U S A2015
25881115Receptor Reserve Moderates Mesolimbic Responses to Opioids in a Humanized Mouse Model of the OPRM1 A118G Polymorphism.Neuropsychopharmacology2015
25937170A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior.Neuron2015
24113749Identification of novel functionally selective κ-opioid receptor scaffolds.Mol Pharmacol2014
23587424Kappa-opioid receptor-selective dicarboxylic ester-derived salvinorin A ligands.Bioorg Med Chem Lett2013
23083945Psychotomimetic effects of kappa opioid receptor agonists.Biol Psychiatry2012
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Collaborators

Raymond C Stevens
iHuman Institute, ShanghaiTech University
Co-authored papers 18
Jitin Singla
Indian Institute of Technology Roorkee
Co-authored papers 10
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 8
Bryan L Roth
UNC Chapel Hill School of Medicine
Co-authored papers 8
Gye Won Han
Bridge Institute, University of Southern California
Co-authored papers 6
Angdi Li
ShanghaiTech University.
Co-authored papers 6
Valentina Loconte
University of California San Francisco
Co-authored papers 6
Kurt W??thrich
iHuman Institute, ShanghaiTech University
Co-authored papers 4
Axel Ekman
National Center for X-ray Tomography
Co-authored papers 4
Jeffrey F DiBerto
University of North Carolina at Chapel Hill
Co-authored papers 3
Carolyn A Larabell
University of California San Francisco
Co-authored papers 3
Jian-Hua Chen
University of California San Francisco
Co-authored papers 3
Gerry McDermott
University of California San Francisco
Co-authored papers 3
Frank Alber
University of California los angeles
Co-authored papers 3
Kenneth A Jacobson
National Institutes of Health
Co-authored papers 2
Helen M Berman
The State University of New Jersey
Co-authored papers 2
Wenqing Shui
iHuman Institute, ShanghaiTech University
Co-authored papers 2
Xianjun Zhang
iHuman Institute, ShanghaiTech University
Co-authored papers 2
Petr Popov
Skolkovo Institute of Science and Technology
Co-authored papers 2
Xi-Ping Huang
University of North Carolina School of Medicine
Co-authored papers 2
Kyle M McClary
Bridge Institute, University of Southern California
Co-authored papers 2
Zhan-Guo Gao
National Institutes of Health
Co-authored papers 2
Kala Bharath
University of California san francisco
Co-authored papers 1
Chuyu Zhang
ShanghaiTech University
Co-authored papers 1
Christian A Hanke
Heinrich Heine University Dusseldorf
Co-authored papers 1
Thomas D Goddard
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 1
Jihui Zhao
iHuman Institute, ShanghaiTech University
Co-authored papers 1
Shuning Zhang
iHuman Institute, ShanghaiTech University
Co-authored papers 1
Mark Le Gros
University of California San Francisco
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David Elashoff
David Geffen School of Medicine at University of California los angeles
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Release 1.2