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Author Details

Carmela Sidrauski
Calico Life Sciences LLC
1995
19
15
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34343497Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1.Immunity2021
34103529Sugar phosphate activation of the stress sensor eIF2B.Nat Commun2021
29489452The small molecule ISRIB rescues the stability and activity of Vanishing White Matter Disease eIF2B mutant complexes.Elife2018
26789650Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response.ChemMedChem2016
26928234Translational control by eIF2α phosphorylation regulates vulnerability to the synaptic and behavioral effects of cocaine.Elife2016
26928076Translational control of nicotine-evoked synaptic potentiation in mice and neuronal responses in human smokers by eIF2α.Elife2016
25719440The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly.Elife2015
25875391Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response.Elife2015
25986605Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic.Elife2015
24974795Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α.Nat Neurosci2014
23741617Pharmacological brake-release of mRNA translation enhances cognitive memory.Elife2013
11586903Purification and activity assays of the catalytic domains of the kinase/endoribonuclease Ire1p from Saccharomyces cerevisiae.Methods Enzymol2001
10619423A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response.Cell1999
10357823Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway.EMBO J1999
9695849The unfolded protein response: an intracellular signalling pathway with many surprising features.Trends Cell Biol1998
9891790Intracellular signaling from the endoplasmic reticulum to the nucleus.Annu Rev Cell Dev Biol1998
9323131The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response.Cell1997
8898194tRNA ligase is required for regulated mRNA splicing in the unfolded protein response.Cell1996
7626053Ornithine decarboxylase from Leishmania mexicana promastigotes: interaction with pyridoxal 5'-phosphate and alpha-difluoromethylornithine.Biochem Biophys Res Commun1995
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Collaborators

Peter Walter
University of California san francisco
Co-authored papers 15
Brian R Hearn
Department of Pharmaceutical Chemistry and, University of California san francisco
Co-authored papers 3
Punitha Vedantham
Department of Pharmaceutical Chemistry and, University of California san francisco
Co-authored papers 3
Adam R Renslo
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 3
Priyadarshini Jaishankar
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
Aaron S Mendez
University of California Berkeley
Co-authored papers 2
Tania Gonzalez
Co-authored papers 2
Jordan C Tsai
University of California san francisco
Co-authored papers 2
Arvin C Dar
Co-authored papers 1
Edward L Tang
Co-authored papers 1
Silke Nock
Howard Hughes Medical Institute, University of California at San Francisco
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Kevan M Shokat
University of California San Francisco
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Christopher I Amos
Baylor College of Medicine
Co-authored papers 1
Erik Verschueren
University of California San Francisco
Co-authored papers 1
Christopher S Fraser
College of Biological Sciences, University of California davis
Co-authored papers 1
Jeffery S Cox
University of California berkeley
Co-authored papers 1
Masaaki Sokabe
College of Biological Sciences, University of California davis
Co-authored papers 1
Jonathan S Weissman
Whitehead Institute for Biomedical Research
Co-authored papers 1
Martin Kampmann
Institute for Neurodegenerative Diseases, University of California san francisco
Co-authored papers 1
Billy W Newton
University of California San Francisco
Co-authored papers 1
Release 1.2